Detailed information of TA system TA040683

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumAB/upstrm_HI1419-dnstrm_HI1420
• Location: 5313173..5313777
• Replicon: chromosome
• Accession: NZ_AP025730
• Organism: Sphaerotilus sp. FB-5

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: NGK70_RS22845
• Protein ID: WP_251970749.1
• Coordinates: 5313173..5313469 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: PumB
• Uniprot ID: -
• Locus tag: NGK70_RS22850
• Protein ID: WP_251970750.1
• Coordinates: 5313466..5313777 (+)
• Length: 104 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
-	5313173..5313469	+	297	-	-	Toxin
-	5313466..5313777	+	312	-	-	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (1-96)

Antitoxin

• Uncharacterized protein HI1420 (3-97)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11248.89 Da
• Isoelectric Point: 10.3620

>T40683 WP_251970749.1 NZ_AP025730:5313173-5313469 [Sphaerotilus sp. FB-5]
MIEIRKTQLYQQWFDGLRDKATRLRLEARVRRLSLGNPGQHRVLTGGVTEMKLDHGPGYRVYYAQRGSELVLLLVGGDKA
SQQRDIDTAVQLAKEWQP

Nucleotide

• Length: 297 bp

>T40683 NZ_AP025730:5313173-5313469 [Sphaerotilus sp. FB-5]
ATGATCGAGATCCGCAAGACGCAGCTCTATCAGCAGTGGTTCGACGGACTGCGGGACAAAGCAACCCGTCTGCGTCTGGA
GGCTAGGGTGCGCCGGCTTTCGCTGGGCAACCCAGGGCAGCACCGGGTGCTCACGGGCGGCGTCACGGAGATGAAGCTCG
ACCACGGCCCCGGATACCGGGTGTACTACGCACAGCGCGGCAGCGAACTTGTGTTGCTGCTGGTCGGCGGCGACAAGGCC
AGCCAGCAGCGCGACATCGACACCGCCGTGCAACTGGCCAAGGAGTGGCAGCCATGA

Antitoxin

Protein

• Length: 104 a.a.
• Molecular weight: 10922.45 Da
• Isoelectric Point: 4.3719

>AT40683 WP_251970750.1 NZ_AP025730:5313466-5313777 [Sphaerotilus sp. FB-5]
MTLETTKWDVQDSLQTPEDCALYIQAALEEAGDDPAYMAAVLGDVARSRGMAQTARAAGLTREGLYKAVGPDGNPSYATM
VKILRALGLRFSVVAVPGVEMTS

Nucleotide

• Length: 312 bp

>AT40683 NZ_AP025730:5313466-5313777 [Sphaerotilus sp. FB-5]
ATGACCCTCGAAACGACGAAGTGGGATGTGCAGGACAGCCTGCAGACCCCCGAAGACTGCGCGCTGTACATCCAGGCGGC
ACTCGAAGAAGCGGGCGACGACCCCGCCTACATGGCCGCCGTGCTGGGTGACGTGGCCCGCTCCCGCGGCATGGCGCAGA
CCGCCCGTGCCGCCGGGCTCACCCGCGAGGGGCTATACAAGGCAGTCGGGCCCGATGGCAACCCGAGCTACGCCACCATG
GTCAAGATCCTGCGCGCCCTGGGGCTGCGCTTCAGCGTGGTGGCGGTGCCGGGCGTGGAAATGACGTCATGA