Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 5331..5841 Replicon chromosome
Accession NZ_AP026671
Organism Nitratiruptor tergarcus DSM 16512

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NITER_RS00040 Protein ID WP_084274682.1
Coordinates 5331..5603 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NITER_RS00045 Protein ID WP_197685259.1
Coordinates 5584..5841 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NITER_RS00010 412..738 + 327 WP_084274689.1 UPF0175 family protein -
NITER_RS00015 735..1190 + 456 WP_084274688.1 DUF3368 domain-containing protein -
NITER_RS00020 1310..2770 - 1461 WP_084274687.1 GNAT family N-acetyltransferase -
NITER_RS00025 2760..3959 - 1200 WP_084274686.1 M20 family metallopeptidase -
NITER_RS00030 4528..4710 + 183 WP_084274684.1 hypothetical protein -
NITER_RS00035 4695..5009 + 315 WP_084274683.1 hypothetical protein -
NITER_RS00040 5331..5603 + 273 WP_084274682.1 BrnT family toxin Toxin
NITER_RS00045 5584..5841 + 258 WP_197685259.1 CopG family antitoxin Antitoxin
NITER_RS00050 6746..6946 + 201 WP_084274681.1 hypothetical protein -
NITER_RS00060 7190..8371 - 1182 WP_084274680.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
NITER_RS00065 8371..9435 - 1065 WP_084274679.1 phospho-N-acetylmuramoyl-pentapeptide- transferase -
NITER_RS00070 9513..10256 + 744 WP_084274678.1 3-oxoacyl-ACP reductase FabG -
NITER_RS00075 10313..10549 + 237 WP_084274677.1 acyl carrier protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-81)

Antitoxin

CopG antitoxin

(10-75)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10630.87 Da        Isoelectric Point: 5.2340

>T42579 WP_084274682.1 NZ_AP026671:5331-5603 [Nitratiruptor tergarcus DSM 16512]
VHIEYDPNKSKANKQKHGLDFEEARELFENDDSLIVPAKIIDGEERYALIGYLDGKCYVAIFTYRGENIRIISVRRCRKN
EERNYEEYNG

Download         Length: 273 bp

>T42579 NZ_AP026671:5331-5603 [Nitratiruptor tergarcus DSM 16512]
GTGCATATCGAATACGATCCAAACAAAAGTAAAGCCAATAAGCAAAAGCATGGCTTAGACTTTGAGGAGGCTAGAGAGCT
CTTTGAAAATGACGACTCACTCATCGTGCCAGCCAAGATTATTGATGGCGAGGAGCGATATGCGCTTATCGGCTATCTCG
ATGGCAAGTGCTATGTGGCAATATTCACCTATAGAGGTGAAAATATCAGGATCATAAGTGTGAGAAGATGTAGAAAAAAC
GAGGAGAGAAACTATGAAGAGTATAACGGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9784.38 Da        Isoelectric Point: 8.5043

>AT42579 WP_197685259.1 NZ_AP026671:5584-5841 [Nitratiruptor tergarcus DSM 16512]
MKSITAKEFDEKFDRGEDISEYLDFGKAKRVGEVKKQPTKKINIDLPQNILNLIDEEASKIGVARQALLKVWIVERLKEE
LSKPL

Download         Length: 258 bp

>AT42579 NZ_AP026671:5584-5841 [Nitratiruptor tergarcus DSM 16512]
ATGAAGAGTATAACGGCTAAAGAGTTTGATGAGAAGTTTGATAGAGGCGAAGATATAAGTGAGTATCTTGATTTTGGTAA
GGCTAAAAGAGTAGGAGAAGTTAAAAAGCAGCCTACCAAAAAGATAAATATCGACCTACCTCAAAACATCCTCAATCTCA
TCGATGAGGAAGCAAGTAAAATAGGAGTGGCAAGGCAGGCACTGCTGAAAGTGTGGATAGTGGAGAGGCTCAAAGAGGAA
CTATCCAAGCCATTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References