Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 903021..903601 Replicon chromosome
Accession NZ_AP025556
Organism Delftia lacustris strain HQS1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HQS1_RS04085 Protein ID WP_034363334.1
Coordinates 903021..903401 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A9C0Y1
Locus tag HQS1_RS04090 Protein ID WP_012207613.1
Coordinates 903398..903601 (-) Length 68 a.a.

Genomic Context

HQS1_RS04065HQS1_RS04070HQS1_RS04080HQS1_RS04095HQS1_RS04100HQS1_RS04075HQS1_RS04085HQS1_RS04090
Location: 898344..899585 (1242 bp)
Type: Others
Protein ID: WP_016448371.1
Location: 899582..900340 (759 bp)
Type: Others
Protein ID: WP_016452684.1
Location: 902190..902942 (753 bp)
Type: Others
Protein ID: WP_034363332.1
Location: 903752..904564 (813 bp)
Type: Others
Protein ID: WP_034363336.1
Location: 904673..906349 (1677 bp)
Type: Others
Protein ID: WP_034363338.1
Location: 900375..901961 (1587 bp)
Type: Others
Protein ID: WP_034363331.1
Location: 903021..903401 (381 bp)
Type: Toxin
Protein ID: WP_034363334.1
Location: 903398..903601 (204 bp)
Type: Antitoxin
Protein ID: WP_012207613.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HQS1_RS04065 (HQS1_07990)898344..899585+1242WP_016448371.1ABC transporter substrate-binding protein-
HQS1_RS04070 (HQS1_08000)899582..900340+759WP_016452684.1ABC transporter permease-
HQS1_RS04075 (HQS1_08010)900375..901961-1587WP_034363331.1Ig-like domain repeat protein-
HQS1_RS04080 (HQS1_08020)902190..902942+753WP_034363332.1helix-turn-helix transcriptional regulator-
HQS1_RS04085 (HQS1_08030)903021..903401-381WP_034363334.1type II toxin-antitoxin system VapC family toxinToxin
HQS1_RS04090 (HQS1_08040)903398..903601-204WP_012207613.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
HQS1_RS04095 (HQS1_08050)903752..904564+813WP_034363336.1glucose 1-dehydrogenase-
HQS1_RS04100 (HQS1_08060)904673..906349+1677WP_034363338.1VRR-NUC domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13903.28 Da        Isoelectric Point: 9.4293

>T40418 WP_034363334.1 NZ_AP025556:c903401-903021 [Delftia lacustris]
MNPVLVDTSVWIDHFRQGNPHLAQLLQQDMALMHPLVLGELACGTPPARARTLADLQRLKPARQASMREVLALIEREQLF
GLGCGLVDITLLASALISSGASLWSRDRRLHALAQRFGIAYRSVLP

Download         Length: 381 bp

>T40418 NZ_AP025556:c903401-903021 [Delftia lacustris]
ATGAATCCCGTTCTGGTCGATACCTCGGTCTGGATCGATCACTTCAGGCAGGGCAATCCTCACCTGGCGCAGTTGCTGCA
GCAAGACATGGCGCTCATGCATCCCCTGGTGCTGGGTGAACTGGCTTGCGGCACGCCACCGGCACGCGCACGCACGCTCG
CGGACCTTCAGCGGCTCAAGCCTGCCCGGCAGGCCAGCATGCGCGAAGTGCTGGCCTTGATAGAGCGCGAGCAACTCTTT
GGTCTGGGCTGCGGTCTGGTGGACATCACGCTCCTGGCCTCGGCACTCATATCTTCAGGTGCCAGCCTGTGGTCGCGAGA
CAGGCGCCTGCACGCGCTGGCCCAGCGGTTTGGCATTGCCTACCGGAGCGTCTTGCCGTAG

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7485.58 Da        Isoelectric Point: 4.5702

>AT40418 WP_012207613.1 NZ_AP025556:c903601-903398 [Delftia lacustris]
MRTTVTIDDALYEEALELAEPEMDKADLFREAVKTFVRVQAAKRLAALGGSAPDMREIPRRPQGIEP

Download         Length: 204 bp

>AT40418 NZ_AP025556:c903601-903398 [Delftia lacustris]
ATGAGAACCACGGTCACCATCGACGACGCCTTGTACGAGGAAGCGCTGGAGCTGGCGGAGCCAGAAATGGACAAGGCCGA
CCTGTTTCGCGAAGCCGTCAAGACTTTCGTGAGAGTGCAGGCGGCCAAGCGTCTGGCCGCGCTGGGAGGCTCCGCACCGG
ACATGCGGGAGATTCCCCGTCGCCCACAGGGCATCGAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA9C0Y1

References