Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 1517980..1518494 Replicon chromosome
Accession NZ_AP025585
Organism Pyramidobacter piscolens strain CE91-St28

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MWL86_RS07325 Protein ID WP_244388268.1
Coordinates 1517980..1518240 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag MWL86_RS07330 Protein ID WP_244388269.1
Coordinates 1518246..1518494 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MWL86_RS07280 (CE91St28_14330) 1513737..1514048 - 312 WP_244388260.1 hypothetical protein -
MWL86_RS07285 (CE91St28_14340) 1514055..1514318 - 264 WP_244388261.1 hypothetical protein -
MWL86_RS07290 (CE91St28_14350) 1514426..1514773 - 348 WP_244388262.1 hypothetical protein -
MWL86_RS07295 (CE91St28_14360) 1514785..1515015 - 231 WP_244388263.1 hypothetical protein -
MWL86_RS07300 (CE91St28_14370) 1515077..1515364 - 288 WP_244388264.1 hypothetical protein -
MWL86_RS07305 (CE91St28_14380) 1515542..1515748 + 207 WP_244388265.1 hypothetical protein -
MWL86_RS07310 (CE91St28_14390) 1515745..1516221 + 477 WP_244388266.1 ASCH domain-containing protein -
MWL86_RS07315 (CE91St28_14410) 1516509..1517237 + 729 WP_244388267.1 phosphoadenosine phosphosulfate reductase family protein -
MWL86_RS07320 (CE91St28_14420) 1517275..1517940 + 666 WP_244389519.1 ParB/RepB/Spo0J family partition protein -
MWL86_RS07325 (CE91St28_14430) 1517980..1518240 - 261 WP_244388268.1 Txe/YoeB family addiction module toxin Toxin
MWL86_RS07330 (CE91St28_14440) 1518246..1518494 - 249 WP_244388269.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MWL86_RS07335 (CE91St28_14450) 1518582..1519160 + 579 WP_244388270.1 helix-turn-helix domain-containing protein -
MWL86_RS07340 (CE91St28_14460) 1519087..1520340 + 1254 WP_244389520.1 PBSX family phage terminase large subunit -
MWL86_RS07345 (CE91St28_14470) 1520365..1521756 + 1392 WP_244388271.1 DUF4055 domain-containing protein -
MWL86_RS07350 (CE91St28_14480) 1521772..1522866 + 1095 WP_244388272.1 phage minor head protein -
MWL86_RS07355 (CE91St28_14490) 1522883..1523167 + 285 WP_244388273.1 PGDYG domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1481784..1547747 65963


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10160.65 Da        Isoelectric Point: 8.8648

>T40438 WP_244388268.1 NZ_AP025585:c1518240-1517980 [Pyramidobacter piscolens]
MNKLWSDIAWDEYLEWQSVDKKAVKKINALIKDIERNGVSKGIGKPELLRYINGWSREIDKKNRLVYRIDENGFLFIASC
KGHYED

Download         Length: 261 bp

>T40438 NZ_AP025585:c1518240-1517980 [Pyramidobacter piscolens]
ATGAATAAGCTCTGGTCGGACATAGCGTGGGATGAATACCTTGAATGGCAATCCGTAGACAAGAAAGCCGTCAAGAAAAT
CAACGCGCTGATCAAGGACATCGAACGGAACGGAGTATCCAAGGGCATCGGCAAGCCGGAACTGCTGCGCTACATCAACG
GCTGGAGCCGCGAGATCGACAAAAAGAACCGCCTCGTGTACCGAATCGACGAAAACGGATTTCTTTTTATCGCCTCGTGC
AAAGGGCATTACGAGGATTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9323.58 Da        Isoelectric Point: 5.1297

>AT40438 WP_244388269.1 NZ_AP025585:c1518494-1518246 [Pyramidobacter piscolens]
MLAVSYSTIRTKLKDYCDAAVNNDETIIVTRKNEENVVLLSLDSYNRLMKSLRNAEYVAKLDRAFKQLEAGGGKEHELIE
TD

Download         Length: 249 bp

>AT40438 NZ_AP025585:c1518494-1518246 [Pyramidobacter piscolens]
ATGTTAGCAGTGAGCTACTCGACCATACGGACGAAGCTTAAGGACTACTGCGATGCCGCAGTCAACAACGATGAAACCAT
CATCGTTACCAGAAAGAACGAAGAAAACGTCGTACTGCTGAGCCTCGACAGCTATAACCGCCTGATGAAGAGCCTCCGCA
ACGCCGAATACGTCGCCAAGCTCGACCGCGCGTTCAAACAGCTGGAAGCCGGTGGCGGCAAGGAACATGAGCTTATCGAA
ACGGACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References