Detailed information of TA system TA041731

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1756619..1757532
• Replicon: chromosome
• Accession: NZ_AP025927
• Organism: Enterobacter hormaechei strain FUJ80381

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGK75_RS08385
• Protein ID: WP_032647883.1
• Coordinates: 1756619..1757092 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGK75_RS08390
• Protein ID: WP_023296216.1
• Coordinates: 1757089..1757532 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NGK75_RS08365 (FJMB80381_16390)	1752778..1754088	+	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-
NGK75_RS08370 (FJMB80381_16400)	1754085..1755020	+	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
NGK75_RS08375 (FJMB80381_16410)	1755034..1756032	+	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
NGK75_RS08380 (FJMB80381_16420)	1756042..1756596	+	555	WP_032647882.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
NGK75_RS08385 (FJMB80381_16430)	1756619..1757092	-	474	WP_032647883.1	RES domain-containing protein	Toxin
NGK75_RS08390 (FJMB80381_16440)	1757089..1757532	-	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
NGK75_RS08395 (FJMB80381_16450)	1758630..1758848	-	219	WP_002211347.1	translation initiation factor IF-1	-
NGK75_RS08400 (FJMB80381_16460)	1759133..1759837	-	705	WP_032668747.1	leucyl/phenylalanyl-tRNA--protein transferase	-
NGK75_RS08405 (FJMB80381_16470)	1759883..1761604	-	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T41731 WP_032647883.1 NZ_AP025927:c1757092-1756619 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T41731 NZ_AP025927:c1757092-1756619 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT41731 WP_023296216.1 NZ_AP025927:c1757532-1757089 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT41731 NZ_AP025927:c1757532-1757089 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA