Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higB-toxA/Tad-couple_hipB |
| Location | 976212..976644 | Replicon | chromosome |
| Accession | NZ_AP025585 | ||
| Organism | Pyramidobacter piscolens strain CE91-St28 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | MWL86_RS04505 | Protein ID | WP_244389515.1 |
| Coordinates | 976212..976373 (+) | Length | 54 a.a. |
Antitoxin (Protein)
| Gene name | toxA | Uniprot ID | - |
| Locus tag | MWL86_RS04510 | Protein ID | WP_040550454.1 |
| Coordinates | 976360..976644 (+) | Length | 95 a.a. |
Genomic Context
Location: 971433..971912 (480 bp)
Type: Others
Protein ID: WP_009164470.1
Type: Others
Protein ID: WP_009164470.1
Location: 971909..972841 (933 bp)
Type: Others
Protein ID: WP_244389338.1
Type: Others
Protein ID: WP_244389338.1
Location: 972877..973404 (528 bp)
Type: Others
Protein ID: WP_009164468.1
Type: Others
Protein ID: WP_009164468.1
Location: 973479..974372 (894 bp)
Type: Others
Protein ID: WP_009164467.1
Type: Others
Protein ID: WP_009164467.1
Location: 974411..975244 (834 bp)
Type: Others
Protein ID: WP_040550479.1
Type: Others
Protein ID: WP_040550479.1
Location: 975259..975645 (387 bp)
Type: Others
Protein ID: WP_009164465.1
Type: Others
Protein ID: WP_009164465.1
Location: 976212..976373 (162 bp)
Type: Toxin
Protein ID: WP_244389515.1
Type: Toxin
Protein ID: WP_244389515.1
Location: 976360..976644 (285 bp)
Type: Antitoxin
Protein ID: WP_040550454.1
Type: Antitoxin
Protein ID: WP_040550454.1
Location: 977246..977485 (240 bp)
Type: Others
Protein ID: WP_244389339.1
Type: Others
Protein ID: WP_244389339.1
Location: 977479..977808 (330 bp)
Type: Others
Protein ID: WP_244389340.1
Type: Others
Protein ID: WP_244389340.1
Location: 979103..980896 (1794 bp)
Type: Others
Protein ID: WP_244389342.1
Type: Others
Protein ID: WP_244389342.1
Location: 980893..981486 (594 bp)
Type: Others
Protein ID: WP_244389343.1
Type: Others
Protein ID: WP_244389343.1
Location: 978073..978957 (885 bp)
Type: Others
Protein ID: WP_244389341.1
Type: Others
Protein ID: WP_244389341.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MWL86_RS04470 (CE91St28_08940) | 971433..971912 | + | 480 | WP_009164470.1 | peptide deformylase | - |
| MWL86_RS04475 (CE91St28_08950) | 971909..972841 | + | 933 | WP_244389338.1 | methionyl-tRNA formyltransferase | - |
| MWL86_RS04480 (CE91St28_08960) | 972877..973404 | + | 528 | WP_009164468.1 | NUDIX hydrolase | - |
| MWL86_RS04485 (CE91St28_08970) | 973479..974372 | + | 894 | WP_009164467.1 | tyrosine-type recombinase/integrase | - |
| MWL86_RS04490 (CE91St28_08980) | 974411..975244 | + | 834 | WP_040550479.1 | purine-nucleoside phosphorylase | - |
