Detailed information of TA system TA041464

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1759297..1760210
• Replicon: chromosome
• Accession: NZ_AP025871
• Organism: Enterobacter hormaechei strain FUJ80152

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGJ83_RS08405
• Protein ID: WP_032647883.1
• Coordinates: 1759297..1759770 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGJ83_RS08410
• Protein ID: WP_023296216.1
• Coordinates: 1759767..1760210 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NGJ83_RS08385 (FJMB80152_16400)	1755456..1756766	+	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-
NGJ83_RS08390 (FJMB80152_16410)	1756763..1757698	+	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
NGJ83_RS08395 (FJMB80152_16420)	1757712..1758710	+	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
NGJ83_RS08400 (FJMB80152_16430)	1758720..1759274	+	555	WP_032647882.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
NGJ83_RS08405 (FJMB80152_16440)	1759297..1759770	-	474	WP_032647883.1	RES domain-containing protein	Toxin
NGJ83_RS08410 (FJMB80152_16450)	1759767..1760210	-	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
NGJ83_RS08415 (FJMB80152_16460)	1761308..1761526	-	219	WP_002211347.1	translation initiation factor IF-1	-
NGJ83_RS08420 (FJMB80152_16470)	1761811..1762515	-	705	WP_032668747.1	leucyl/phenylalanyl-tRNA--protein transferase	-
NGJ83_RS08425 (FJMB80152_16480)	1762561..1764282	-	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T41464 WP_032647883.1 NZ_AP025871:c1759770-1759297 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T41464 NZ_AP025871:c1759770-1759297 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT41464 WP_023296216.1 NZ_AP025871:c1760210-1759767 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT41464 NZ_AP025871:c1760210-1759767 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA