Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 2888640..2889541 Replicon chromosome
Accession NZ_AP025730
Organism Sphaerotilus sp. FB-5

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag NGK70_RS12560 Protein ID WP_251973534.1
Coordinates 2889041..2889541 (+) Length 167 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag NGK70_RS12555 Protein ID WP_251973533.1
Coordinates 2888640..2889011 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NGK70_RS12535 (CATMQ487_24750) 2884206..2885303 + 1098 WP_251973530.1 tRNA dihydrouridine(20/20a) synthase DusA -
NGK70_RS12540 (CATMQ487_24760) 2885320..2886552 + 1233 WP_251973531.1 GGDEF domain-containing protein -
NGK70_RS12545 (CATMQ487_24770) 2886710..2887642 + 933 WP_251973765.1 alpha/beta hydrolase -
NGK70_RS12550 (CATMQ487_24780) 2887677..2888555 + 879 WP_251973532.1 YbgC/FadM family acyl-CoA thioesterase -
NGK70_RS12555 (CATMQ487_24790) 2888640..2889011 + 372 WP_251973533.1 DUF2384 domain-containing protein Antitoxin
NGK70_RS12560 (CATMQ487_24800) 2889041..2889541 + 501 WP_251973534.1 RES family NAD+ phosphorylase Toxin
NGK70_RS12565 (CATMQ487_24810) 2889519..2891519 - 2001 WP_251973535.1 SDR family oxidoreductase -
NGK70_RS12570 (CATMQ487_24820) 2891812..2892339 + 528 WP_251973536.1 phasin family protein -
NGK70_RS12575 (CATMQ487_24830) 2892550..2893809 + 1260 WP_251973537.1 patatin-like phospholipase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-155)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(70-120)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18023.34 Da        Isoelectric Point: 6.2933

>T40677 WP_251973534.1 NZ_AP025730:2889041-2889541 [Sphaerotilus sp. FB-5]
MACWRVISPAYAGTPLSGMGAARQGGRFNRPGQEALYLSLDESTALAEYRQDNPWLPAGIICTFLVRGLRVADLSARFDP
GRWPALWSDFASDWRALWFGDAIEPPTWYMADDVVAAGWDGIVFPSQARPGGRNLVIYGSSGRPATQLAVYDPTGSLARL
RSGSPS

Download         Length: 501 bp

>T40677 NZ_AP025730:2889041-2889541 [Sphaerotilus sp. FB-5]
ATGGCCTGCTGGCGTGTCATTTCCCCCGCCTACGCGGGCACGCCCCTGTCCGGCATGGGTGCGGCGAGGCAGGGCGGGCG
GTTCAACCGGCCGGGCCAGGAGGCGCTGTACCTGTCACTGGACGAGTCCACCGCCCTGGCCGAATACCGCCAGGACAACC
CTTGGCTGCCAGCGGGCATCATATGTACCTTCCTTGTGCGGGGCCTGCGGGTGGCGGACCTGAGTGCCCGCTTCGACCCC
GGGCGCTGGCCTGCGCTGTGGAGCGACTTTGCTTCGGACTGGCGTGCTCTGTGGTTCGGCGACGCCATCGAGCCACCCAC
CTGGTACATGGCCGATGACGTTGTGGCCGCCGGGTGGGATGGCATCGTCTTCCCTTCCCAGGCGCGCCCGGGCGGCCGCA
ATCTGGTGATCTACGGCAGTTCGGGCAGGCCTGCGACGCAGTTGGCTGTCTACGACCCCACGGGCAGCCTTGCCCGCCTT
AGAAGTGGATCCCCTTCATGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13629.55 Da        Isoelectric Point: 8.4939

>AT40677 WP_251973533.1 NZ_AP025730:2888640-2889011 [Sphaerotilus sp. FB-5]
MSAVLKQPLVERFREPDTPYLSPTRVGDFFGFRVQELAERAHVHRNTPTARPQAPQLQKYLQDMLRVLAAATEMTGDAER
AAFLLRNEPLRAFGYKTADALVQEGRTEALIAYLQSLAGGAAG

Download         Length: 372 bp

>AT40677 NZ_AP025730:2888640-2889011 [Sphaerotilus sp. FB-5]
ATGTCTGCCGTCCTGAAACAACCCCTTGTCGAGCGGTTCCGCGAGCCCGACACACCCTACCTGTCCCCGACGAGGGTGGG
GGACTTCTTTGGTTTTCGCGTCCAGGAACTGGCTGAGCGGGCGCATGTGCACCGCAACACACCCACTGCACGCCCGCAGG
CGCCGCAACTGCAAAAGTACCTGCAGGACATGCTGCGTGTGCTCGCCGCCGCGACGGAGATGACCGGCGATGCCGAACGC
GCCGCCTTTCTGCTGCGCAATGAGCCCCTTCGCGCCTTCGGCTACAAGACCGCCGATGCGCTTGTACAGGAGGGGCGCAC
CGAGGCGCTCATCGCCTACCTGCAGTCGTTGGCCGGCGGTGCCGCGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References