Detailed information of TA system TA040674

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/upstrm_HI1419-dnstrm_HI1420
• Location: 1677186..1677794
• Replicon: chromosome
• Accession: NZ_AP025730
• Organism: Sphaerotilus sp. FB-5

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: NGK70_RS07440
• Protein ID: WP_251972622.1
• Coordinates: 1677498..1677794 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: NGK70_RS07435
• Protein ID: WP_251972621.1
• Coordinates: 1677186..1677494 (-)
• Length: 103 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1670018..1694254	24236
	-	flank	IS/Tn	-	-	1676054..1676659	605

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (1-96)

Antitoxin

• Uncharacterized protein HI1420 (13-99)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11029.73 Da
• Isoelectric Point: 10.0414

>T40674 WP_251972622.1 NZ_AP025730:c1677794-1677498 [Sphaerotilus sp. FB-5]
MYTVRQTPEFMQWLTGLKDGMTRRRLARRLEKVQRGNLGDVKAVGEGVCEMRESFGPGWRMYYVQRGAVLVLMLGGGDKS
TQQADIAAAQALARHIED

Nucleotide

• Length: 297 bp

>T40674 NZ_AP025730:c1677794-1677498 [Sphaerotilus sp. FB-5]
ATGTACACGGTCCGGCAAACCCCCGAGTTCATGCAGTGGCTGACCGGCCTGAAGGACGGCATGACCCGGCGCCGCCTGGC
GCGCCGACTGGAAAAGGTGCAACGCGGCAACCTGGGCGACGTGAAGGCTGTCGGCGAGGGGGTGTGCGAGATGCGCGAGT
CCTTTGGCCCCGGGTGGCGCATGTACTACGTTCAGCGCGGCGCCGTGTTGGTCTTGATGCTGGGCGGGGGCGACAAGAGC
ACCCAGCAAGCCGACATTGCAGCGGCGCAGGCCCTGGCGCGGCACATTGAGGATTGA

Antitoxin

Protein

• Length: 103 a.a.
• Molecular weight: 10882.44 Da
• Isoelectric Point: 4.6290

>AT40674 WP_251972621.1 NZ_AP025730:c1677494-1677186 [Sphaerotilus sp. FB-5]
MSDTKTIKASDLPEFDMAEHLDSDQAIAEYLTIVLEEDDPAALADALGTIARARGMTAVAADAGLTREALYKALRPTAHP
RFDTIQRVCKALGVKLVAQVAA

Nucleotide

• Length: 309 bp

>AT40674 NZ_AP025730:c1677494-1677186 [Sphaerotilus sp. FB-5]
ATGAGCGACACCAAGACGATCAAGGCTTCTGACCTGCCAGAGTTCGACATGGCGGAGCACCTGGACAGCGATCAGGCGAT
CGCCGAATACCTCACCATCGTGCTTGAAGAGGACGACCCGGCGGCCCTGGCCGATGCGCTCGGAACGATTGCCCGCGCCC
GTGGCATGACGGCTGTCGCGGCCGATGCGGGCCTGACCCGCGAAGCCCTTTACAAGGCGCTGCGGCCGACGGCACATCCG
CGCTTCGACACGATTCAACGGGTGTGCAAGGCGCTGGGGGTCAAGCTGGTGGCGCAGGTGGCCGCCTAG