Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-DinJ |
| Location | 2562547..2563087 | Replicon | chromosome |
| Accession | NZ_AP025585 | ||
| Organism | Pyramidobacter piscolens strain CE91-St28 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | D1Y1I5 |
| Locus tag | MWL86_RS12260 | Protein ID | WP_009163717.1 |
| Coordinates | 2562794..2563087 (+) | Length | 98 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | D1Y1I6 |
| Locus tag | MWL86_RS12255 | Protein ID | WP_009163718.1 |
| Coordinates | 2562547..2562807 (+) | Length | 87 a.a. |
Genomic Context
Location: 2557874..2558683 (810 bp)
Type: Others
Protein ID: WP_009164667.1
Type: Others
Protein ID: WP_009164667.1
Location: 2558673..2559437 (765 bp)
Type: Others
Protein ID: WP_244388782.1
Type: Others
Protein ID: WP_244388782.1
Location: 2559438..2560313 (876 bp)
Type: Others
Protein ID: WP_009164665.1
Type: Others
Protein ID: WP_009164665.1
Location: 2560314..2560661 (348 bp)
Type: Others
Protein ID: WP_009164664.1
Type: Others
Protein ID: WP_009164664.1
Location: 2561684..2561908 (225 bp)
Type: Others
Protein ID: WP_009163720.1
Type: Others
Protein ID: WP_009163720.1
Location: 2561971..2562234 (264 bp)
Type: Others
Protein ID: WP_009163719.1
Type: Others
Protein ID: WP_009163719.1
Location: 2562547..2562807 (261 bp)
Type: Antitoxin
Protein ID: WP_009163718.1
Type: Antitoxin
Protein ID: WP_009163718.1
Location: 2562794..2563087 (294 bp)
Type: Toxin
Protein ID: WP_009163717.1
Type: Toxin
Protein ID: WP_009163717.1
Location: 2563909..2564373 (465 bp)
Type: Others
Protein ID: WP_050768840.1
Type: Others
Protein ID: WP_050768840.1
Location: 2564500..2565393 (894 bp)
Type: Others
Protein ID: WP_009163716.1
Type: Others
Protein ID: WP_009163716.1
Location: 2565570..2566595 (1026 bp)
Type: Others
Protein ID: WP_009163715.1
Type: Others
Protein ID: WP_009163715.1
Location: 2567055..2567231 (177 bp)
Type: Others
Protein ID: WP_009163714.1
Type: Others
Protein ID: WP_009163714.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MWL86_RS12225 (CE91St28_24010) | 2557874..2558683 | + | 810 | WP_009164667.1 | type I-E CRISPR-associated protein Cas5/CasD | - |
| MWL86_RS12230 (CE91St28_24020) | 2558673..2559437 | + | 765 | WP_244388782.1 | type I-E CRISPR-associated protein Cas6/Cse3/CasE | - |
| MWL86_RS12235 (CE91St28_24030) | 2559438..2560313 | + | 876 | WP_009164665.1 | type I-E CRISPR-associated endonuclease Cas1e | - |
| MWL86_RS12240 (CE91St28_24040) | 2560314..2560661 | + | 348 | WP_009164664.1 | type I-E CRISPR-associated endoribonuclease Cas2e | - |
| MWL86_RS12245 (CE91St28_24050) | 2561684..2561908 | + | 225 | WP_009163720.1 | hypothetical protein | - |
| MWL86_RS12250 | 2561971..2562234 | + | 264 | WP_009163719.1 | hypothetical protein | - |
