Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 4847283..4847895 Replicon chromosome
Accession NZ_AP025732
Organism Nostoc cf. commune SO-36

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ANSO36C_RS21900 Protein ID WP_251956220.1
Coordinates 4847283..4847648 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ANSO36C_RS21905 Protein ID WP_251956221.1
Coordinates 4847638..4847895 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ANSO36C_RS21875 4842368..4842624 + 257 Protein_4353 type II toxin-antitoxin system HicA family toxin -
ANSO36C_RS21880 (ANSO36C_44500) 4842631..4842966 + 336 WP_251960405.1 type II toxin-antitoxin system HicB family antitoxin -
ANSO36C_RS21885 (ANSO36C_44510) 4843050..4843280 + 231 WP_251956217.1 hypothetical protein -
ANSO36C_RS21890 (ANSO36C_44520) 4843294..4846086 - 2793 WP_251956218.1 preprotein translocase subunit SecA -
ANSO36C_RS21895 (ANSO36C_44530) 4846528..4847097 - 570 WP_251956219.1 cytochrome C -
ANSO36C_RS21900 (ANSO36C_44540) 4847283..4847648 - 366 WP_251956220.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ANSO36C_RS21905 (ANSO36C_44550) 4847638..4847895 - 258 WP_251956221.1 hypothetical protein Antitoxin
ANSO36C_RS21910 (ANSO36C_44560) 4847920..4848234 + 315 WP_251956222.1 hypothetical protein -
ANSO36C_RS21915 (ANSO36C_44570) 4848426..4849334 - 909 WP_251960406.1 MoxR family ATPase -
ANSO36C_RS21920 (ANSO36C_44580) 4849520..4850599 - 1080 WP_251956223.1 bifunctional riboflavin kinase/FAD synthetase -
ANSO36C_RS21925 (ANSO36C_44590) 4851088..4851984 - 897 WP_251956224.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13875.76 Da        Isoelectric Point: 6.3897

>T40693 WP_251956220.1 NZ_AP025732:c4847648-4847283 [Nostoc cf. commune SO-36]
MPNEQPLVLIDLTPEYKQNLRDLSKRFRNIRSDVQAIIEQLQQGNFVGDRIAGIGEEYIIYKRRVRNSSIQKGKSAGYRL
IYQVESPTSILLLTIYSKSDREDIGVNEIRDILADFSGESV

Download         Length: 366 bp

>T40693 NZ_AP025732:c4847648-4847283 [Nostoc cf. commune SO-36]
ATGCCGAATGAACAGCCATTGGTATTAATCGATTTAACTCCTGAATATAAACAAAACTTGCGCGATCTTTCTAAGAGATT
TCGCAATATTCGCTCTGATGTTCAAGCGATTATTGAGCAATTACAGCAAGGCAATTTTGTCGGCGATCGCATTGCGGGTA
TCGGTGAAGAGTATATTATTTACAAGCGAAGAGTTCGCAACAGTAGTATCCAAAAAGGTAAGAGTGCTGGATACCGATTG
ATTTATCAAGTTGAGTCACCTACAAGTATTTTGCTATTAACGATTTATTCCAAGTCTGATCGAGAAGATATTGGTGTAAA
TGAAATCCGAGATATTTTGGCTGATTTTTCTGGTGAGTCAGTTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9389.58 Da        Isoelectric Point: 4.1056

>AT40693 WP_251956221.1 NZ_AP025732:c4847895-4847638 [Nostoc cf. commune SO-36]
MKAIEVTGRIDSQGNLVLDEPIQGSTYPHQVRVIVLVPEPAEAEEVDPDDTPIEEIKASLRRALQQAKAGQRLPLSEMWE
GIDAE

Download         Length: 258 bp

>AT40693 NZ_AP025732:c4847895-4847638 [Nostoc cf. commune SO-36]
ATGAAAGCGATCGAAGTTACCGGTAGGATTGACTCTCAAGGAAACCTAGTTTTAGATGAGCCGATTCAGGGAAGCACTTA
TCCTCATCAGGTTCGGGTAATTGTGTTGGTTCCAGAACCAGCAGAAGCAGAAGAGGTTGACCCTGATGATACACCCATTG
AGGAGATTAAAGCTAGCTTGAGAAGAGCCTTGCAGCAAGCAAAAGCTGGTCAACGCCTACCATTATCCGAAATGTGGGAG
GGAATCGATGCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References