Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 5281164..5281695 Replicon chromosome
Accession NZ_AP025556
Organism Delftia lacustris strain HQS1

Toxin (Protein)


Gene name relE Uniprot ID I2ALI9
Locus tag HQS1_RS24065 Protein ID WP_011114071.1
Coordinates 5281164..5281445 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID I2ALI8
Locus tag HQS1_RS24070 Protein ID WP_011114070.1
Coordinates 5281432..5281695 (-) Length 88 a.a.

Genomic Context

HQS1_RS24055HQS1_RS24060HQS1_RS24075HQS1_RS24080HQS1_RS24085HQS1_RS24090HQS1_RS24095HQS1_RS24100HQS1_RS24105HQS1_RS24110HQS1_RS24115HQS1_RS24065HQS1_RS24070
Location: 5276736..5277518 (783 bp)
Type: Others
Protein ID: WP_244451713.1
Location: 5277692..5280019 (2328 bp)
Type: Others
Protein ID: Protein_4732
Location: 5281868..5282296 (429 bp)
Type: Others
Protein ID: WP_011114069.1
Location: 5282341..5282559 (219 bp)
Type: Others
Protein ID: WP_012478187.1
Location: 5282571..5283779 (1209 bp)
Type: Others
Protein ID: WP_011114068.1
Location: 5283796..5284053 (258 bp)
Type: Others
Protein ID: WP_011114067.1
Location: 5284211..5284447 (237 bp)
Type: Others
Protein ID: WP_011114066.1
Location: 5284656..5284982 (327 bp)
Type: Others
Protein ID: WP_011114065.1
Location: 5284984..5285313 (330 bp)
Type: Others
Protein ID: WP_011114064.1
Location: 5285420..5285728 (309 bp)
Type: Others
Protein ID: WP_011114062.1
Location: 5285725..5286345 (621 bp)
Type: Others
Protein ID: WP_244387032.1
Location: 5281164..5281445 (282 bp)
Type: Toxin
Protein ID: WP_011114071.1
Location: 5281432..5281695 (264 bp)
Type: Antitoxin
Protein ID: WP_011114070.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HQS1_RS24055 (HQS1_47560)5276736..5277518+783WP_244451713.1IS21-like element helper ATPase IstB-
HQS1_RS24060 (HQS1_47570)5277692..5280019+2328Protein_4732Tn3-like element IS1071 family transposase-
HQS1_RS24065 (HQS1_47580)5281164..5281445-282WP_011114071.1type II toxin-antitoxin system YafQ family toxinToxin
HQS1_RS24070 (HQS1_47590)5281432..5281695-264WP_011114070.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
HQS1_RS24075 (HQS1_47600)5281868..5282296+429WP_011114069.1antirestriction protein-
HQS1_RS24080 (HQS1_47610)5282341..5282559+219WP_012478187.1hypothetical protein-
HQS1_RS24085 (HQS1_47620)5282571..5283779+1209WP_011114068.1hypothetical protein-
HQS1_RS24090 (HQS1_47630)5283796..5284053+258WP_011114067.1transcriptional repressor KorC-
HQS1_RS24095 (HQS1_47640)5284211..5284447+237WP_011114066.1stable inheritance protein KleA-
HQS1_RS24100 (HQS1_47650)5284656..5284982+327WP_011114065.1KleE stable inheritance protein-
HQS1_RS24105 (HQS1_47660)5284984..5285313+330WP_011114064.1DUF2761 domain-containing protein-
HQS1_RS24110 (HQS1_47670)5285420..5285728+309WP_011114062.1transcriptional regulator KorA-
HQS1_RS24115 (HQS1_47680)5285725..5286345+621WP_244387032.1ParA family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--5202835..5400932198097


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10743.19 Da        Isoelectric Point: 7.4750

>T40421 WP_011114071.1 NZ_AP025556:c5281445-5281164 [Delftia lacustris]
MRQIERTGQFKRDYKREAKGQHRATLDADLVPVLVALADDQPLEPRHRDHALTGDWKDHRDCHVKPDLVLIYQKPDADTL
RLVRLGSHSELGL

Download         Length: 282 bp

>T40421 NZ_AP025556:c5281445-5281164 [Delftia lacustris]
ATGCGGCAGATTGAGCGCACCGGCCAGTTCAAGCGCGACTACAAGCGCGAGGCGAAAGGGCAGCACCGGGCCACGCTCGA
CGCCGACCTGGTGCCCGTCCTGGTCGCGCTCGCCGACGACCAGCCGCTGGAACCTCGGCACCGCGACCACGCGCTGACCG
GGGACTGGAAGGATCACCGGGATTGCCACGTCAAGCCCGACCTGGTGCTGATCTACCAGAAGCCCGACGCCGACACGCTG
CGCCTGGTGCGCCTCGGCTCTCACTCCGAACTCGGCTTGTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9255.82 Da        Isoelectric Point: 5.7905

>AT40421 WP_011114070.1 NZ_AP025556:c5281695-5281432 [Delftia lacustris]
MAANQLVQTRIDGAIKEEAAAVLAAMGLTVSDAVRLLLTKVAQDKALPFEPLIPNATTIEAMKEARKGKLPRFATVNDLM
ADLHAAD

Download         Length: 264 bp

>AT40421 NZ_AP025556:c5281695-5281432 [Delftia lacustris]
ATGGCTGCAAACCAGCTCGTACAAACGCGCATCGACGGCGCGATCAAGGAAGAAGCGGCGGCCGTCCTGGCCGCGATGGG
CCTTACCGTGTCCGACGCGGTGCGGCTGCTGCTCACGAAGGTGGCCCAGGACAAGGCGCTGCCCTTCGAGCCGCTGATTC
CGAACGCCACCACCATCGAGGCGATGAAGGAAGCCCGCAAGGGCAAGCTGCCGCGCTTCGCCACCGTCAACGATCTGATG
GCCGATCTGCATGCGGCAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1U9V4I5

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1U9V3I2

References