Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2490305..2490576 Replicon chromosome
Accession NZ_AP026108
Organism Escherichia coli strain CEC13091

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2490343..2490446 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2490305..2490576 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO842_RS12460 2487462..2488901 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OO842_RS12465 2489019..2489255 + 237 WP_001295499.1 YebV family protein -
OO842_RS12470 2489360..2489551 + 192 WP_001296140.1 YebW family protein -
OO842_RS12475 2489552..2490208 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2490305..2490576 + 272 - - Antitoxin
- 2490343..2490446 - 104 - - Toxin
OO842_RS12480 2490604..2490945 - 342 WP_000976483.1 YebY family protein -
OO842_RS12485 2490958..2491830 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
OO842_RS12490 2491834..2492208 - 375 WP_000168751.1 CopC domain-containing protein YobA -
OO842_RS12495 2492347..2492577 + 231 WP_000916763.1 DNA polymerase III subunit theta -
OO842_RS12500 2492679..2493335 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
OO842_RS12505 2493359..2494021 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T42249 NZ_AP026108:c2490446-2490343 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT42249 NZ_AP026108:2490305-2490576 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References