40441

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 337952..339663 Replicon chromosome
Accession NZ_AP025589
Organism Pseudoalteromonas sp. KAN5

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag KAN5_RS01465 Protein ID WP_244390270.1
Coordinates 339016..339663 (-) Length 216 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag KAN5_RS01460 Protein ID WP_244390269.1
Coordinates 337952..339016 (-) Length 355 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KAN5_RS01450 (KAN5_02910) 334004..334750 - 747 WP_244390267.1 SprT family zinc-dependent metalloprotease -
KAN5_RS01455 (KAN5_02920) 334750..337914 - 3165 WP_244390268.1 HsdR family type I site-specific deoxyribonuclease -
KAN5_RS01460 (KAN5_02930) 337952..339016 - 1065 WP_244390269.1 macro domain-containing protein Antitoxin
KAN5_RS01465 (KAN5_02940) 339016..339663 - 648 WP_244390270.1 DUF4433 domain-containing protein Toxin
KAN5_RS01470 (KAN5_02950) 339665..340240 - 576 WP_244390271.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
KAN5_RS01475 (KAN5_02960) 340312..342093 - 1782 WP_244390272.1 DUF262 domain-containing protein -
KAN5_RS01480 (KAN5_02970) 342096..343451 - 1356 WP_244390273.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-215)

Antitoxin

Macro domain

(18-128)


Sequences

Toxin        


Download         Length: 216 a.a.        Molecular weight: 24980.56 Da        Isoelectric Point: 7.8439

>T40441 WP_244390270.1 NZ_AP025589:c339663-339016 [Pseudoalteromonas sp. KAN5]
MYNYSQTLNPQKALIWRIVHRNNIPWILDNGLYCGNSQVQSPNWEAIGSSELIQKRATHPVPIAPFGSLNDYVPFYFTPF
SPMLLNIKSGRGVIQRANEDIVILVSSLHKVEQLNLEFVYTDMHAYYQWANFYSDLSHLGKVDWPILQARNFARDLNDPA
KFERYQAEALIKQHCPINALLGIACYNAQVEQQLKQHIQQRNMNLDVIVRPGWYF

Download         Length: 648 bp

>T40441 NZ_AP025589:c339663-339016 [Pseudoalteromonas sp. KAN5]
TTGTATAACTATAGTCAAACTCTTAACCCACAAAAAGCGCTAATTTGGCGCATAGTGCATCGCAACAATATACCGTGGAT
CTTAGATAACGGTTTGTATTGTGGTAATAGTCAGGTGCAGTCACCTAATTGGGAAGCAATTGGTAGTTCGGAGTTAATAC
AAAAACGAGCAACTCACCCTGTCCCGATTGCTCCTTTTGGTTCATTAAATGACTATGTGCCTTTTTACTTTACTCCTTTC
TCACCTATGTTGCTAAACATAAAGTCAGGGCGAGGCGTTATTCAGAGGGCTAACGAAGATATCGTTATTTTGGTATCATC
ATTACATAAAGTTGAACAATTAAACTTGGAATTTGTCTATACAGACATGCATGCTTACTATCAATGGGCTAATTTCTATT
CTGACTTAAGCCACTTAGGTAAGGTAGATTGGCCTATTTTACAAGCAAGGAATTTTGCTAGAGATTTGAATGACCCAGCG
AAGTTCGAGCGATATCAAGCTGAGGCATTAATCAAACAGCATTGTCCAATAAATGCTTTATTAGGCATAGCTTGTTACAA
CGCCCAAGTTGAACAACAATTAAAACAGCATATTCAACAACGCAATATGAATTTGGACGTTATTGTACGTCCGGGATGGT
ATTTCTAA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39857.89 Da        Isoelectric Point: 7.1923

>AT40441 WP_244390269.1 NZ_AP025589:c339016-337952 [Pseudoalteromonas sp. KAN5]
MITYTQGNLLEANADALVNTVNTVGVMGKGIALMFKERFPKNMAEYASACKAKQVTTGKMFVTETGELMGPRWIVNFPTK
QHWRAKSKMEWVQDGLIDLRHFIENNNVSSIAIPPLGAGQGGLSWPEVKLEIEKALSDIENTNIIVFEPTSKYQNVAKKA
GVKKLTPARALVAELVRRYWILGMECSLLEIQKLAWFLQRTIENSGLKNELKLNFEANYYGPYANNLEHLLNALDGSYLK
SDKRIPDCDPLDVIWFNEKERQKVSTYLSTEAKEYLPALEKASEVINGFESPFGLELLSTVDWLVTRQGCDKNVESIKQG
IANWPAGAKWAQRKLTLFGDKEIEFALSSLEKLS

Download         Length: 1065 bp

>AT40441 NZ_AP025589:c339016-337952 [Pseudoalteromonas sp. KAN5]
ATGATCACTTATACACAAGGTAATTTACTCGAAGCTAACGCTGATGCACTAGTTAATACAGTGAATACTGTAGGGGTCAT
GGGGAAAGGCATTGCGTTAATGTTTAAAGAACGTTTTCCTAAAAATATGGCAGAATATGCAAGTGCATGTAAAGCTAAGC
AGGTAACTACGGGCAAAATGTTTGTTACTGAAACAGGCGAACTAATGGGGCCTAGGTGGATTGTAAATTTCCCTACCAAG
CAGCATTGGCGTGCAAAATCTAAAATGGAATGGGTTCAAGATGGTTTAATCGATCTTCGCCATTTTATAGAAAATAATAA
TGTCAGCTCTATAGCAATTCCTCCTCTTGGCGCAGGGCAAGGTGGTCTATCTTGGCCTGAGGTGAAATTGGAAATAGAAA
AAGCATTATCTGATATTGAAAACACAAATATTATTGTATTTGAACCTACCAGCAAATATCAAAATGTAGCCAAAAAAGCA
GGTGTAAAGAAACTAACCCCTGCAAGAGCGTTAGTTGCAGAATTGGTAAGACGTTATTGGATATTAGGCATGGAGTGTAG
CCTGCTAGAAATTCAAAAGTTAGCTTGGTTTTTACAGAGAACCATTGAGAATTCTGGCTTGAAAAATGAATTAAAGCTCA
ACTTCGAAGCAAATTATTATGGACCCTATGCCAACAACCTAGAGCACTTGTTAAATGCTTTAGATGGTAGTTATTTGAAA
TCAGATAAACGTATTCCTGATTGTGATCCTTTAGATGTCATCTGGTTCAATGAAAAAGAGAGGCAAAAAGTTTCGACCTA
CTTAAGTACCGAGGCGAAAGAGTATTTACCTGCATTAGAAAAAGCAAGTGAAGTAATTAATGGCTTTGAATCTCCTTTTG
GTCTTGAGCTTCTATCGACAGTAGATTGGCTTGTTACTAGACAAGGATGTGATAAGAATGTTGAGTCTATTAAGCAAGGC
ATCGCAAATTGGCCTGCTGGGGCAAAGTGGGCACAACGAAAATTAACTCTATTTGGTGATAAAGAAATTGAATTTGCTTT
ATCTAGCTTGGAAAAACTAAGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References