Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ParST/RES-TIGR02293 |
| Location | 4189952..4190949 | Replicon | chromosome |
| Accession | NZ_AP025730 | ||
| Organism | Sphaerotilus sp. FB-5 | ||
Toxin (Protein)
| Gene name | ParT | Uniprot ID | - |
| Locus tag | NGK70_RS17880 | Protein ID | WP_251973818.1 |
| Coordinates | 4189952..4190437 (-) | Length | 162 a.a. |
Antitoxin (Protein)
| Gene name | ParS | Uniprot ID | - |
| Locus tag | NGK70_RS17885 | Protein ID | WP_251969844.1 |
| Coordinates | 4190443..4190949 (-) | Length | 169 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NGK70_RS17860 (CATMQ487_35480) | 4185465..4186109 | - | 645 | WP_251969840.1 | 3-isopropylmalate dehydratase small subunit | - |
| NGK70_RS17865 (CATMQ487_35490) | 4186109..4187581 | - | 1473 | WP_251969841.1 | 3-isopropylmalate dehydratase large subunit | - |
| NGK70_RS17870 (CATMQ487_35500) | 4187693..4188598 | - | 906 | WP_251969842.1 | LysR substrate-binding domain-containing protein | - |
| NGK70_RS17875 (CATMQ487_35510) | 4188676..4189854 | - | 1179 | WP_251969843.1 | GGDEF domain-containing protein | - |
| NGK70_RS17880 (CATMQ487_35520) | 4189952..4190437 | - | 486 | WP_251973818.1 | RES family NAD+ phosphorylase | Toxin |
| NGK70_RS17885 (CATMQ487_35530) | 4190443..4190949 | - | 507 | WP_251969844.1 | DUF2384 domain-containing protein | Antitoxin |
| NGK70_RS17890 (CATMQ487_35540) | 4191044..4191334 | - | 291 | WP_251969845.1 | DUF3024 domain-containing protein | - |
| NGK70_RS17895 (CATMQ487_35550) | 4191501..4193390 | - | 1890 | WP_251969846.1 | NACHT domain-containing protein | - |
| NGK70_RS17900 (CATMQ487_35560) | 4193429..4194502 | - | 1074 | WP_251969847.1 | IS630 family transposase | - |
| NGK70_RS17905 (CATMQ487_35570) | 4194612..4195139 | - | 528 | WP_251969848.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 162 a.a. Molecular weight: 17769.45 Da Isoelectric Point: 9.5918
>T40681 WP_251973818.1 NZ_AP025730:c4190437-4189952 [Sphaerotilus sp. FB-5]
MTEPLRLWRIGTDTPHYEAHDLTGRGAERSGGRWNRPGTALVYASTSRALACLETVVHLGADTLPLNRYLVEIMLPAELW
AAAVELDAATRVGWDAMPAGKVSLDWGAAWVRAGRSLLARVPSVIVPEEMNVLINPAHPDAVQLRAVKRRRWLYDARLGR
G
MTEPLRLWRIGTDTPHYEAHDLTGRGAERSGGRWNRPGTALVYASTSRALACLETVVHLGADTLPLNRYLVEIMLPAELW
AAAVELDAATRVGWDAMPAGKVSLDWGAAWVRAGRSLLARVPSVIVPEEMNVLINPAHPDAVQLRAVKRRRWLYDARLGR
G
Download Length: 486 bp
>T40681 NZ_AP025730:c4190437-4189952 [Sphaerotilus sp. FB-5]
ATGACCGAGCCGCTGCGGCTCTGGCGCATCGGTACCGACACGCCTCACTACGAGGCCCACGACCTGACGGGGCGGGGCGC
GGAACGGTCCGGCGGGCGCTGGAACCGGCCGGGCACGGCGCTGGTGTACGCCTCGACCTCCCGGGCGCTGGCCTGCCTGG
