Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2317497..2317768 Replicon chromosome
Accession NZ_AP026116
Organism Escherichia coli strain CEC13002

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2317535..2317638 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2317497..2317768 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO850_RS11345 2314654..2316093 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OO850_RS11350 2316211..2316447 + 237 WP_001295499.1 YebV family protein -
OO850_RS11355 2316552..2316743 + 192 WP_001296140.1 YebW family protein -
OO850_RS11360 2316744..2317400 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2317497..2317768 + 272 - - Antitoxin
- 2317535..2317638 - 104 - - Toxin
OO850_RS11365 2317796..2318137 - 342 WP_000976483.1 YebY family protein -
OO850_RS11370 2318150..2319022 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
OO850_RS11375 2319026..2319400 - 375 WP_000168751.1 CopC domain-containing protein YobA -
OO850_RS11380 2319539..2319769 + 231 WP_000916763.1 DNA polymerase III subunit theta -
OO850_RS11385 2319871..2320527 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
OO850_RS11390 2320551..2321213 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T42393 NZ_AP026116:c2317638-2317535 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT42393 NZ_AP026116:2317497-2317768 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References