Detailed information of TA system TA040692

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 4691363..4691899
• Replicon: chromosome
• Accession: NZ_AP025732
• Organism: Nostoc cf. commune SO-36

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ANSO36C_RS21145
• Protein ID: WP_251956103.1
• Coordinates: 4691363..4691662 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: ANSO36C_RS21150
• Protein ID: WP_251956104.1
• Coordinates: 4691666..4691899 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ANSO36C_RS21125	4686801..4688786	+	1986	WP_251956100.1	EamA family transporter	-
ANSO36C_RS21130	4688997..4690535	-	1539	Protein_4202	glycosyltransferase family 39 protein	-
ANSO36C_RS21135 (ANSO36C_42930)	4690662..4691027	-	366	WP_251956101.1	clan AA aspartic protease	-
ANSO36C_RS21140 (ANSO36C_42940)	4691024..4691296	-	273	WP_251956102.1	hypothetical protein	-
ANSO36C_RS21145 (ANSO36C_42950)	4691363..4691662	-	300	WP_251956103.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ANSO36C_RS21150 (ANSO36C_42960)	4691666..4691899	-	234	WP_251956104.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
ANSO36C_RS21155 (ANSO36C_42970)	4692399..4693469	+	1071	WP_251956105.1	reverse transcriptase domain-containing protein	-
ANSO36C_RS21160 (ANSO36C_42980)	4693498..4694373	+	876	WP_251956106.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-91)

Antitoxin

• Antitoxin ParD (1-76)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11924.40 Da
• Isoelectric Point: 6.6359

>T40692 WP_251956103.1 NZ_AP025732:c4691662-4691363 [Nostoc cf. commune SO-36]
MSAFRLTELATQDLLSIGRYTQKTWGTEQRNRYLAILDDCFHLLAREPHRGRTCDDIRSGYRKYHIGRHLIFYQETNETI
DIIRILHDRMDVESYFNED

Nucleotide

• Length: 300 bp

>T40692 NZ_AP025732:c4691662-4691363 [Nostoc cf. commune SO-36]
ATGTCAGCATTTCGCCTCACTGAATTAGCCACTCAAGACTTGCTATCAATCGGTCGCTACACCCAAAAAACATGGGGAAC
TGAGCAGAGAAACCGTTATCTTGCTATCTTGGACGATTGCTTTCATCTCTTGGCACGAGAGCCACACAGGGGACGTACTT
GTGATGATATTCGCTCAGGATATCGCAAGTACCACATCGGACGACATTTGATCTTTTATCAGGAAACCAATGAAACTATC
GATATTATTCGTATTTTGCATGATCGTATGGATGTGGAGTCTTATTTCAACGAAGACTAA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8414.37 Da
• Isoelectric Point: 4.4284

>AT40692 WP_251956104.1 NZ_AP025732:c4691899-4691666 [Nostoc cf. commune SO-36]
MQKNTSVTLGEHFEAFIANQVESGRFASASEAIRAGLRLLEEREIKLAALQRALTDGENSGFADYSLSGLLAELDRE

Nucleotide

• Length: 234 bp

>AT40692 NZ_AP025732:c4691899-4691666 [Nostoc cf. commune SO-36]
ATGCAAAAAAATACAAGTGTTACCTTGGGTGAGCATTTTGAAGCGTTTATCGCCAATCAAGTTGAAAGCGGTCGTTTTGC
CAGCGCCAGTGAAGCGATTCGAGCGGGACTGCGCCTTTTAGAAGAGCGAGAAATAAAACTTGCCGCTTTGCAACGAGCAT
TGACAGATGGGGAAAATAGCGGATTTGCTGACTATTCTCTCTCAGGATTGCTTGCAGAACTTGATCGTGAATAG