Detailed information of TA system TA041446

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1757959..1758872
• Replicon: chromosome
• Accession: NZ_AP025867
• Organism: Enterobacter hormaechei strain FUJ80151

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGK26_RS08395
• Protein ID: WP_032647883.1
• Coordinates: 1757959..1758432 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: NGK26_RS08400
• Protein ID: WP_023296216.1
• Coordinates: 1758429..1758872 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NGK26_RS08375 (FJMB80151_16370)	1754118..1755428	+	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-
NGK26_RS08380 (FJMB80151_16380)	1755425..1756360	+	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
NGK26_RS08385 (FJMB80151_16390)	1756374..1757372	+	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
NGK26_RS08390 (FJMB80151_16400)	1757382..1757936	+	555	WP_032647882.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
NGK26_RS08395 (FJMB80151_16410)	1757959..1758432	-	474	WP_032647883.1	RES domain-containing protein	Toxin
NGK26_RS08400 (FJMB80151_16420)	1758429..1758872	-	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
NGK26_RS08405 (FJMB80151_16430)	1759970..1760188	-	219	WP_002211347.1	translation initiation factor IF-1	-
NGK26_RS08410 (FJMB80151_16440)	1760473..1761177	-	705	WP_032668747.1	leucyl/phenylalanyl-tRNA--protein transferase	-
NGK26_RS08415 (FJMB80151_16450)	1761223..1762944	-	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T41446 WP_032647883.1 NZ_AP025867:c1758432-1757959 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T41446 NZ_AP025867:c1758432-1757959 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT41446 WP_023296216.1 NZ_AP025867:c1758872-1758429 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT41446 NZ_AP025867:c1758872-1758429 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA