Detailed information of TA system TA040691

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 2794626..2795424
• Replicon: chromosome
• Accession: NZ_AP025732
• Organism: Nostoc cf. commune SO-36

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: ANSO36C_RS12310
• Protein ID: WP_251959762.1
• Coordinates: 2794915..2795424 (+)
• Length: 170 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: ANSO36C_RS12305
• Protein ID: WP_251959761.1
• Coordinates: 2794626..2794892 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ANSO36C_RS12285 (ANSO36C_24730)	2791106..2792738	-	1633	Protein_2450	hypothetical protein	-
ANSO36C_RS12290 (ANSO36C_24740)	2793201..2793557	+	357	WP_012407303.1	iron-sulfur cluster assembly accessory protein	-
ANSO36C_RS12295 (ANSO36C_24750)	2793646..2794068	+	423	WP_251959759.1	hypothetical protein	-
ANSO36C_RS12300 (ANSO36C_24760)	2794222..2794467	+	246	WP_251959760.1	hypothetical protein	-
ANSO36C_RS12305 (ANSO36C_24770)	2794626..2794892	+	267	WP_251959761.1	DUF1778 domain-containing protein	Antitoxin
ANSO36C_RS12310 (ANSO36C_24780)	2794915..2795424	+	510	WP_251959762.1	GNAT family N-acetyltransferase	Toxin
ANSO36C_RS12315 (ANSO36C_24790)	2795611..2796667	-	1057	Protein_2456	transposase	-
ANSO36C_RS12320 (ANSO36C_24800)	2797125..2797331	+	207	WP_251959763.1	hypothetical protein	-
ANSO36C_RS12325 (ANSO36C_24810)	2797912..2798304	+	393	WP_251955951.1	transposase	-
ANSO36C_RS12330 (ANSO36C_24820)	2798262..2798858	+	597	WP_251955950.1	IS630 family transposase	-
ANSO36C_RS12335 (ANSO36C_24830)	2799368..2800300	-	933	WP_251959764.1	TIGR01777 family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (46-148)

Antitoxin

• Vibrio phage ICP1, Orf50 (16-85)

Sequences

Toxin

Protein

• Length: 170 a.a.
• Molecular weight: 18704.84 Da
• Isoelectric Point: 8.2842

>T40691 WP_251959762.1 NZ_AP025732:2794915-2795424 [Nostoc cf. commune SO-36]
MIEQTKTINAPHPLTHEHDVLEFKSKSEALNNWLKEKALKNEGDTARTFVVTVENQVIGYYCLATGSVTHLVAVSKAKRN
APDPIPCMLIGRLAVDTKWEGQGIGSGLLKDAIIRILSVSQIAGVRCILVHAKDEEAKIFYLKRGFQPSPIEPLTLMMTL
KDIRASIID

Nucleotide

• Length: 510 bp

>T40691 NZ_AP025732:2794915-2795424 [Nostoc cf. commune SO-36]
ATGATAGAACAAACAAAAACTATTAATGCTCCTCACCCACTTACTCATGAGCATGATGTATTAGAGTTTAAATCTAAATC
AGAAGCTTTGAATAACTGGCTGAAGGAGAAAGCTTTGAAAAATGAGGGGGATACGGCTAGAACTTTTGTGGTAACTGTTG
AAAATCAAGTAATAGGCTATTACTGTTTAGCAACCGGATCTGTAACTCATTTAGTAGCTGTTAGCAAAGCTAAACGGAAC
GCACCAGACCCTATACCGTGTATGCTTATTGGTAGACTAGCAGTCGATACCAAATGGGAAGGACAGGGTATAGGGTCTGG
CTTATTAAAAGATGCTATTATTCGTATTTTATCAGTATCCCAAATAGCAGGTGTTAGATGTATTTTGGTTCACGCTAAAG
ATGAAGAAGCCAAAATATTTTATTTAAAACGTGGGTTTCAACCATCACCAATAGAACCATTAACACTGATGATGACTTTA
AAAGATATTCGAGCAAGCATTATAGATTAG

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10220.78 Da
• Isoelectric Point: 9.6820

>AT40691 WP_251959761.1 NZ_AP025732:2794626-2794892 [Nostoc cf. commune SO-36]
MLARSKMDNPGRNQVINIRVQEQQRDLIDNAASILGKNRSDFVLEVACREAEKVICDKTFFALNEEKYQNFLAILNSPLK
RTKKFVNY

Nucleotide

• Length: 267 bp

>AT40691 NZ_AP025732:2794626-2794892 [Nostoc cf. commune SO-36]
ATGCTTGCCCGTTCTAAAATGGATAACCCTGGCCGTAACCAAGTAATTAATATTAGAGTTCAAGAACAACAACGGGATTT
AATTGATAATGCCGCTTCGATTCTTGGTAAGAACCGTTCTGACTTTGTGTTAGAGGTAGCCTGCCGAGAAGCTGAAAAAG
TCATCTGTGACAAAACTTTCTTCGCGTTAAACGAGGAAAAATATCAAAATTTCCTTGCTATCTTGAACTCACCACTAAAG
CGAACGAAGAAATTCGTAAATTATTAA