Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yfjZ-ypjF/CbtA-CbeA |
Location | 1082609..1083324 | Replicon | chromosome |
Accession | NZ_AP025859 | ||
Organism | Enterobacter hormaechei strain FUJ80145 |
Toxin (Protein)
Gene name | ypjF | Uniprot ID | A0A8I0UM05 |
Locus tag | NGJ45_RS05125 | Protein ID | WP_023303149.1 |
Coordinates | 1082956..1083324 (+) | Length | 123 a.a. |
Antitoxin (Protein)
Gene name | yfjZ | Uniprot ID | A0A8I0UJV2 |
Locus tag | NGJ45_RS05120 | Protein ID | WP_023303148.1 |
Coordinates | 1082609..1082935 (+) | Length | 109 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NGJ45_RS05095 (FJMB80145_09910) | 1077643..1078908 | + | 1266 | WP_023303143.1 | hypothetical protein | - |
NGJ45_RS05100 (FJMB80145_09920) | 1079217..1079651 | + | 435 | WP_023303144.1 | hypothetical protein | - |
NGJ45_RS05105 (FJMB80145_09930) | 1079710..1080549 | + | 840 | WP_023303145.1 | hypothetical protein | - |
NGJ45_RS05110 (FJMB80145_09950) | 1081239..1082060 | + | 822 | WP_023303146.1 | DUF932 domain-containing protein | - |
NGJ45_RS05115 (FJMB80145_09960) | 1082126..1082596 | + | 471 | WP_023303147.1 | DNA repair protein RadC | - |
NGJ45_RS05120 (FJMB80145_09970) | 1082609..1082935 | + | 327 | WP_023303148.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
NGJ45_RS05125 (FJMB80145_09980) | 1082956..1083324 | + | 369 | WP_023303149.1 | TA system toxin CbtA family protein | Toxin |
NGJ45_RS05130 (FJMB80145_09990) | 1083674..1084420 | - | 747 | WP_032647364.1 | class I SAM-dependent methyltransferase | - |
NGJ45_RS05135 (FJMB80145_10000) | 1084431..1084688 | - | 258 | WP_003863178.1 | YjhX family toxin | - |
NGJ45_RS05140 (FJMB80145_10010) | 1084948..1086885 | - | 1938 | WP_032647366.1 | bifunctional diguanylate cyclase/phosphodiesterase | - |
NGJ45_RS05145 (FJMB80145_10020) | 1086903..1087397 | - | 495 | WP_023295996.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1061691..1083324 | 21633 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13727.91 Da Isoelectric Point: 8.2822
>T41406 WP_023303149.1 NZ_AP025859:1082956-1083324 [Enterobacter hormaechei]
MKNLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGIILADAVNFLVDKYELVRIDRRGF
SSQGQVPYLTVTDILHARRACGLMKSCSYREVSNIVLSHSRQ
MKNLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGIILADAVNFLVDKYELVRIDRRGF
SSQGQVPYLTVTDILHARRACGLMKSCSYREVSNIVLSHSRQ
Download Length: 369 bp
>T41406 NZ_AP025859:1082956-1083324 [Enterobacter hormaechei]
ATGAAAAATCTACCTGCTACAATTTCGCGGGCGGCGAAGCCCTGCCTGTCGCCCGTTGCAGTCTGGCAAATGTTACTTAC
TCGTCTGCTTGAACAGCACTATGGTCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTAATTAAGGAACATATTG
ATGCTGGGATTATCCTGGCCGATGCAGTCAACTTCCTGGTAGATAAGTACGAACTGGTTCGCATTGATCGCAGAGGATTT
AGCTCACAGGGACAAGTACCATATTTGACCGTGACAGATATCCTTCATGCCAGAAGAGCATGTGGATTAATGAAAAGTTG
CTCTTATCGGGAAGTAAGTAATATTGTTCTTAGTCATTCGCGGCAGTGA
ATGAAAAATCTACCTGCTACAATTTCGCGGGCGGCGAAGCCCTGCCTGTCGCCCGTTGCAGTCTGGCAAATGTTACTTAC
TCGTCTGCTTGAACAGCACTATGGTCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTAATTAAGGAACATATTG
ATGCTGGGATTATCCTGGCCGATGCAGTCAACTTCCTGGTAGATAAGTACGAACTGGTTCGCATTGATCGCAGAGGATTT
AGCTCACAGGGACAAGTACCATATTTGACCGTGACAGATATCCTTCATGCCAGAAGAGCATGTGGATTAATGAAAAGTTG
CTCTTATCGGGAAGTAAGTAATATTGTTCTTAGTCATTCGCGGCAGTGA
Antitoxin
Download Length: 109 a.a. Molecular weight: 12215.04 Da Isoelectric Point: 7.0266
>AT41406 WP_023303148.1 NZ_AP025859:1082609-1082935 [Enterobacter hormaechei]
MSLIPAHEWGIKSDIVPRLGVRLVQEGNRLHYLADRASITGKFSDAECLKLDIVFPHFIRQMESMLTTGEMNSRHAHCVT
LYHNGFTCEADTLGSCGYVYIAIYPTQR
MSLIPAHEWGIKSDIVPRLGVRLVQEGNRLHYLADRASITGKFSDAECLKLDIVFPHFIRQMESMLTTGEMNSRHAHCVT
LYHNGFTCEADTLGSCGYVYIAIYPTQR
Download Length: 327 bp
>AT41406 NZ_AP025859:1082609-1082935 [Enterobacter hormaechei]
ATGTCATTAATACCAGCCCATGAATGGGGGATAAAAAGCGATATTGTTCCACGGCTTGGAGTCAGATTAGTTCAGGAAGG
CAACCGGCTGCACTATCTGGCTGACCGGGCTAGTATCACCGGTAAGTTCAGTGACGCCGAATGCCTGAAGTTGGATATCG
TATTTCCGCATTTTATCCGTCAGATGGAATCGATGCTGACCACTGGTGAAATGAATTCTCGCCATGCCCACTGTGTCACT
CTGTACCACAACGGTTTCACCTGCGAAGCCGATACCCTTGGTAGTTGCGGCTACGTATACATCGCCATTTATCCCACTCA
ACGCTAA
ATGTCATTAATACCAGCCCATGAATGGGGGATAAAAAGCGATATTGTTCCACGGCTTGGAGTCAGATTAGTTCAGGAAGG
CAACCGGCTGCACTATCTGGCTGACCGGGCTAGTATCACCGGTAAGTTCAGTGACGCCGAATGCCTGAAGTTGGATATCG
TATTTCCGCATTTTATCCGTCAGATGGAATCGATGCTGACCACTGGTGAAATGAATTCTCGCCATGCCCACTGTGTCACT
CTGTACCACAACGGTTTCACCTGCGAAGCCGATACCCTTGGTAGTTGCGGCTACGTATACATCGCCATTTATCCCACTCA
ACGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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