Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 2614443..2615494 Replicon chromosome
Accession NZ_AP025688
Organism Tsukamurella sp. PLM1

Toxin (Protein)


Gene name pezT Uniprot ID -
Locus tag MTP03_RS13480 Protein ID WP_248488728.1
Coordinates 2614823..2615494 (+) Length 224 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID -
Locus tag MTP03_RS13475 Protein ID WP_248488727.1
Coordinates 2614443..2614826 (+) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTP03_RS13450 (MTP03_28900) 2610444..2611571 + 1128 WP_248488722.1 hypothetical protein -
MTP03_RS13455 (MTP03_28910) 2611571..2611789 + 219 WP_248488723.1 hypothetical protein -
MTP03_RS13460 (MTP03_28920) 2611786..2613039 + 1254 WP_248488724.1 TIGR02679 family protein -
MTP03_RS13465 (MTP03_28930) 2613146..2613487 + 342 WP_248488725.1 hypothetical protein -
MTP03_RS13470 (MTP03_28940) 2613721..2614344 + 624 WP_248488726.1 DUF4352 domain-containing protein -
MTP03_RS13475 (MTP03_28950) 2614443..2614826 + 384 WP_248488727.1 ParD-like family protein Antitoxin
MTP03_RS13480 (MTP03_28960) 2614823..2615494 + 672 WP_248488728.1 AAA family ATPase Toxin
MTP03_RS13485 (MTP03_28970) 2615955..2616458 + 504 WP_248488729.1 hypothetical protein -
MTP03_RS13490 (MTP03_28980) 2616495..2617955 + 1461 WP_248488730.1 oligopeptide:H+ symporter -
MTP03_RS13495 (MTP03_28990) 2618070..2619647 + 1578 WP_248488731.1 GMC family oxidoreductase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(4-97)


Sequences

Toxin        


Download         Length: 224 a.a.        Molecular weight: 25063.49 Da        Isoelectric Point: 10.0325

>T40650 WP_248488728.1 NZ_AP025688:2614823-2615494 [Tsukamurella sp. PLM1]
MSRLELVVGPNGAGKSTFVELVLAPSSGRLPFVNADVIAKARWPEAAEEHSYDAARIASATRERLLEQGDSFIAETVFSH
PSKVDLIRSALRHGFEVHLHVVMVPVELSVHRVAHRAAAGGHDVPEEKIRDRHSRLWSLVAEATLLSTTTTFYDNSRIDG
PLIVAEFAQEQPLGLARWPSWTSTELIALWGSRGGARLIRRYIRRRREEDPWRTRCRTRSRCG

Download         Length: 672 bp

>T40650 NZ_AP025688:2614823-2615494 [Tsukamurella sp. PLM1]
ATGAGCCGGCTCGAACTGGTTGTGGGCCCGAACGGCGCGGGCAAGTCGACCTTCGTCGAACTCGTCCTCGCGCCGAGCTC
GGGGCGCCTTCCCTTCGTCAACGCGGACGTCATCGCCAAGGCTCGTTGGCCGGAGGCGGCCGAGGAGCACTCCTACGACG
CCGCGCGGATCGCGAGCGCCACTCGCGAGCGACTCTTGGAGCAGGGCGACTCCTTCATCGCCGAGACCGTCTTCTCACAC
CCGTCCAAGGTCGATCTGATCCGCTCCGCGCTCAGGCACGGATTCGAGGTGCACCTGCACGTCGTGATGGTCCCTGTGGA
GCTGTCGGTCCACCGCGTCGCGCATCGGGCCGCCGCGGGCGGCCACGACGTCCCCGAGGAGAAGATTCGCGACCGGCACA
GCCGACTGTGGTCCTTGGTCGCCGAGGCCACCCTCCTGTCGACGACTACGACGTTCTACGACAACTCGAGGATCGATGGC
CCTCTGATCGTCGCCGAGTTCGCGCAGGAGCAGCCACTCGGCCTCGCCCGGTGGCCGTCGTGGACGTCCACTGAGCTCAT
CGCGTTATGGGGGTCGCGCGGCGGCGCGCGGCTGATCCGGCGGTACATTCGAAGGAGGCGGGAGGAGGATCCATGGCGGA
CTCGGTGCAGAACGAGATCGCGGTGCGGGTGA

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 13852.28 Da        Isoelectric Point: 4.5628

>AT40650 WP_248488727.1 NZ_AP025688:2614443-2614826 [Tsukamurella sp. PLM1]
MPHPTRIADDVYESAQAVSAQEGRSTAEQINHWARLGREFSIHETAARSRVEAALAGTLAVDELDAAESRVYDAEVRAGI
RERLQNVDFGSALAQRGIVTVALDDAGRMVEYYPDGSERIIAEAPAR

Download         Length: 384 bp

>AT40650 NZ_AP025688:2614443-2614826 [Tsukamurella sp. PLM1]
ATGCCGCATCCCACCCGCATCGCCGACGACGTGTACGAGAGCGCGCAGGCGGTGAGCGCACAGGAGGGTCGATCGACCGC
CGAGCAGATCAATCACTGGGCGCGGCTGGGCCGCGAATTCTCGATCCACGAGACCGCGGCCCGCAGCCGGGTGGAAGCAG
CCCTTGCAGGGACGCTCGCCGTGGATGAGCTCGACGCGGCGGAATCCCGGGTGTACGACGCGGAGGTCCGGGCCGGGATT
CGCGAGCGACTGCAGAACGTGGACTTCGGATCCGCCCTCGCGCAGCGGGGAATCGTCACCGTCGCACTCGATGACGCAGG
ACGGATGGTCGAGTACTACCCCGACGGTTCCGAGCGGATCATCGCCGAGGCTCCTGCGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References