Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | KacT-ataR/DUF1778(antitoxin) |
Location | 1866526..1867323 | Replicon | chromosome |
Accession | NZ_AP025863 | ||
Organism | Enterobacter hormaechei strain FUJ80146 |
Toxin (Protein)
Gene name | KacT | Uniprot ID | A0A222RDD1 |
Locus tag | NGJ48_RS08870 | Protein ID | WP_032647926.1 |
Coordinates | 1866802..1867323 (+) | Length | 174 a.a. |
Antitoxin (Protein)
Gene name | ataR | Uniprot ID | A0A331QJY7 |
Locus tag | NGJ48_RS08865 | Protein ID | WP_015570876.1 |
Coordinates | 1866526..1866795 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NGJ48_RS08830 (FJMB80146_17310) | 1862066..1862425 | + | 360 | WP_032647921.1 | helix-turn-helix domain-containing protein | - |
NGJ48_RS08835 | 1862504..1862599 | - | 96 | Protein_1718 | transcriptional regulator | - |
NGJ48_RS08840 (FJMB80146_17330) | 1862752..1863993 | + | 1242 | WP_032647923.1 | bifunctional glucose-1-phosphatase/inositol phosphatase | - |
NGJ48_RS08845 (FJMB80146_17340) | 1864026..1864253 | - | 228 | WP_006809324.1 | YccJ family protein | - |
NGJ48_RS08850 (FJMB80146_17350) | 1864272..1864868 | - | 597 | WP_006809323.1 | NAD(P)H:quinone oxidoreductase | - |
NGJ48_RS08855 (FJMB80146_17360) | 1865260..1865430 | + | 171 | WP_001273664.1 | general stress protein | - |
NGJ48_RS08860 (FJMB80146_17370) | 1865547..1866452 | + | 906 | WP_017693666.1 | DMT family transporter | - |
NGJ48_RS08865 (FJMB80146_17380) | 1866526..1866795 | + | 270 | WP_015570876.1 | DUF1778 domain-containing protein | Antitoxin |
NGJ48_RS08870 (FJMB80146_17390) | 1866802..1867323 | + | 522 | WP_032647926.1 | GNAT family N-acetyltransferase | Toxin |
NGJ48_RS08875 (FJMB80146_17400) | 1867382..1868704 | - | 1323 | WP_032647928.1 | pyrimidine utilization transport protein G | - |
NGJ48_RS08880 (FJMB80146_17410) | 1868726..1869217 | - | 492 | WP_032647931.1 | pyrimidine utilization flavin reductase protein F | - |
NGJ48_RS08885 (FJMB80146_17420) | 1869230..1869820 | - | 591 | WP_032647932.1 | malonic semialdehyde reductase | - |
NGJ48_RS08890 (FJMB80146_17430) | 1869830..1870630 | - | 801 | WP_032647935.1 | pyrimidine utilization protein D | - |
NGJ48_RS08895 (FJMB80146_17440) | 1870638..1871024 | - | 387 | WP_015570870.1 | pyrimidine utilization protein C | - |
NGJ48_RS08900 (FJMB80146_17450) | 1871036..1871725 | - | 690 | WP_017384771.1 | pyrimidine utilization protein B | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 174 a.a. Molecular weight: 19451.21 Da Isoelectric Point: 7.4318
>T41428 WP_032647926.1 NZ_AP025863:1866802-1867323 [Enterobacter hormaechei]
VANLTIEMLSEGTDYDFGDFDCGEPSLNAFLTEHLIRQHGGRILRGYLLKERDHPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAVHKELQGNEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKLGFIPLAGENSSSLF
FPTQSIERLFEQA
VANLTIEMLSEGTDYDFGDFDCGEPSLNAFLTEHLIRQHGGRILRGYLLKERDHPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAVHKELQGNEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKLGFIPLAGENSSSLF
FPTQSIERLFEQA
Download Length: 522 bp
>T41428 NZ_AP025863:1866802-1867323 [Enterobacter hormaechei]
GTGGCAAATCTCACGATCGAAATGTTATCAGAGGGAACCGATTACGATTTCGGCGATTTCGATTGTGGTGAACCCTCGCT
AAATGCCTTCCTTACCGAGCACCTGATACGTCAGCACGGCGGGCGTATTTTACGCGGCTACCTGCTTAAAGAACGCGACC
ATCCGCGTGTCCTGGGCTATTACACACTCTCGGGAAGTTGCTTTGAAAAAGCGATGCTTCCTTCAAAGACTCAGCAGCGC
CGCATCCCATACAGCAACGTCCCCAGCGTGACGCTGGGGCGTCTGGCTGTCCATAAAGAACTCCAGGGAAACGAGTGGGG
AACAACGCTTGTCACACACGCTATGCGCGTTGTTTATCTGGCCTCGCAGGCTGTTGGCGTCCACGGAATTTTTGTGGATG
CGCTTAACGAACGGGCCAAACGATTTTATCTGAAGCTGGGGTTTATCCCGCTGGCAGGTGAAAACAGCAGTTCGCTGTTC
TTCCCCACGCAATCTATAGAACGACTGTTTGAGCAGGCGTGA
GTGGCAAATCTCACGATCGAAATGTTATCAGAGGGAACCGATTACGATTTCGGCGATTTCGATTGTGGTGAACCCTCGCT
AAATGCCTTCCTTACCGAGCACCTGATACGTCAGCACGGCGGGCGTATTTTACGCGGCTACCTGCTTAAAGAACGCGACC
ATCCGCGTGTCCTGGGCTATTACACACTCTCGGGAAGTTGCTTTGAAAAAGCGATGCTTCCTTCAAAGACTCAGCAGCGC
CGCATCCCATACAGCAACGTCCCCAGCGTGACGCTGGGGCGTCTGGCTGTCCATAAAGAACTCCAGGGAAACGAGTGGGG
AACAACGCTTGTCACACACGCTATGCGCGTTGTTTATCTGGCCTCGCAGGCTGTTGGCGTCCACGGAATTTTTGTGGATG
CGCTTAACGAACGGGCCAAACGATTTTATCTGAAGCTGGGGTTTATCCCGCTGGCAGGTGAAAACAGCAGTTCGCTGTTC
TTCCCCACGCAATCTATAGAACGACTGTTTGAGCAGGCGTGA
Antitoxin
Download Length: 90 a.a. Molecular weight: 10247.75 Da Isoelectric Point: 5.8836
>AT41428 WP_015570876.1 NZ_AP025863:1866526-1866795 [Enterobacter hormaechei]
MPALKKQRIDLRLSDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWIAVMDAIDNPPEPNERLKR
AAKRLRNME
MPALKKQRIDLRLSDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWIAVMDAIDNPPEPNERLKR
AAKRLRNME
Download Length: 270 bp
>AT41428 NZ_AP025863:1866526-1866795 [Enterobacter hormaechei]
ATGCCAGCACTCAAAAAACAGCGTATCGATCTTCGCCTGTCGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACCAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGTGCTGCCGAAGTCATCGAACAGCATCGGCGTC
TCGTATTAAACGAAGCCTCATGGATTGCCGTTATGGATGCCATCGACAATCCGCCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
ATGCCAGCACTCAAAAAACAGCGTATCGATCTTCGCCTGTCGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACCAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGTGCTGCCGAAGTCATCGAACAGCATCGGCGTC
TCGTATTAAACGAAGCCTCATGGATTGCCGTTATGGATGCCATCGACAATCCGCCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A222RDD1 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A331QJY7 |