Detailed information of TA system TA042545

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-Phd
• Location: 1142240..1142916
• Replicon: chromosome
• Accession: NZ_AP026560
• Organism: Deinococcus aetherius strain ST0316

Toxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: DAETH_RS05775
• Protein ID: WP_264776967.1
• Coordinates: 1142485..1142916 (+)
• Length: 144 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: DAETH_RS05770
• Protein ID: WP_264776966.1
• Coordinates: 1142240..1142485 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-121)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (4-62)

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 15525.80 Da
• Isoelectric Point: 7.1677

>T42545 WP_264776967.1 NZ_AP026560:1142485-1142916 [Deinococcus aetherius]
MFLLDTNVVSERSRPQPDERVLSWLRTHKVGETYLSVITLAELEQGIIRLGSTKRAAELRAFLGGVEVQFAGRVLSIDRA
VARTWTSMTAGAIAAGRPPGYADSLIAATALTHGLTVVTRNIPDFEAVLGCDRLVNPWEAPNP

Nucleotide

• Length: 432 bp

>T42545 NZ_AP026560:1142485-1142916 [Deinococcus aetherius]
ATGTTCCTCCTCGACACGAACGTCGTCAGCGAACGCAGCCGTCCCCAGCCCGACGAGCGCGTTCTTTCTTGGCTCCGAAC
GCATAAGGTCGGGGAGACGTACCTCAGCGTCATCACCCTGGCCGAGTTGGAGCAGGGAATCATCCGACTTGGGAGCACCA
AGCGGGCGGCGGAACTGCGGGCGTTTCTTGGTGGCGTAGAAGTGCAGTTTGCGGGGAGGGTCCTGAGCATCGACCGGGCG
GTAGCGCGAACCTGGACGAGCATGACGGCTGGGGCCATCGCGGCGGGCAGGCCACCGGGCTACGCGGACTCGCTGATCGC
CGCGACCGCCCTCACGCACGGCCTGACCGTCGTAACACGGAACATCCCGGACTTCGAGGCGGTGCTTGGCTGTGACCGTC
TCGTGAATCCCTGGGAAGCGCCCAACCCTTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9045.30 Da
• Isoelectric Point: 4.8549

>AT42545 WP_264776966.1 NZ_AP026560:1142240-1142485 [Deinococcus aetherius]
MKEAWQLQEAKAHFSELVEAALQKGPQTVTRRGEKAVVVLAHSEFMRLTQAEKTLDEALSGAPEELVFERDRTPVPAVTL
E

Nucleotide

• Length: 246 bp

>AT42545 NZ_AP026560:1142240-1142485 [Deinococcus aetherius]
ATGAAGGAAGCTTGGCAACTTCAGGAGGCGAAAGCGCACTTCAGCGAATTGGTGGAGGCTGCCTTGCAGAAGGGACCACA
GACCGTGACGAGGCGCGGCGAGAAGGCTGTGGTGGTGCTGGCCCACAGTGAATTTATGCGACTGACTCAGGCAGAGAAGA
CGTTGGATGAGGCGCTGAGCGGAGCGCCGGAAGAACTCGTCTTTGAGCGTGACCGTACGCCCGTTCCTGCGGTCACATTG
GAGTGA