Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 2297555..2298294 | Replicon | chromosome |
Accession | NZ_AP025790 | ||
Organism | Enterobacter hormaechei strain FUJ80014 |
Toxin (Protein)
Gene name | tacT | Uniprot ID | A0A3S0FZ61 |
Locus tag | NGK33_RS11015 | Protein ID | WP_022648141.1 |
Coordinates | 2297555..2298040 (-) | Length | 162 a.a. |
Antitoxin (Protein)
Gene name | tacA | Uniprot ID | A0A837FCR9 |
Locus tag | NGK33_RS11020 | Protein ID | WP_003857131.1 |
Coordinates | 2298028..2298294 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NGK33_RS10990 (FJMB80014_21490) | 2293711..2294733 | + | 1023 | WP_022648135.1 | alpha/beta hydrolase | - |
NGK33_RS10995 (FJMB80014_21500) | 2294829..2295593 | + | 765 | WP_022648136.1 | SDR family oxidoreductase | - |
NGK33_RS11000 (FJMB80014_21520) | 2296260..2296523 | + | 264 | WP_022648138.1 | DUF4225 domain-containing protein | - |
NGK33_RS11005 (FJMB80014_21530) | 2296498..2296827 | - | 330 | WP_022648139.1 | hypothetical protein | - |
NGK33_RS11010 (FJMB80014_21540) | 2296960..2297529 | + | 570 | WP_022648140.1 | hypothetical protein | - |
NGK33_RS11015 (FJMB80014_21550) | 2297555..2298040 | - | 486 | WP_022648141.1 | GNAT family N-acetyltransferase | Toxin |
NGK33_RS11020 (FJMB80014_21560) | 2298028..2298294 | - | 267 | WP_003857131.1 | DUF1778 domain-containing protein | Antitoxin |
NGK33_RS11025 (FJMB80014_21570) | 2298358..2299287 | - | 930 | WP_022648142.1 | LysR family transcriptional regulator | - |
NGK33_RS11030 (FJMB80014_21580) | 2299417..2300805 | + | 1389 | WP_022648143.1 | MFS transporter | - |
NGK33_RS11035 (FJMB80014_21590) | 2300784..2301341 | - | 558 | WP_022648144.1 | OmpH family outer membrane protein | - |
NGK33_RS11040 (FJMB80014_21600) | 2301462..2302598 | - | 1137 | WP_022648145.1 | type 1 fimbrial protein | - |
NGK33_RS11045 (FJMB80014_21610) | 2302622..2303200 | - | 579 | WP_022648146.1 | fimbrial protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2274688..2298294 | 23606 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 162 a.a. Molecular weight: 17558.24 Da Isoelectric Point: 9.6275
>T41033 WP_022648141.1 NZ_AP025790:c2298040-2297555 [Enterobacter hormaechei]
VGRVTPPEPLSSVHQLAEFISGEAVLDEWLKQRGLKNQALGAARTFVVCKTGTKQVAGFYSLATGSVNHTEATGNLRRNM
PDPIPVIILARLAVDVSIRGNGLGADLLQDAVLRCYRVAENIGVRAIMVHALTEDAKAFYIHHGFKASQTQERTLFLRLP
Q
VGRVTPPEPLSSVHQLAEFISGEAVLDEWLKQRGLKNQALGAARTFVVCKTGTKQVAGFYSLATGSVNHTEATGNLRRNM
PDPIPVIILARLAVDVSIRGNGLGADLLQDAVLRCYRVAENIGVRAIMVHALTEDAKAFYIHHGFKASQTQERTLFLRLP
Q
Download Length: 486 bp
>T41033 NZ_AP025790:c2298040-2297555 [Enterobacter hormaechei]
GTGGGACGTGTAACCCCCCCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCATCAGTGGAGAGGCCGTGCTTGA
CGAATGGTTAAAACAAAGAGGTCTGAAAAACCAGGCGCTTGGCGCAGCCCGAACGTTTGTCGTTTGTAAAACGGGCACAA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGGAAGCGACAGGTAATTTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATTCTTGCCCGTCTGGCTGTCGATGTCTCAATACGCGGAAATGGGTTGGGAGCCGATTT
ACTCCAGGATGCGGTTTTACGCTGTTATCGGGTAGCAGAGAATATTGGGGTGCGGGCGATCATGGTTCATGCACTCACTG
AGGACGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCAGGCTTCCT
CAGTAG
GTGGGACGTGTAACCCCCCCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCATCAGTGGAGAGGCCGTGCTTGA
CGAATGGTTAAAACAAAGAGGTCTGAAAAACCAGGCGCTTGGCGCAGCCCGAACGTTTGTCGTTTGTAAAACGGGCACAA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGGAAGCGACAGGTAATTTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATTCTTGCCCGTCTGGCTGTCGATGTCTCAATACGCGGAAATGGGTTGGGAGCCGATTT
ACTCCAGGATGCGGTTTTACGCTGTTATCGGGTAGCAGAGAATATTGGGGTGCGGGCGATCATGGTTCATGCACTCACTG
AGGACGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCAGGCTTCCT
CAGTAG
Antitoxin
Download Length: 89 a.a. Molecular weight: 10090.50 Da Isoelectric Point: 4.3837
>AT41033 WP_003857131.1 NZ_AP025790:c2298294-2298028 [Enterobacter hormaechei]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVADDPAIEKLL
ARKPQWDV
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVADDPAIEKLL
ARKPQWDV
Download Length: 267 bp
>AT41033 NZ_AP025790:c2298294-2298028 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAACTCAATCTTAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGTACTGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAAAATGTGATCCTCGATCGGCGTGTATTCAATT
TTAACGATGAACAGTATGCAGAGTTCATTGATATGCTTGATGCCCCGGTCGCCGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA
ATGAAATCAGATGTTCAACTCAATCTTAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGTACTGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAAAATGTGATCCTCGATCGGCGTGTATTCAATT
TTAACGATGAACAGTATGCAGAGTTCATTGATATGCTTGATGCCCCGGTCGCCGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S0FZ61 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A837FCR9 |