Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 289533..290101 Replicon chromosome
Accession NZ_AP025564
Organism Raoultibacter timonensis strain CE91-St30

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MWL89_RS01025 Protein ID WP_244411403.1
Coordinates 289533..289823 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MWL89_RS01030 Protein ID WP_244411404.1
Coordinates 289826..290101 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MWL89_RS00990 (CE91St30_02030) 284937..285233 - 297 WP_244411396.1 hypothetical protein -
MWL89_RS00995 (CE91St30_02040) 285319..285600 - 282 WP_244411397.1 hypothetical protein -
MWL89_RS01000 (CE91St30_02060) 285727..286044 - 318 WP_244411398.1 integration host factor, actinobacterial type -
MWL89_RS01005 (CE91St30_02070) 286041..286517 - 477 WP_244411399.1 hypothetical protein -
MWL89_RS01010 (CE91St30_02080) 286549..286980 - 432 WP_244411400.1 single-stranded DNA-binding protein -
MWL89_RS01015 (CE91St30_02090) 287028..287309 - 282 WP_244411401.1 hypothetical protein -
MWL89_RS01020 (CE91St30_02100) 287299..288087 - 789 WP_244411402.1 ParA family protein -
MWL89_RS01025 (CE91St30_02110) 289533..289823 - 291 WP_244411403.1 type II toxin-antitoxin system YafQ family toxin Toxin
MWL89_RS01030 (CE91St30_02120) 289826..290101 - 276 WP_244411404.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MWL89_RS01035 (CE91St30_02130) 290221..290400 + 180 WP_244411405.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(8-74)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11108.82 Da        Isoelectric Point: 7.7815

>T40426 WP_244411403.1 NZ_AP025564:c289823-289533 [Raoultibacter timonensis]
MLAAKFDERFKRDLKRLDKKHVDDKPLEAVIALILENTPESISELKRCRNMYTLSGKWSGSNECHVCNAGDWLLIWSVKG
DMAVMQRTGTHDELFR

Download         Length: 291 bp

>T40426 NZ_AP025564:c289823-289533 [Raoultibacter timonensis]
ATGCTAGCTGCAAAATTTGACGAGAGGTTCAAACGCGACCTCAAGCGCCTTGACAAGAAACATGTGGACGACAAGCCTCT
GGAAGCCGTCATCGCGCTCATCCTCGAGAACACCCCCGAGTCCATATCGGAGCTGAAAAGGTGCCGCAACATGTACACGC
TGTCCGGCAAGTGGTCGGGCAGCAACGAATGCCACGTGTGCAACGCCGGGGACTGGCTTCTCATCTGGAGCGTGAAGGGC
GATATGGCGGTCATGCAGAGAACCGGAACGCACGACGAGCTGTTCAGATAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10310.56 Da        Isoelectric Point: 4.7225

>AT40426 WP_244411404.1 NZ_AP025564:c290101-289826 [Raoultibacter timonensis]
MASVTYPIWVDDALKGDAARVAEHYGFDLASVTRAFWKQMVRTESIPLTLRSEEPNEESLEAIRETEEIFASHRPGEGFK
TARELLDAARK

Download         Length: 276 bp

>AT40426 NZ_AP025564:c290101-289826 [Raoultibacter timonensis]
ATGGCATCCGTGACTTATCCCATATGGGTCGACGATGCGCTCAAGGGCGACGCGGCACGCGTCGCCGAGCATTACGGCTT
CGACCTCGCCAGCGTGACAAGAGCTTTCTGGAAGCAGATGGTCCGCACCGAGAGCATCCCGCTCACGCTGCGCAGCGAGG
AGCCCAACGAGGAGAGCCTGGAGGCGATCAGGGAAACGGAAGAGATCTTCGCAAGCCATCGACCGGGCGAAGGCTTCAAA
ACCGCCCGAGAGCTCCTTGACGCTGCGAGGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References