Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3339748..3341219 Replicon chromosome
Accession NZ_AP025730
Organism Sphaerotilus sp. FB-5

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag NGK70_RS14450 Protein ID WP_251969225.1
Coordinates 3340350..3341219 (+) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag NGK70_RS14445 Protein ID WP_251973789.1
Coordinates 3339748..3340353 (+) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGK70_RS14400 (CATMQ487_28510) 3335248..3335763 + 516 WP_251969216.1 lytic transglycosylase domain-containing protein -
NGK70_RS14405 (CATMQ487_28520) 3335760..3336509 + 750 WP_251969217.1 OmpA family protein -
NGK70_RS14410 (CATMQ487_28530) 3336597..3336941 + 345 WP_251969218.1 hypothetical protein -
NGK70_RS14415 (CATMQ487_28540) 3336971..3337270 + 300 WP_251969219.1 type IV conjugative transfer system protein TraL -
NGK70_RS14420 (CATMQ487_28550) 3337286..3337849 + 564 WP_251969220.1 type IV conjugative transfer system protein TraE -
NGK70_RS14425 (CATMQ487_28560) 3337839..3338213 + 375 WP_251969221.1 type-F conjugative transfer system secretin TraK -
NGK70_RS14430 (CATMQ487_28570) 3338161..3338730 + 570 WP_251969222.1 type-F conjugative transfer system secretin TraK -
NGK70_RS14435 (CATMQ487_28580) 3338928..3339245 - 318 WP_251969223.1 type II toxin-antitoxin system RelE/ParE family toxin -
NGK70_RS14440 (CATMQ487_28590) 3339232..3339534 - 303 WP_251969224.1 type II toxin-antitoxin system ParD family antitoxin -
NGK70_RS14445 (CATMQ487_28600) 3339748..3340353 + 606 WP_251973789.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
NGK70_RS14450 (CATMQ487_28610) 3340350..3341219 + 870 WP_251969225.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
NGK70_RS14455 (CATMQ487_28620) 3341420..3343009 + 1590 WP_251969226.1 MobH family relaxase -
NGK70_RS14460 (CATMQ487_28630) 3343023..3344930 + 1908 WP_251969227.1 conjugative transfer system coupling protein TraD -
NGK70_RS14465 (CATMQ487_28640) 3344939..3345544 + 606 WP_251969228.1 DUF4400 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-268)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 31493.43 Da        Isoelectric Point: 6.8800

>T40680 WP_251969225.1 NZ_AP025730:3340350-3341219 [Sphaerotilus sp. FB-5]
MTPAPKPASVATSVRARLLNVAKAQGVDFNQVLVRFALERILYRLAESQHAERFLLKGALLFTLWYDMPHRATRDADLLG
FGASDLAAVAATFRDIAAIAVDDGMVFDPTSVTAEEIRKEAGYGGVRVIIAGELARARCKTQIDVGFGDDVTPAPVDSVY
PVLLADLPAPRLRTYPAYTVIAEKLHAIALLGMTNSRLKDYFDLSVLLEREVLDTDLLARAIQATFERRGMAVPGTLPIG
LSDEFSHDPSRQSLWLAFLKKNELAPSLLPAVVERLRSGLAPALKRAAD

Download         Length: 870 bp

>T40680 NZ_AP025730:3340350-3341219 [Sphaerotilus sp. FB-5]
ATGACGCCTGCGCCGAAGCCGGCGTCTGTGGCCACCTCGGTCCGCGCTCGCCTGCTGAACGTTGCCAAGGCGCAGGGCGT
CGACTTCAATCAGGTGCTGGTGCGCTTCGCCCTGGAACGCATCCTCTACCGCCTCGCCGAATCGCAGCACGCCGAGCGTT
TTCTACTCAAGGGCGCGCTGCTGTTCACGCTCTGGTACGACATGCCGCACCGGGCCACGCGCGACGCCGACCTGCTCGGC
TTCGGCGCCAGCGATCTGGCTGCCGTGGCCGCGACCTTCCGTGACATTGCCGCCATCGCCGTGGACGACGGCATGGTGTT
CGACCCGACCTCGGTCACGGCCGAAGAGATCCGCAAAGAGGCCGGCTACGGTGGCGTGCGCGTGATCATCGCGGGAGAAC
TGGCCAGGGCACGGTGCAAGACGCAGATCGACGTTGGCTTTGGCGATGACGTGACTCCTGCGCCGGTCGATTCGGTGTAT
CCGGTTCTGCTGGCCGATCTGCCGGCGCCCCGACTTCGGACCTACCCCGCGTACACCGTCATCGCGGAAAAGCTCCACGC
CATCGCCCTGCTGGGCATGACCAACAGCCGCCTGAAGGACTACTTCGATCTGTCGGTGCTGCTTGAGCGGGAAGTGCTGG
ACACCGACCTGCTGGCCCGCGCCATCCAGGCGACCTTCGAGCGGCGCGGCATGGCGGTACCCGGGACACTGCCGATCGGG
CTGTCCGATGAGTTCTCGCACGATCCCTCACGGCAGTCCCTGTGGCTCGCGTTTCTCAAGAAGAACGAGCTGGCCCCCTC
GCTCCTGCCGGCCGTCGTCGAGCGGCTGCGATCCGGCTTGGCCCCCGCGCTCAAGCGAGCGGCGGATTGA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22313.95 Da        Isoelectric Point: 9.7910

>AT40680 WP_251973789.1 NZ_AP025730:3339748-3340353 [Sphaerotilus sp. FB-5]
MLADTHTQRVLDLASQKGLLRASDLVTIDAPRVVLTRLTAAGQLERVGRGLYRLPDAHGSEHEGLVTIATKVPQAVFCLL
TALQFHELTTQLPRQVWIAMPRGSHAPRIDFPPIKMVQFTGEGYTAGVEEVVRDGAKLRVYGVAKTVVDCFKHRNKIGLD
VALEALKDARAHRRASMDDLWHFAKICRVANVMRPYLESIG

Download         Length: 606 bp

>AT40680 NZ_AP025730:3339748-3340353 [Sphaerotilus sp. FB-5]
ATGCTCGCCGACACCCACACCCAGCGCGTGCTCGATCTGGCCAGCCAGAAAGGACTGCTGCGCGCCAGCGATCTGGTCAC
CATCGATGCGCCCCGGGTCGTCCTGACGCGCCTGACCGCCGCTGGCCAGCTGGAAAGGGTCGGCCGCGGGCTTTACCGGC
TGCCAGACGCCCACGGGTCGGAGCATGAAGGCCTGGTCACCATCGCCACCAAGGTGCCGCAGGCCGTGTTCTGCCTGCTC
ACGGCACTGCAGTTCCACGAGCTGACGACCCAACTGCCCCGTCAGGTCTGGATCGCCATGCCACGGGGCAGTCATGCCCC
CCGAATCGACTTTCCCCCCATCAAGATGGTGCAGTTCACGGGCGAAGGCTACACAGCAGGCGTCGAGGAAGTGGTCCGTG
ATGGCGCCAAGCTGCGGGTCTACGGCGTAGCCAAGACGGTGGTGGACTGCTTCAAACATCGCAACAAGATCGGCCTTGAT
GTGGCGCTGGAAGCCCTGAAGGACGCCCGGGCCCACCGCAGGGCCTCCATGGATGACCTCTGGCACTTCGCCAAGATCTG
CCGCGTCGCCAATGTGATGCGCCCCTACCTGGAGAGCATCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References