| MWL86_RS12255 (CE91St28_24070) | 2562547..2562807 | + | 261 | WP_009163718.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| MWL86_RS12260 (CE91St28_24080) | 2562794..2563087 | + | 294 | WP_009163717.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| MWL86_RS12265 (CE91St28_24110) | 2563909..2564373 | + | 465 | WP_050768840.1 | hypothetical protein | - |
| MWL86_RS12270 (CE91St28_24120) | 2564500..2565393 | + | 894 | WP_009163716.1 | helix-turn-helix domain-containing protein | - |
| MWL86_RS12275 (CE91St28_24130) | 2565570..2566595 | + | 1026 | WP_009163715.1 | dihydrodipicolinate reductase | - |
| MWL86_RS12280 (CE91St28_24140) | 2567055..2567231 | - | 177 | WP_009163714.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11526.27 Da Isoelectric Point: 8.4955
>T40440 WP_009163717.1 NZ_AP025585:2562794-2563087 [Pyramidobacter piscolens]
MRTIKHSSAFKRDVKREKKGRYCEVFDTELLAIINNLANDVPLDEKYQDHELQRNLSGYRECHVRVDFLLLYQKIDGELK
ILRLERLGSHRQVLGIE
MRTIKHSSAFKRDVKREKKGRYCEVFDTELLAIINNLANDVPLDEKYQDHELQRNLSGYRECHVRVDFLLLYQKIDGELK
ILRLERLGSHRQVLGIE
Download Length: 294 bp
>T40440 NZ_AP025585:2562794-2563087 [Pyramidobacter piscolens]
ATGCGGACGATTAAGCACTCTTCCGCTTTCAAACGCGACGTTAAACGCGAAAAGAAAGGACGCTACTGCGAAGTCTTCGA
TACCGAGCTGCTGGCGATCATCAACAATCTTGCGAACGATGTCCCCTTGGACGAGAAATATCAAGACCACGAACTGCAAC
GCAATCTCAGCGGATATCGCGAATGCCACGTGCGCGTCGACTTTCTGCTGCTGTACCAGAAGATCGACGGTGAATTGAAA
ATCCTCCGCCTCGAACGCCTCGGTTCTCACCGCCAGGTCCTCGGAATCGAATAA
ATGCGGACGATTAAGCACTCTTCCGCTTTCAAACGCGACGTTAAACGCGAAAAGAAAGGACGCTACTGCGAAGTCTTCGA
TACCGAGCTGCTGGCGATCATCAACAATCTTGCGAACGATGTCCCCTTGGACGAGAAATATCAAGACCACGAACTGCAAC
GCAATCTCAGCGGATATCGCGAATGCCACGTGCGCGTCGACTTTCTGCTGCTGTACCAGAAGATCGACGGTGAATTGAAA
ATCCTCCGCCTCGAACGCCTCGGTTCTCACCGCCAGGTCCTCGGAATCGAATAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9647.89 Da Isoelectric Point: 5.0495
>AT40440 WP_009163718.1 NZ_AP025585:2562547-2562807 [Pyramidobacter piscolens]
MSTATINTRIDSNLKHQAEAIFSEIGLSTSQAIRLFYKQTVQSGGLPFQPDYNLPRETLEAMREAEEGKLTKITMDGLRA
MFHADD
MSTATINTRIDSNLKHQAEAIFSEIGLSTSQAIRLFYKQTVQSGGLPFQPDYNLPRETLEAMREAEEGKLTKITMDGLRA
MFHADD
Download Length: 261 bp
>AT40440 NZ_AP025585:2562547-2562807 [Pyramidobacter piscolens]
ATGTCGACCGCGACCATCAACACACGCATCGATTCGAATTTGAAACATCAAGCTGAAGCAATCTTCTCCGAGATCGGCCT
TTCCACCAGCCAGGCCATCCGACTCTTTTACAAACAGACCGTTCAATCTGGCGGCCTGCCCTTTCAGCCCGACTACAACT
TGCCCAGAGAGACCCTCGAAGCCATGAGAGAAGCCGAAGAAGGCAAACTGACGAAGATCACAATGGACGGACTGAGGGCA
ATGTTCCATGCGGACGATTAA
ATGTCGACCGCGACCATCAACACACGCATCGATTCGAATTTGAAACATCAAGCTGAAGCAATCTTCTCCGAGATCGGCCT
TTCCACCAGCCAGGCCATCCGACTCTTTTACAAACAGACCGTTCAATCTGGCGGCCTGCCCTTTCAGCCCGACTACAACT
TGCCCAGAGAGACCCTCGAAGCCATGAGAGAAGCCGAAGAAGGCAAACTGACGAAGATCACAATGGACGGACTGAGGGCA
ATGTTCCATGCGGACGATTAA