Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1359540..1360048 Replicon chromosome
Accession NZ_AP025511
Organism Vibrio tasmaniensis strain LMG 20012

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCV44_RS20265 Protein ID WP_139686202.1
Coordinates 1359788..1360048 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OCV44_RS20260 Protein ID WP_139686201.1
Coordinates 1359540..1359791 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV44_RS20220 1355177..1355467 - 291 WP_005377002.1 type II toxin-antitoxin system RelE/ParE family toxin -
OCV44_RS20225 1355457..1355705 - 249 WP_004730320.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OCV44_RS20230 1355780..1355872 + 93 Protein_1141 DUF3265 domain-containing protein -
OCV44_RS20235 1356144..1357168 - 1025 Protein_1142 IS110 family transposase -
OCV44_RS20240 1357335..1357790 + 456 WP_246091860.1 DUF2559 family protein -
OCV44_RS20245 1357783..1358385 + 603 WP_139686199.1 putative adenosine monophosphate-protein transferase Fic -
OCV44_RS20250 1358550..1358900 + 351 WP_139686200.1 cupin domain-containing protein -
OCV44_RS20255 1358933..1359409 - 477 Protein_1146 transposase -
OCV44_RS20260 1359540..1359791 + 252 WP_139686201.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OCV44_RS20265 1359788..1360048 + 261 WP_139686202.1 Txe/YoeB family addiction module toxin Toxin
OCV44_RS20270 1360680..1361177 + 498 WP_139686205.1 DUF2867 domain-containing protein -
OCV44_RS20275 1361311..1361859 + 549 WP_139686204.1 hypothetical protein -
OCV44_RS20280 1362894..1364216 + 1323 WP_261900919.1 IS4-like element ISVbsp1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1352019..1364216 12197
- inside IScluster/Tn - - 1354070..1364216 10146


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10295.77 Da        Isoelectric Point: 8.8610

>T40346 WP_139686202.1 NZ_AP025511:1359788-1360048 [Vibrio tasmaniensis]
MSRMLAWTDEAWDDYLYWQGQDKKTLKRINKLITDAKRLPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAVNDSHLTMI
SCRYHY

Download         Length: 261 bp

>T40346 NZ_AP025511:1359788-1360048 [Vibrio tasmaniensis]
ATGAGTCGAATGTTAGCGTGGACTGATGAAGCGTGGGATGATTATTTATATTGGCAAGGACAGGACAAGAAAACCCTTAA
ACGTATTAATAAGTTAATCACAGATGCAAAGCGTTTACCATTTGAAGGCATTGGCAAACCTGAGCCATTGAAAGAAAACT
TAGCTGGTTTTTGGTCACGCAGGATTGACGATACAAATAGACTAGTTTATGCAGTGAATGATTCACATTTGACGATGATT
TCTTGTCGTTATCACTACTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9335.40 Da        Isoelectric Point: 4.3707

>AT40346 WP_139686201.1 NZ_AP025511:1359540-1359791 [Vibrio tasmaniensis]
MRIVSFTEARNGLKSVLDGVVNDADCTVITRRDSEDAVVMSMDYYNSLMETIYLSRSPANAAHLNKSITQYNEGQTTERD
LLE

Download         Length: 252 bp

>AT40346 NZ_AP025511:1359540-1359791 [Vibrio tasmaniensis]
ATGCGTATAGTTTCTTTTACTGAAGCCAGAAATGGTCTTAAATCTGTTCTTGATGGCGTGGTTAATGATGCAGACTGCAC
AGTCATCACTCGTCGAGATTCTGAAGACGCGGTTGTAATGTCTATGGACTACTACAATAGTTTAATGGAAACGATATATT
TATCACGTTCTCCTGCGAATGCTGCTCACTTAAACAAATCAATTACTCAATACAATGAAGGTCAAACTACGGAAAGAGAT
TTACTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References