Detailed information of TA system TA042547

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/DUF433(antitoxin)
• Location: 2689582..2690157
• Replicon: chromosome
• Accession: NZ_AP026560
• Organism: Deinococcus aetherius strain ST0316

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: DAETH_RS13735
• Protein ID: WP_264775441.1
• Coordinates: 2689582..2689851 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: DAETH_RS13740
• Protein ID: WP_264775442.1
• Coordinates: 2689936..2690157 (-)
• Length: 74 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
-	2689936..2690157	-	222	-	-	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2688937..2700834	11897

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Domain of unknown function DUF5615 (3-56)

Antitoxin

• Protein of unknown function DUF433 (7-61)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 9860.23 Da
• Isoelectric Point: 5.5967

>T42547 WP_264775441.1 NZ_AP026560:c2689851-2689582 [Deinococcus aetherius]
VEAYSVAYLGYREAEDEVIFQAARAVSAVVVSKDADFLERLVRLGPPPQLLYVTCGNTSKARLVEIFGRHFEHAHRLLSS
GEPIVEITS

Nucleotide

• Length: 270 bp

>T42547 NZ_AP026560:c2689851-2689582 [Deinococcus aetherius]
GTGGAGGCGTACAGCGTGGCGTACCTGGGCTACCGGGAGGCGGAGGACGAAGTGATTTTTCAGGCGGCGCGGGCTGTAAG
CGCAGTGGTGGTGTCCAAGGATGCCGACTTCCTTGAGCGGCTGGTACGCCTCGGCCCCCCGCCACAACTGCTGTATGTGA
CCTGTGGAAATACGAGCAAAGCGCGACTGGTAGAGATTTTTGGTCGGCATTTTGAGCATGCCCATAGGCTGCTCTCGTCC
GGCGAGCCCATTGTTGAAATCACTTCGTAG

Antitoxin

Protein

• Length: 74 a.a.
• Molecular weight: 8197.46 Da
• Isoelectric Point: 4.4702

>AT42547 WP_264775442.1 NZ_AP026560:c2690157-2689936 [Deinococcus aetherius]
MTLLDRITVNPLQCGGRPCIRGMRIRVSDVLDLLGAGVEVDEILSDYPDLEREDIYAALIWAARYVDHPRLSA

Nucleotide

• Length: 222 bp

>AT42547 NZ_AP026560:c2690157-2689936 [Deinococcus aetherius]
ATGACCCTACTCGACCGTATCACCGTGAACCCCTTGCAGTGCGGCGGACGCCCCTGTATCCGGGGGATGCGGATTCGGGT
GAGTGACGTGCTGGACCTGCTCGGCGCAGGGGTCGAGGTGGATGAAATCTTGAGCGACTACCCGGACCTGGAGCGCGAGG
ACATTTACGCCGCGCTGATCTGGGCTGCCCGGTACGTTGACCATCCCCGACTGAGTGCTTGA