Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 294471..295067 Replicon chromosome
Accession NZ_AP025863
Organism Enterobacter hormaechei strain FUJ80146

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NGJ48_RS01405 Protein ID WP_023295756.1
Coordinates 294765..295067 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A927HL08
Locus tag NGJ48_RS01400 Protein ID WP_023295755.1
Coordinates 294471..294758 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGJ48_RS01395 (FJMB80146_02670) 292843..294474 + 1632 WP_003860350.1 Na/Pi cotransporter family protein -
NGJ48_RS01400 (FJMB80146_02680) 294471..294758 - 288 WP_023295755.1 putative addiction module antidote protein Antitoxin
NGJ48_RS01405 (FJMB80146_02690) 294765..295067 - 303 WP_023295756.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NGJ48_RS01410 (FJMB80146_02700) 295265..296137 + 873 WP_032646867.1 23S rRNA pseudouridine(2604) synthase RluF -
NGJ48_RS01415 (FJMB80146_02710) 296138..296410 - 273 WP_017382612.1 DUF3811 domain-containing protein -
NGJ48_RS01420 (FJMB80146_02720) 296461..297405 - 945 WP_032646868.1 ketopantoate/pantoate/pantothenate transporter PanS -
NGJ48_RS01425 (FJMB80146_02730) 297499..298848 - 1350 WP_251266326.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11441.24 Da        Isoelectric Point: 10.1042

>T41423 WP_023295756.1 NZ_AP025863:c295067-294765 [Enterobacter hormaechei]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDIRPVGEGISELRIHFGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

>T41423 NZ_AP025863:c295067-294765 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
CTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCTGTGGGAGAAGGTATCAGTGAACTGAGGATTC
ACTTTGGCCCGGGCTACAGGATCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.59 Da        Isoelectric Point: 5.7807

>AT41423 WP_023295755.1 NZ_AP025863:c294758-294471 [Enterobacter hormaechei]
MHKLTPYDPANALLDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp

>AT41423 NZ_AP025863:c294758-294471 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAACGCACTGCTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCAGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTGGGTTAACAATCAAACCCTCTGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References