Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 920209..920743 Replicon chromosome
Accession NZ_AP025585
Organism Pyramidobacter piscolens strain CE91-St28

Toxin (Protein)


Gene name relE Uniprot ID D1Y3V1
Locus tag MWL86_RS04235 Protein ID WP_009164532.1
Coordinates 920468..920743 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MWL86_RS04230 Protein ID WP_040550473.1
Coordinates 920209..920475 (+) Length 89 a.a.

Genomic Context

MWL86_RS04220MWL86_RS04230MWL86_RS04235MWL86_RS04245MWL86_RS04250MWL86_RS04225MWL86_RS12865
Location: 917684..917911 (228 bp)
Type: Others
Protein ID: WP_156797436.1
Location: 920209..920475 (267 bp)
Type: Antitoxin
Protein ID: WP_040550473.1
Location: 920468..920743 (276 bp)
Type: Toxin
Protein ID: WP_009164532.1
Location: 921768..923018 (1251 bp)
Type: Others
Protein ID: WP_244389311.1
Location: 923046..924887 (1842 bp)
Type: Others
Protein ID: WP_244389312.1
Location: 917978..919618 (1641 bp)
Type: Others
Protein ID: WP_244389310.1
Location: 921142..921345 (204 bp)
Type: Others
Protein ID: WP_279612192.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MWL86_RS04220 (CE91St28_08450)917684..917911+228WP_156797436.1hypothetical protein-
MWL86_RS04225 (CE91St28_08460)917978..919618-1641WP_244389310.1IS1634 family transposase-
MWL86_RS04230 (CE91St28_08470)920209..920475+267WP_040550473.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
MWL86_RS04235 (CE91St28_08480)920468..920743+276WP_009164532.1type II toxin-antitoxin system YafQ family toxinToxin
MWL86_RS12865 (CE91St28_08490)921142..921345-204WP_279612192.1GDP-mannose 4,6-dehydratase-
MWL86_RS04245 (CE91St28_08500)921768..923018+1251WP_244389311.1nucleotide sugar dehydrogenase-
MWL86_RS04250 (CE91St28_08510)923046..924887+1842WP_244389312.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-86)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10781.26 Da        Isoelectric Point: 6.4762

>T40434 WP_009164532.1 NZ_AP025585:920468-920743 [Pyramidobacter piscolens]
MLNLRYQSAFKRDYKRIRKRGYDVQRLESIIEMLAKEQVLPEECRDHDLGGTWSGFRECHIEPDWLLVYTIDHNDLVLVL
SRTGSHSDLFG

Download         Length: 276 bp

>T40434 NZ_AP025585:920468-920743 [Pyramidobacter piscolens]
ATGCTTAACCTCAGATATCAGTCGGCCTTCAAGCGCGACTACAAGCGTATCCGCAAACGGGGGTACGATGTTCAGCGGCT
GGAAAGCATCATCGAGATGCTCGCCAAAGAGCAGGTGCTCCCCGAGGAGTGCCGCGACCACGATTTGGGCGGCACTTGGT
CGGGGTTCCGCGAGTGCCATATCGAGCCGGACTGGCTGCTCGTCTACACCATCGACCATAACGATTTGGTCTTGGTCCTC
AGCCGTACCGGTTCGCACAGCGATCTGTTCGGATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9868.28 Da        Isoelectric Point: 6.3196

>AT40434 WP_040550473.1 NZ_AP025585:920209-920475 [Pyramidobacter piscolens]
MATTNVTVRMDENLKADFEEMLADFGLNTSVAINIFARQVVYERRIPFVIARDRPNAATRAAMEDARARRGLSKTFSSVK
DLMADLDA

Download         Length: 267 bp

>AT40434 NZ_AP025585:920209-920475 [Pyramidobacter piscolens]
ATGGCGACAACCAACGTCACCGTAAGGATGGACGAAAATCTGAAAGCCGATTTCGAAGAAATGCTCGCCGACTTCGGGCT
GAATACGTCGGTGGCCATTAACATCTTCGCGCGCCAAGTCGTGTACGAGCGGCGGATCCCGTTCGTGATTGCGCGCGACC
GCCCCAACGCCGCGACGCGTGCGGCCATGGAAGACGCCCGCGCGCGCCGCGGCCTGAGCAAGACCTTCTCGTCCGTGAAA
GACCTGATGGCCGATCTCGATGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBD1Y3V1

Antitoxin

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Source
ID
Structure
No matching records found

References