Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1301378..1302013 Replicon chromosome
Accession NZ_AP025517
Organism Pandoraea sp. NE5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PanNE5_RS06090 Protein ID WP_017233795.1
Coordinates 1301378..1301797 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PanNE5_RS06095 Protein ID WP_130024507.1
Coordinates 1301813..1302013 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PanNE5_RS06070 (PanNE5_12170) 1296643..1296840 - 198 WP_017233791.1 YbdD/YjiX family protein -
PanNE5_RS06075 (PanNE5_12180) 1296857..1298923 - 2067 WP_017233792.1 carbon starvation CstA family protein -
PanNE5_RS06080 (PanNE5_12190) 1299289..1300674 + 1386 WP_017233793.1 cache domain-containing protein -
PanNE5_RS06085 (PanNE5_12200) 1300671..1301303 + 633 WP_017233794.1 response regulator transcription factor -
PanNE5_RS06090 (PanNE5_12210) 1301378..1301797 - 420 WP_017233795.1 type II toxin-antitoxin system VapC family toxin Toxin
PanNE5_RS06095 (PanNE5_12220) 1301813..1302013 - 201 WP_130024507.1 DNA-binding protein Antitoxin
PanNE5_RS06100 (PanNE5_12230) 1302265..1304154 - 1890 WP_261939415.1 phosphoenolpyruvate carboxykinase (GTP) -
PanNE5_RS06105 (PanNE5_12240) 1304717..1305727 + 1011 WP_130024506.1 D-2-hydroxyacid dehydrogenase family protein -
PanNE5_RS06110 (PanNE5_12250) 1305751..1306599 - 849 WP_261939416.1 patatin-like phospholipase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16029.49 Da        Isoelectric Point: 9.6766

>T40351 WP_017233795.1 NZ_AP025517:c1301797-1301378 [Pandoraea sp. NE5]
MYLLDTNVISECRKCGGGDEGVQRFIRRTDRDQSPRFLSVITLGELQRGVKVLRHRNDARQAVLIEAWLEKLKRDYAREI
LPVDQTICNVWARLRVPHSEHPIDKLIAATALVHRLVVVTRNVRDFSSTGVEVYNPFVH

Download         Length: 420 bp

>T40351 NZ_AP025517:c1301797-1301378 [Pandoraea sp. NE5]
ATGTATTTACTCGATACGAACGTTATTAGCGAGTGTCGGAAATGCGGGGGCGGTGACGAAGGGGTTCAGCGCTTTATCCG
TCGGACCGATCGTGATCAATCACCGCGCTTTCTTTCGGTCATCACGCTGGGAGAACTACAGCGTGGTGTGAAAGTCCTTC
GGCACCGGAATGATGCGCGACAGGCGGTGCTGATCGAGGCATGGCTCGAAAAGCTGAAACGCGATTACGCGCGAGAGATT
TTGCCGGTGGACCAGACGATCTGTAACGTTTGGGCACGTCTACGCGTGCCCCATTCCGAGCACCCCATCGACAAGTTGAT
CGCTGCCACTGCGCTGGTGCATCGGCTTGTCGTGGTCACGCGCAACGTGAGGGATTTTTCCAGTACCGGCGTAGAGGTAT
ACAACCCATTTGTGCACTGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7378.54 Da        Isoelectric Point: 4.3021

>AT40351 WP_130024507.1 NZ_AP025517:c1302013-1301813 [Pandoraea sp. NE5]
MMLIEGIDEPLMRSIRSRAAMYGRTPEEEVLTILDNVARVPGFRSLGEALLAMPNVGLDSDFERIN

Download         Length: 201 bp

>AT40351 NZ_AP025517:c1302013-1301813 [Pandoraea sp. NE5]
ATGATGTTGATCGAAGGTATTGACGAACCGCTCATGCGATCGATTCGGTCGCGTGCGGCCATGTACGGGAGAACCCCGGA
GGAAGAAGTGCTGACGATTCTGGATAACGTGGCGCGGGTTCCGGGGTTTCGCTCGCTGGGGGAAGCACTGTTGGCCATGC
CGAATGTCGGACTGGACAGCGATTTTGAACGTATCAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References