Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 276173..276969 Replicon chromosome
Accession NZ_AP025511
Organism Vibrio tasmaniensis strain LMG 20012

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OCV44_RS15595 Protein ID WP_139684391.1
Coordinates 276173..276703 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OCV44_RS15600 Protein ID WP_139684390.1
Coordinates 276700..276969 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV44_RS15580 271457..272992 + 1536 WP_139684435.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
OCV44_RS15585 273009..274484 + 1476 WP_139684393.1 phosphomannomutase CpsG -
OCV44_RS15590 274599..275651 - 1053 WP_139684392.1 3-deoxy-7-phosphoheptulonate synthase AroG -
OCV44_RS15595 276173..276703 - 531 WP_139684391.1 GNAT family N-acetyltransferase Toxin
OCV44_RS15600 276700..276969 - 270 WP_139684390.1 DUF1778 domain-containing protein Antitoxin
OCV44_RS15605 277118..277420 + 303 Protein_236 transposase -
OCV44_RS15610 277580..277894 - 315 WP_139684389.1 DNA-binding transcriptional regulator -
OCV44_RS15615 277881..278213 - 333 WP_139684434.1 type II toxin-antitoxin system RelE/ParE family toxin -
OCV44_RS15620 278674..279480 - 807 WP_139684388.1 hypothetical protein -
OCV44_RS15625 280004..280222 - 219 WP_009845653.1 DUF3820 family protein -
OCV44_RS15630 280235..280906 - 672 WP_139684387.1 DUF3313 domain-containing protein -
OCV44_RS15635 281003..281356 - 354 WP_065099595.1 L-threonine 3-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19929.19 Da        Isoelectric Point: 8.7662

>T40343 WP_139684391.1 NZ_AP025511:c276703-276173 [Vibrio tasmaniensis]
VSYSKTFKELDKSQHDRESFDCGEKELNDFIQTQAAKHMQAGISRTMVLPASVPLPNQKYPICSFYSIAPSSISRDTLPQ
AMAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIKALEYLWEINSHMRAYAIVVDCLTEQAESFYAKYGFEVLCEING
RVRMFIPMKTVGKLFT

Download         Length: 531 bp

>T40343 NZ_AP025511:c276703-276173 [Vibrio tasmaniensis]
GTGAGTTATTCTAAAACTTTCAAAGAATTGGATAAATCACAACACGATAGAGAATCATTTGACTGCGGTGAAAAAGAGTT
AAATGACTTTATCCAAACTCAAGCCGCTAAACATATGCAAGCAGGTATCAGCCGCACTATGGTTTTGCCTGCTTCTGTGC
CACTGCCAAATCAAAAATATCCAATTTGTTCATTTTATAGTATTGCGCCAAGTTCAATTAGCCGTGATACGTTGCCACAA
GCGATGGCTAAAAAATTACCACGCTATCCAATTCCTGTTTTCCTTTTAGCTCAACTAGCAGTTCATAAAGAATTTCATGG
AAGTGGGTTAGGTAAAGTTAGCTTAATCAAAGCTCTCGAATATCTTTGGGAAATTAACTCTCACATGAGAGCTTATGCCA
TTGTTGTCGATTGTTTAACTGAACAAGCTGAGTCATTCTACGCAAAATATGGTTTCGAGGTTCTTTGTGAAATCAATGGT
CGTGTAAGAATGTTCATTCCGATGAAAACAGTCGGTAAATTATTCACTTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9777.17 Da        Isoelectric Point: 4.4290

>AT40343 WP_139684390.1 NZ_AP025511:c276969-276700 [Vibrio tasmaniensis]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVISEHEGITVEANVFDQFMIACDEAKAPNKALLEAA
AFTKSGEFK

Download         Length: 270 bp

>AT40343 NZ_AP025511:c276969-276700 [Vibrio tasmaniensis]
ATGGCTACTGCAAGACTTGATATTCGCTTGGATGAAGAAATCAAAGCTAAGGCTGAGAAAGCTTCAGCTTTACTTGGTTT
AAAAAGCTTAACTGAATACGTTGTTCGTCTAATGGACGAAGATTCAACTCAGGTAATTTCTGAGCATGAAGGTATCACTG
TTGAAGCAAATGTATTTGATCAATTCATGATTGCTTGTGACGAGGCTAAGGCTCCGAATAAAGCATTACTTGAAGCTGCT
GCATTTACTAAAAGTGGTGAGTTTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References