| MWL86_RS04495 (CE91St28_08990) | 975259..975645 | + | 387 | WP_009164465.1 | J domain-containing protein | - |
| MWL86_RS04505 | 976212..976373 | + | 162 | WP_244389515.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| MWL86_RS04510 (CE91St28_09000) | 976360..976644 | + | 285 | WP_040550454.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| MWL86_RS04515 (CE91St28_09010) | 977246..977485 | + | 240 | WP_244389339.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| MWL86_RS04520 (CE91St28_09020) | 977479..977808 | + | 330 | WP_244389340.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| MWL86_RS04525 (CE91St28_09030) | 978073..978957 | - | 885 | WP_244389341.1 | LysR family transcriptional regulator | - |
| MWL86_RS04530 (CE91St28_09040) | 979103..980896 | + | 1794 | WP_244389342.1 | indolepyruvate ferredoxin oxidoreductase subunit alpha | - |
| MWL86_RS04535 (CE91St28_09050) | 980893..981486 | + | 594 | WP_244389343.1 | indolepyruvate oxidoreductase subunit beta | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 54 a.a. Molecular weight: 6320.25 Da Isoelectric Point: 8.8959
>T40435 WP_244389515.1 NZ_AP025585:976212-976373 [Pyramidobacter piscolens]
MRDRILFAAWVDGGFVLLHAFVKKTQKTPRREIEQAKRELADFVERSVHHEQE
MRDRILFAAWVDGGFVLLHAFVKKTQKTPRREIEQAKRELADFVERSVHHEQE
Download Length: 162 bp
>T40435 NZ_AP025585:976212-976373 [Pyramidobacter piscolens]
CTGCGCGACCGAATTCTTTTTGCCGCGTGGGTTGACGGCGGTTTTGTGCTGCTTCATGCTTTCGTGAAGAAGACCCAGAA
GACGCCGCGTCGCGAAATCGAGCAGGCTAAAAGGGAACTGGCGGACTTCGTCGAAAGGAGCGTTCACCATGAACAGGAAT
AG
CTGCGCGACCGAATTCTTTTTGCCGCGTGGGTTGACGGCGGTTTTGTGCTGCTTCATGCTTTCGTGAAGAAGACCCAGAA
GACGCCGCGTCGCGAAATCGAGCAGGCTAAAAGGGAACTGGCGGACTTCGTCGAAAGGAGCGTTCACCATGAACAGGAAT
AG
Antitoxin
Download Length: 95 a.a. Molecular weight: 10332.11 Da Isoelectric Point: 8.7131
>AT40435 WP_040550454.1 NZ_AP025585:976360-976644 [Pyramidobacter piscolens]
MNRNSAVGMSLEELERELLTPEEIAESNVRVAIIGELIKARQARGLTQRKLEELSGVKQPVIARMEKGTTNPQLDTVIKL
LAPLGKTLAVVDLK
MNRNSAVGMSLEELERELLTPEEIAESNVRVAIIGELIKARQARGLTQRKLEELSGVKQPVIARMEKGTTNPQLDTVIKL
LAPLGKTLAVVDLK
Download Length: 285 bp
>AT40435 NZ_AP025585:976360-976644 [Pyramidobacter piscolens]
ATGAACAGGAATAGCGCTGTGGGCATGAGCCTTGAAGAACTGGAACGGGAACTGCTGACGCCGGAAGAGATTGCCGAAAG
CAACGTCCGCGTGGCCATTATCGGCGAACTCATCAAGGCCCGTCAGGCGCGCGGCCTCACGCAAAGGAAGCTTGAAGAGC
TGTCCGGCGTGAAGCAGCCCGTCATTGCCAGAATGGAAAAGGGTACGACCAATCCCCAGCTGGACACGGTGATAAAACTG
CTGGCCCCCTTGGGGAAGACCTTGGCCGTCGTAGACCTGAAATGA
ATGAACAGGAATAGCGCTGTGGGCATGAGCCTTGAAGAACTGGAACGGGAACTGCTGACGCCGGAAGAGATTGCCGAAAG
CAACGTCCGCGTGGCCATTATCGGCGAACTCATCAAGGCCCGTCAGGCGCGCGGCCTCACGCAAAGGAAGCTTGAAGAGC
TGTCCGGCGTGAAGCAGCCCGTCATTGCCAGAATGGAAAAGGGTACGACCAATCCCCAGCTGGACACGGTGATAAAACTG
CTGGCCCCCTTGGGGAAGACCTTGGCCGTCGTAGACCTGAAATGA