AAACCGTGGTGCACCTGGGCGCGGACACCCTGCCGCTGAATCGCTACCTGGTCGAGATCATGCTGCCGGCCGAACTGTGG
GCCGCAGCGGTCGAGCTGGATGCAGCCACCCGGGTCGGCTGGGACGCCATGCCGGCGGGCAAGGTGTCGCTGGACTGGGG
TGCGGCCTGGGTCCGGGCGGGCCGCTCGCTGCTGGCGCGGGTGCCGTCGGTGATCGTGCCTGAGGAAATGAACGTGCTGA
TCAACCCGGCCCACCCCGACGCGGTCCAGCTGCGGGCGGTGAAGCGGCGCCGGTGGCTGTACGACGCCCGGCTGGGGCGC
GGATGA
ATGACCGAGCCGCTGCGGCTCTGGCGCATCGGTACCGACACGCCTCACTACGAGGCCCACGACCTGACGGGGCGGGGCGC
GGAACGGTCCGGCGGGCGCTGGAACCGGCCGGGCACGGCGCTGGTGTACGCCTCGACCTCCCGGGCGCTGGCCTGCCTGG
AAACCGTGGTGCACCTGGGCGCGGACACCCTGCCGCTGAATCGCTACCTGGTCGAGATCATGCTGCCGGCCGAACTGTGG
GCCGCAGCGGTCGAGCTGGATGCAGCCACCCGGGTCGGCTGGGACGCCATGCCGGCGGGCAAGGTGTCGCTGGACTGGGG
TGCGGCCTGGGTCCGGGCGGGCCGCTCGCTGCTGGCGCGGGTGCCGTCGGTGATCGTGCCTGAGGAAATGAACGTGCTGA
TCAACCCGGCCCACCCCGACGCGGTCCAGCTGCGGGCGGTGAAGCGGCGCCGGTGGCTGTACGACGCCCGGCTGGGGCGC
GGATGA
Antitoxin
Download Length: 169 a.a. Molecular weight: 18300.75 Da Isoelectric Point: 4.9652
>AT40681 WP_251969844.1 NZ_AP025730:c4190949-4190443 [Sphaerotilus sp. FB-5]
MPVLPMTPPDQPPQAAAPTVPQVMERQSSYQAFADASRIERIDMVKQGVPARLLVTLADDMHVTRERLYGWLGLARATAN
RKLKADDRLSQDESERALGMARLVGQVEALVRESGQPEGFDAAQWTAGWLQRPNPALAGRTPGDFMDTADGRDLVASLVA
QMQSGAYA
MPVLPMTPPDQPPQAAAPTVPQVMERQSSYQAFADASRIERIDMVKQGVPARLLVTLADDMHVTRERLYGWLGLARATAN
RKLKADDRLSQDESERALGMARLVGQVEALVRESGQPEGFDAAQWTAGWLQRPNPALAGRTPGDFMDTADGRDLVASLVA
QMQSGAYA
Download Length: 507 bp
>AT40681 NZ_AP025730:c4190949-4190443 [Sphaerotilus sp. FB-5]
ATGCCCGTCCTGCCGATGACACCGCCCGACCAGCCGCCGCAGGCCGCCGCGCCCACCGTGCCGCAGGTGATGGAACGCCA
GTCGAGCTACCAGGCGTTCGCGGACGCCAGCCGCATCGAGCGCATCGACATGGTCAAGCAGGGCGTGCCGGCGCGGCTGC
TGGTGACGCTGGCGGACGACATGCACGTCACGCGGGAGCGGCTGTATGGCTGGCTGGGCCTGGCGCGGGCGACGGCGAAC
CGCAAGCTCAAGGCCGACGACCGGCTGAGCCAGGACGAGAGCGAGCGGGCGTTGGGCATGGCACGGCTGGTCGGGCAGGT
GGAGGCGCTGGTGCGTGAGTCGGGCCAGCCCGAGGGCTTCGACGCGGCGCAGTGGACGGCCGGCTGGCTGCAGCGCCCCA
ACCCGGCGCTGGCGGGTCGCACGCCCGGCGACTTCATGGACACCGCCGATGGGCGCGACCTGGTGGCCAGCCTGGTCGCG
CAGATGCAGAGCGGGGCCTACGCCTGA
ATGCCCGTCCTGCCGATGACACCGCCCGACCAGCCGCCGCAGGCCGCCGCGCCCACCGTGCCGCAGGTGATGGAACGCCA
GTCGAGCTACCAGGCGTTCGCGGACGCCAGCCGCATCGAGCGCATCGACATGGTCAAGCAGGGCGTGCCGGCGCGGCTGC
TGGTGACGCTGGCGGACGACATGCACGTCACGCGGGAGCGGCTGTATGGCTGGCTGGGCCTGGCGCGGGCGACGGCGAAC
CGCAAGCTCAAGGCCGACGACCGGCTGAGCCAGGACGAGAGCGAGCGGGCGTTGGGCATGGCACGGCTGGTCGGGCAGGT
GGAGGCGCTGGTGCGTGAGTCGGGCCAGCCCGAGGGCTTCGACGCGGCGCAGTGGACGGCCGGCTGGCTGCAGCGCCCCA
ACCCGGCGCTGGCGGGTCGCACGCCCGGCGACTTCATGGACACCGCCGATGGGCGCGACCTGGTGGCCAGCCTGGTCGCG
CAGATGCAGAGCGGGGCCTACGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|