Detailed information of TA system TA042629

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 368968..369518
• Replicon: chromosome
• Accession: NZ_AP026732
• Organism: Shewanella xiamenensis strain NUITM-VS2

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: OO995_RS01770
• Protein ID: WP_037424994.1
• Coordinates: 368968..369267 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: OO995_RS01775
• Protein ID: WP_011621139.1
• Coordinates: 369276..369518 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OO995_RS01755 (NUITMVS2_03340)	364463..365029	+	567	WP_146193314.1	hypothetical protein	-
OO995_RS01760 (NUITMVS2_03350)	365342..365716	-	375	WP_011626649.1	hypothetical protein	-
OO995_RS01765 (NUITMVS2_03360)	365815..368124	-	2310	WP_037424997.1	AAA family ATPase	-
OO995_RS01770 (NUITMVS2_03370)	368968..369267	-	300	WP_037424994.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OO995_RS01775 (NUITMVS2_03380)	369276..369518	-	243	WP_011621139.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OO995_RS01780 (NUITMVS2_03390)	369713..370456	-	744	WP_037423265.1	hypothetical protein	-
OO995_RS01785 (NUITMVS2_03400)	370467..371729	-	1263	WP_037424991.1	beta-ketoacyl-ACP synthase	-
OO995_RS01790 (NUITMVS2_03410)	371730..372455	-	726	WP_037424987.1	3-ketoacyl-ACP reductase FabG2	-
OO995_RS01795 (NUITMVS2_03420)	372556..373098	-	543	WP_050991285.1	hotdog family protein	-
OO995_RS01800 (NUITMVS2_03430)	373104..374321	-	1218	WP_037424984.1	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-64)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11522.19 Da
• Isoelectric Point: 9.6429

>T42629 WP_037424994.1 NZ_AP026732:c369267-368968 [Shewanella xiamenensis]
MNNKRYKLSRLAQAHLQQIKDYTLQHFSESQWHKYKESLISGLQMLANNPGLGRSCNDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQNHLK

Nucleotide

• Length: 300 bp

>T42629 NZ_AP026732:c369267-368968 [Shewanella xiamenensis]
ATGAATAATAAACGCTATAAACTGAGTAGGTTAGCTCAGGCTCACCTACAACAGATTAAAGACTACACTCTTCAACACTT
TTCTGAGTCGCAGTGGCACAAATATAAAGAAAGCCTTATCTCCGGTTTGCAAATGTTAGCCAATAACCCCGGATTAGGCA
GAAGCTGCAACGATATTTACCCCAACGGTTTCTACTTTCCTATCGGTAAACATACCGCCTACTTCACCAAAGAAGACGAC
TTTATCCTTATCGTTGCCCTGTTAGGTCAGCCACAGCTCCCCCAAAATCATCTGAAATAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8954.18 Da
• Isoelectric Point: 5.0621

>AT42629 WP_011621139.1 NZ_AP026732:c369518-369276 [Shewanella xiamenensis]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Nucleotide

• Length: 243 bp

>AT42629 NZ_AP026732:c369518-369276 [Shewanella xiamenensis]
ATGCAAACCTTAACCGCAAATGACGCCAAACGAAATTTTGGTGAGTTGCTACTAAACGCTCAACGTGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCAGTTGTGGTCATGTCTATCCACGATTACGAACAGCTTGAGGCGATGAAAGCCGACTATC
TGAAGCACTGTTTCAACGCAGCCAAAGAAGATTTAGCAAAGGGCAATGTGGTTGATGGCGAAGATTTTCTTAACGCCCTG
TAG