Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1477028..1477593 Replicon chromosome
Accession NZ_AP025585
Organism Pyramidobacter piscolens strain CE91-St28

Toxin (Protein)


Gene name relE Uniprot ID D1Y1L2
Locus tag MWL86_RS07015 Protein ID WP_009163744.1
Coordinates 1477303..1477593 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D1Y1L3
Locus tag MWL86_RS07010 Protein ID WP_009163745.1
Coordinates 1477028..1477306 (+) Length 93 a.a.

Genomic Context


MWL86_RS06980MWL86_RS06985MWL86_RS06990MWL86_RS06995MWL86_RS07000MWL86_RS07005MWL86_RS07010MWL86_RS07015MWL86_RS07020MWL86_RS07025MWL86_RS07030MWL86_RS07035
Location: 1472414..1472851 (438 bp)
Type: Others
Protein ID: WP_009163751.1
Location: 1472933..1474855 (1923 bp)
Type: Others
Protein ID: WP_244388210.1
Location: 1475142..1475450 (309 bp)
Type: Others
Protein ID: WP_009163749.1
Location: 1475447..1475791 (345 bp)
Type: Others
Protein ID: WP_244388211.1
Location: 1475808..1475960 (153 bp)
Type: Others
Protein ID: WP_244388212.1
Location: 1476276..1476620 (345 bp)
Type: Others
Protein ID: WP_009163746.1
Location: 1477028..1477306 (279 bp)
Type: Antitoxin
Protein ID: WP_009163745.1
Location: 1477303..1477593 (291 bp)
Type: Toxin
Protein ID: WP_009163744.1
Location: 1478076..1478594 (519 bp)
Type: Others
Protein ID: WP_244388213.1
Location: 1478622..1478822 (201 bp)
Type: Others
Protein ID: WP_009163741.1
Location: 1478850..1479206 (357 bp)
Type: Others
Protein ID: WP_009163740.1
Location: 1479345..1480388 (1044 bp)
Type: Others
Protein ID: WP_244388214.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MWL86_RS06980 (CE91St28_13730)1472414..1472851+438WP_009163751.1dUTP diphosphatase-
MWL86_RS06985 (CE91St28_13740)1472933..1474855+1923WP_244388210.1threonine--tRNA ligase-
MWL86_RS06990 (CE91St28_13750)1475142..1475450+309WP_009163749.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
MWL86_RS06995 (CE91St28_13760)1475447..1475791+345WP_244388211.1type II toxin-antitoxin system RelE/ParE family toxin-
MWL86_RS07000 (CE91St28_13770)1475808..1475960+153WP_244388212.1hypothetical protein-
MWL86_RS07005 (CE91St28_13780)1476276..1476620+345WP_009163746.1hypothetical protein-
MWL86_RS07010 (CE91St28_13790)1477028..1477306+279WP_009163745.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
MWL86_RS07015 (CE91St28_13800)1477303..1477593+291WP_009163744.1type II toxin-antitoxin system YafQ family toxinToxin
MWL86_RS07020 (CE91St28_13810)1478076..1478594+519WP_244388213.1translation initiation factor IF-3-
MWL86_RS07025 (CE91St28_13820)1478622..1478822+201WP_009163741.150S ribosomal protein L35-
MWL86_RS07030 (CE91St28_13830)1478850..1479206+357WP_009163740.150S ribosomal protein L20-
MWL86_RS07035 (CE91St28_13840)1479345..1480388+1044WP_244388214.1phenylalanine--tRNA ligase subunit alpha-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-95)

Antitoxin

(4-90)


Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 11092.11 Da        Isoelectric Point: 10.0372

>T40437 WP_009163744.1 NZ_AP025585:1477303-1477593 [Pyramidobacter piscolens]
VRQTKLTVKLTTAFKKDYKLAMKRGLKLELLDAVIEQLAMGKVLPKIYRDHELAGSWKGHRECHILSDWLLIYRIEESVL
VLTISRTGTHGDLFDK

Download         Length: 291 bp

>T40437 NZ_AP025585:1477303-1477593 [Pyramidobacter piscolens]
GTGAGACAGACAAAGCTGACCGTCAAACTGACCACGGCATTTAAGAAGGACTACAAGCTCGCAATGAAGCGGGGATTAAA
ACTCGAACTTCTGGATGCCGTGATCGAACAGCTTGCCATGGGAAAGGTTCTGCCGAAGATCTACAGGGATCATGAGCTGG
CCGGAAGCTGGAAAGGACACAGGGAATGCCATATCCTCTCCGATTGGCTTTTGATCTATCGGATTGAAGAAAGCGTGCTG
GTGCTGACTATCTCCCGAACGGGAACGCACGGCGACCTGTTTGATAAATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10176.64 Da        Isoelectric Point: 4.5720

>AT40437 WP_009163745.1 NZ_AP025585:1477028-1477306 [Pyramidobacter piscolens]
MAGTTTNISIRMDSDLKAQADALFGELGMNLTTAFNIFVRQSLREGGIPFDICLHQPRQETIAAMLEAERIAKDPSVKGY
TDLDELFADLKK

Download         Length: 279 bp

>AT40437 NZ_AP025585:1477028-1477306 [Pyramidobacter piscolens]
ATGGCTGGAACAACTACCAATATCAGCATCCGTATGGACAGTGACTTGAAAGCACAGGCAGACGCCTTATTCGGTGAGCT
TGGCATGAATCTTACGACGGCTTTCAACATCTTTGTGCGTCAGTCTCTCCGTGAGGGGGGGATTCCCTTTGATATCTGCC
TCCATCAGCCACGCCAGGAGACGATTGCCGCGATGCTGGAAGCGGAGAGGATTGCGAAAGACCCGTCAGTAAAGGGTTAT
ACCGACCTTGACGAGCTGTTCGCGGACCTTAAAAAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBD1Y1L2


Antitoxin

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Source
ID
Structure
AlphaFold DBD1Y1L3

References