Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 727207..727783 | Replicon | chromosome |
Accession | NZ_AP025907 | ||
Organism | Enterobacter hormaechei strain FUJ80375 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | A0A800YKM1 |
Locus tag | NGK01_RS03460 | Protein ID | WP_015572580.1 |
Coordinates | 727207..727494 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A801DSF4 |
Locus tag | NGK01_RS03465 | Protein ID | WP_017694570.1 |
Coordinates | 727481..727783 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NGK01_RS03435 (FJMB80375_06710) | 722325..723020 | + | 696 | WP_032647138.1 | winged helix-turn-helix domain-containing protein | - |
NGK01_RS03440 (FJMB80375_06720) | 723170..723640 | + | 471 | WP_032647140.1 | MarR family transcriptional regulator | - |
NGK01_RS03445 (FJMB80375_06730) | 723637..724704 | + | 1068 | WP_026094404.1 | HlyD family secretion protein | - |
NGK01_RS03450 (FJMB80375_06740) | 724694..725770 | + | 1077 | WP_015572578.1 | DUF2955 domain-containing protein | - |
NGK01_RS03455 (FJMB80375_06750) | 725767..727038 | - | 1272 | WP_032647142.1 | DUF445 domain-containing protein | - |
NGK01_RS03460 (FJMB80375_06760) | 727207..727494 | + | 288 | WP_015572580.1 | BrnT family toxin | Toxin |
NGK01_RS03465 (FJMB80375_06770) | 727481..727783 | + | 303 | WP_017694570.1 | BrnA antitoxin family protein | Antitoxin |
NGK01_RS03470 (FJMB80375_06780) | 727812..728450 | - | 639 | WP_032647144.1 | LysE family translocator | - |
NGK01_RS03475 (FJMB80375_06790) | 728489..729241 | - | 753 | WP_015572582.1 | AraC family transcriptional regulator | - |
NGK01_RS03480 (FJMB80375_06800) | 729395..730765 | + | 1371 | WP_032647147.1 | NAD-dependent succinate-semialdehyde dehydrogenase | - |
NGK01_RS03485 (FJMB80375_06810) | 730943..731488 | - | 546 | WP_006810254.1 | YfaZ family outer membrane protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11296.81 Da Isoelectric Point: 7.3587
>T41632 WP_015572580.1 NZ_AP025907:727207-727494 [Enterobacter hormaechei]
MPIEYEWDSNKAKSNLQKHAIRFEDAVLVFDDPCHLSVQDRYENGEFRWQTIGLVQGVIVILVAHTVRFESGDEIIRIIS
ARKADRKERRRYEHR
MPIEYEWDSNKAKSNLQKHAIRFEDAVLVFDDPCHLSVQDRYENGEFRWQTIGLVQGVIVILVAHTVRFESGDEIIRIIS
ARKADRKERRRYEHR
Download Length: 288 bp
>T41632 NZ_AP025907:727207-727494 [Enterobacter hormaechei]
ATGCCTATAGAGTATGAATGGGATAGCAATAAGGCGAAAAGCAATCTGCAAAAACACGCCATTCGTTTTGAAGATGCAGT
TCTGGTTTTTGACGATCCCTGCCATTTGTCTGTTCAGGATCGTTATGAAAACGGGGAGTTTCGCTGGCAAACCATTGGTC
TTGTACAGGGTGTTATTGTCATTCTGGTCGCGCACACGGTACGTTTTGAAAGCGGGGATGAAATCATACGTATCATCAGT
GCGCGTAAAGCGGATCGTAAAGAGAGGAGGCGTTATGAGCATCGTTAA
ATGCCTATAGAGTATGAATGGGATAGCAATAAGGCGAAAAGCAATCTGCAAAAACACGCCATTCGTTTTGAAGATGCAGT
TCTGGTTTTTGACGATCCCTGCCATTTGTCTGTTCAGGATCGTTATGAAAACGGGGAGTTTCGCTGGCAAACCATTGGTC
TTGTACAGGGTGTTATTGTCATTCTGGTCGCGCACACGGTACGTTTTGAAAGCGGGGATGAAATCATACGTATCATCAGT
GCGCGTAAAGCGGATCGTAAAGAGAGGAGGCGTTATGAGCATCGTTAA
Antitoxin
Download Length: 101 a.a. Molecular weight: 11482.13 Da Isoelectric Point: 10.4094
>AT41632 WP_017694570.1 NZ_AP025907:727481-727783 [Enterobacter hormaechei]
MSIVKHKRGSAPEVSARREAELKALADKPDREIDYSDIPATEDDRWAGAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
MSIVKHKRGSAPEVSARREAELKALADKPDREIDYSDIPATEDDRWAGAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
Download Length: 303 bp
>AT41632 NZ_AP025907:727481-727783 [Enterobacter hormaechei]
ATGAGCATCGTTAAACATAAACGCGGTAGTGCACCGGAAGTGAGTGCCCGCCGGGAGGCTGAACTCAAAGCGCTGGCGGA
TAAACCCGACAGGGAAATTGATTACAGCGATATACCGGCCACGGAGGATGATCGCTGGGCCGGTGCCGTGCGGGGAAAAT
TCTATCGACCGCTCAAAACTCAGGCATCAGTACGCATTGACGCCGACGTGATGGAGTGGCTTAAACGGCCAGGGAAAGGT
TACCAGACGCGGCTTAATGCCATTTTGCGCGAGGCGATGCTGCGCGATCAGAACAAAAAATAA
ATGAGCATCGTTAAACATAAACGCGGTAGTGCACCGGAAGTGAGTGCCCGCCGGGAGGCTGAACTCAAAGCGCTGGCGGA
TAAACCCGACAGGGAAATTGATTACAGCGATATACCGGCCACGGAGGATGATCGCTGGGCCGGTGCCGTGCGGGGAAAAT
TCTATCGACCGCTCAAAACTCAGGCATCAGTACGCATTGACGCCGACGTGATGGAGTGGCTTAAACGGCCAGGGAAAGGT
TACCAGACGCGGCTTAATGCCATTTTGCGCGAGGCGATGCTGCGCGATCAGAACAAAAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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