Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 294473..295069 Replicon chromosome
Accession NZ_AP025891
Organism Enterobacter hormaechei strain FUJ80182

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NGJ49_RS01405 Protein ID WP_023295756.1
Coordinates 294767..295069 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A927HL08
Locus tag NGJ49_RS01400 Protein ID WP_023295755.1
Coordinates 294473..294760 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGJ49_RS01395 (FJMB80182_02690) 292845..294476 + 1632 WP_003860350.1 Na/Pi cotransporter family protein -
NGJ49_RS01400 (FJMB80182_02700) 294473..294760 - 288 WP_023295755.1 putative addiction module antidote protein Antitoxin
NGJ49_RS01405 (FJMB80182_02710) 294767..295069 - 303 WP_023295756.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NGJ49_RS01410 (FJMB80182_02720) 295267..296139 + 873 WP_032646867.1 23S rRNA pseudouridine(2604) synthase RluF -
NGJ49_RS01415 (FJMB80182_02730) 296140..296412 - 273 WP_017382612.1 DUF3811 domain-containing protein -
NGJ49_RS01420 (FJMB80182_02740) 296463..297407 - 945 WP_032646868.1 ketopantoate/pantoate/pantothenate transporter PanS -
NGJ49_RS01425 (FJMB80182_02750) 297501..298850 - 1350 WP_251266326.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11441.24 Da        Isoelectric Point: 10.1042

>T41555 WP_023295756.1 NZ_AP025891:c295069-294767 [Enterobacter hormaechei]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDIRPVGEGISELRIHFGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

>T41555 NZ_AP025891:c295069-294767 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
CTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCTGTGGGAGAAGGTATCAGTGAACTGAGGATTC
ACTTTGGCCCGGGCTACAGGATCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.59 Da        Isoelectric Point: 5.7807

>AT41555 WP_023295755.1 NZ_AP025891:c294760-294473 [Enterobacter hormaechei]
MHKLTPYDPANALLDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp

>AT41555 NZ_AP025891:c294760-294473 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAACGCACTGCTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCAGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTGGGTTAACAATCAAACCCTCTGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References