Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 359419..359978 | Replicon | chromosome |
| Accession | NZ_AP025515 | ||
| Organism | Vibrio toranzoniae strain CECT 7225 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A120DEA8 |
| Locus tag | OCU50_RS15985 | Protein ID | WP_046225271.1 |
| Coordinates | 359700..359978 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | F9RXS2 |
| Locus tag | OCU50_RS15980 | Protein ID | WP_006710667.1 |
| Coordinates | 359419..359703 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OCU50_RS15940 | 355382..355669 | - | 288 | WP_060469701.1 | hypothetical protein | - |
| OCU50_RS15945 | 355856..356344 | + | 489 | WP_060469702.1 | Sbal_3080 family lipoprotein | - |
| OCU50_RS15950 | 356430..356771 | - | 342 | WP_060469703.1 | SH3 domain-containing protein | - |
| OCU50_RS15955 | 356916..357167 | - | 252 | WP_060469704.1 | TIGR03643 family protein | - |
| OCU50_RS15960 | 357281..358105 | - | 825 | WP_235588172.1 | hypothetical protein | - |
| OCU50_RS15965 | 358176..358268 | - | 93 | Protein_288 | DUF3265 domain-containing protein | - |
| OCU50_RS15970 | 358271..358666 | - | 396 | WP_060469705.1 | DUF3465 domain-containing protein | - |
| OCU50_RS15975 | 358862..359083 | + | 222 | WP_060469706.1 | hypothetical protein | - |
| OCU50_RS15980 | 359419..359703 | + | 285 | WP_006710667.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| OCU50_RS15985 | 359700..359978 | + | 279 | WP_046225271.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| OCU50_RS15990 | 360115..360627 | - | 513 | WP_060469826.1 | hypothetical protein | - |
| OCU50_RS15995 | 360656..360772 | - | 117 | WP_100550320.1 | DUF3265 domain-containing protein | - |
| OCU50_RS16000 | 360775..361089 | - | 315 | WP_025787411.1 | hypothetical protein | - |
| OCU50_RS16005 | 361233..361895 | - | 663 | WP_060469825.1 | hypothetical protein | - |
| OCU50_RS16010 | 361871..362029 | - | 159 | WP_244158275.1 | DUF3265 domain-containing protein | - |
| OCU50_RS16015 | 362017..362436 | - | 420 | WP_060469832.1 | GNAT family N-acetyltransferase | - |
| OCU50_RS16020 | 363099..363563 | - | 465 | WP_025534186.1 | hypothetical protein | - |
| OCU50_RS16025 | 363701..363937 | - | 237 | WP_060469827.1 | hypothetical protein | - |
| OCU50_RS16030 | 364146..364367 | + | 222 | WP_065311181.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 357281..388501 | 31220 | |
| - | inside | Integron | - | - | 357281..388501 | 31220 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10808.44 Da Isoelectric Point: 4.3324
>T40348 WP_046225271.1 NZ_AP025515:359700-359978 [Vibrio toranzoniae]
MILWEEESLNDREKIFEFLYDFNPDAADKTDEIIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSAIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAADKTDEIIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSAIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T40348 NZ_AP025515:359700-359978 [Vibrio toranzoniae]
ATGATTTTATGGGAAGAAGAATCGCTAAATGATCGTGAGAAGATCTTTGAGTTTCTTTATGACTTCAACCCTGATGCGGC
AGACAAAACTGACGAAATTATCGAAGCTAAAGTAGAAAATTTACTTGAGCAACCATTAATGGGTGTTCAACGTGATGGTA
TTCGAGGACGATTACTAATTATCCCCGAAATCTCAATGATCGTTTCTTACTGGGTTGACGGCTCAGCGATTCGCGTAATG
CGAGTTCTACACCAGAAGCAAAAATTCCCTACCGACTGA
ATGATTTTATGGGAAGAAGAATCGCTAAATGATCGTGAGAAGATCTTTGAGTTTCTTTATGACTTCAACCCTGATGCGGC
AGACAAAACTGACGAAATTATCGAAGCTAAAGTAGAAAATTTACTTGAGCAACCATTAATGGGTGTTCAACGTGATGGTA
TTCGAGGACGATTACTAATTATCCCCGAAATCTCAATGATCGTTTCTTACTGGGTTGACGGCTCAGCGATTCGCGTAATG
CGAGTTCTACACCAGAAGCAAAAATTCCCTACCGACTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10857.17 Da Isoelectric Point: 8.0515
>AT40348 WP_006710667.1 NZ_AP025515:359419-359703 [Vibrio toranzoniae]
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKALSHDAWLTEQVNLAFEKFDSGKASFVDHDSAKAR
MAERKAKIRSRGQQ
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKALSHDAWLTEQVNLAFEKFDSGKASFVDHDSAKAR
MAERKAKIRSRGQQ
Download Length: 285 bp
>AT40348 NZ_AP025515:359419-359703 [Vibrio toranzoniae]
ATGGACACTCGAATTCAATTTCGTGTTGATGACGAAATCAAACGCTTAGCTCAGCAAATGGCTGAAAGCCAAGGACGCAC
ACTTAGCGATGCTTGCCGTGAACTTACTGAGCAAATGGCTGAACAACAACGCAAAGCATTATCTCACGACGCTTGGTTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAAGCTTCATTTGTTGACCATGACTCAGCAAAAGCGCGA
ATGGCTGAACGAAAAGCAAAGATTCGTAGCCGAGGTCAACAATGA
ATGGACACTCGAATTCAATTTCGTGTTGATGACGAAATCAAACGCTTAGCTCAGCAAATGGCTGAAAGCCAAGGACGCAC
ACTTAGCGATGCTTGCCGTGAACTTACTGAGCAAATGGCTGAACAACAACGCAAAGCATTATCTCACGACGCTTGGTTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAAGCTTCATTTGTTGACCATGACTCAGCAAAAGCGCGA
ATGGCTGAACGAAAAGCAAAGATTCGTAGCCGAGGTCAACAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A120DEA8 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A109D557 |