Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1871505..1871650 Replicon chromosome
Accession NZ_AP026525
Organism Klebsiella pneumoniae subsp. pneumoniae strain TUM9839

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1871541..1871643 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1871505..1871650 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO859_RS09040 (TUM9839_17540) 1866635..1868695 + 2061 WP_004151449.1 oligopeptidase B -
OO859_RS09045 (TUM9839_17550) 1868699..1869358 - 660 WP_002911407.1 exodeoxyribonuclease X -
OO859_RS09050 (TUM9839_17560) 1869437..1869667 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OO859_RS09055 (TUM9839_17570) 1869780..1870154 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OO859_RS09060 (TUM9839_17580) 1870158..1871027 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
OO859_RS09065 (TUM9839_17590) 1871044..1871382 + 339 WP_002911404.1 YebY family protein -
- 1871505..1871650 - 146 - - Antitoxin
- 1871541..1871643 + 103 - - Toxin
OO859_RS09070 1872019..1872162 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OO859_RS09075 (TUM9839_17600) 1872267..1873235 - 969 WP_014907334.1 VirK/YbjX family protein -
OO859_RS09080 (TUM9839_17610) 1873392..1874045 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
OO859_RS09085 (TUM9839_17620) 1874042..1874233 - 192 WP_002911395.1 YebW family protein -
OO859_RS09090 (TUM9839_17630) 1874331..1874570 - 240 WP_002911393.1 YebV family protein -
OO859_RS09095 (TUM9839_17640) 1874686..1876119 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T42522 NZ_AP026525:1871541-1871643 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT42522 NZ_AP026525:c1871650-1871505 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References