Detailed information of TA system TA040688

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 2430388..2430865
• Replicon: chromosome
• Accession: NZ_AP025732
• Organism: Nostoc cf. commune SO-36

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: ANSO36C_RS10625
• Protein ID: WP_251959498.1
• Coordinates: 2430388..2430558 (+)
• Length: 57 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: ANSO36C_RS10630
• Protein ID: WP_251959499.1
• Coordinates: 2430638..2430865 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ANSO36C_RS10605 (ANSO36C_21290)	2427413..2427937	-	525	WP_251959495.1	phage tail protein	-
ANSO36C_RS10610 (ANSO36C_21300)	2427937..2428176	-	240	WP_012407849.1	hypothetical protein	-
ANSO36C_RS10615 (ANSO36C_21310)	2428360..2430135	+	1776	WP_251959496.1	DUF4157 domain-containing protein	-
ANSO36C_RS10620	2430122..2430295	-	174	WP_251959497.1	hypothetical protein	-
ANSO36C_RS10625 (ANSO36C_21320)	2430388..2430558	+	171	WP_251959498.1	BrnT family toxin	Toxin
ANSO36C_RS10630 (ANSO36C_21330)	2430638..2430865	+	228	WP_251959499.1	CopG family antitoxin	Antitoxin
ANSO36C_RS10635 (ANSO36C_21340)	2431223..2431450	+	228	WP_251959500.1	hypothetical protein	-
ANSO36C_RS10640 (ANSO36C_21350)	2431988..2432647	+	660	WP_251959501.1	hypothetical protein	-
ANSO36C_RS10645 (ANSO36C_21370)	2432743..2433216	+	474	WP_251959502.1	hypothetical protein	-
ANSO36C_RS10650 (ANSO36C_21380)	2433588..2434331	-	744	WP_251959503.1	phosphotransferase	-
ANSO36C_RS10655 (ANSO36C_21390)	2434291..2434569	-	279	WP_251959504.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2411475..2436387	24912

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-54)

Antitoxin

• CopG antitoxin (2-69)

Sequences

Toxin

Protein

• Length: 57 a.a.
• Molecular weight: 6463.24 Da
• Isoelectric Point: 4.1258

>T40688 WP_251959498.1 NZ_AP025732:2430388-2430558 [Nostoc cf. commune SO-36]
VEFEFDDVKSQSNLAKHGINFLDAQELWADPDRVEIPARIEYEPRFLVIGTIAQQC

Nucleotide

• Length: 171 bp

>T40688 NZ_AP025732:2430388-2430558 [Nostoc cf. commune SO-36]
GTGGAATTTGAGTTTGACGACGTTAAAAGCCAATCCAACTTAGCAAAGCACGGAATTAACTTTCTAGATGCACAAGAACT
ATGGGCTGATCCTGATCGAGTTGAAATCCCTGCTCGGATAGAATACGAACCAAGATTTCTGGTCATCGGTACAATCGCTC
AACAATGCTAG

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8743.02 Da
• Isoelectric Point: 5.1088

>AT40688 WP_251959499.1 NZ_AP025732:2430638-2430865 [Nostoc cf. commune SO-36]
MKTTEFDAKFDQGEDITEFLDLSQAKRPGLEQKRVNVDFPAWMIEALDYEAKRLGVTRQSIIKVWLAERLAQLSR

Nucleotide

• Length: 228 bp

>AT40688 NZ_AP025732:2430638-2430865 [Nostoc cf. commune SO-36]
ATGAAAACAACAGAATTTGATGCGAAATTTGATCAGGGGGAAGACATCACCGAATTTTTAGACCTCTCCCAAGCCAAGCG
TCCAGGACTAGAGCAAAAACGAGTCAACGTTGATTTCCCAGCCTGGATGATTGAAGCATTAGATTATGAAGCAAAGCGAT
TGGGTGTCACCCGTCAGTCAATTATTAAGGTATGGCTTGCAGAACGACTTGCACAGCTATCTCGCTGA