Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 587668..588215 Replicon chromosome
Accession NZ_AP025509
Organism Vibrio splendidus strain LMG 19031

Toxin (Protein)


Gene name relE Uniprot ID A0A1B9Q0U4
Locus tag OCU90_RS19905 Protein ID WP_017106966.1
Coordinates 587668..587970 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A855IM10
Locus tag OCU90_RS19910 Protein ID WP_061022887.1
Coordinates 587958..588215 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU90_RS19870 582771..583112 + 342 WP_055319869.1 hypothetical protein -
OCU90_RS19875 583112..584479 + 1368 WP_061022897.1 zonular occludens toxin domain-containing protein -
OCU90_RS19880 584625..584870 + 246 WP_061023085.1 hypothetical protein -
OCU90_RS19885 585304..585645 + 342 WP_061022895.1 hypothetical protein -
OCU90_RS19890 585645..586004 + 360 WP_061022893.1 hypothetical protein -
OCU90_RS19895 586206..586574 - 369 WP_061022891.1 phage protein -
OCU90_RS19900 587357..587614 - 258 WP_061022889.1 hypothetical protein -
OCU90_RS19905 587668..587970 - 303 WP_017106966.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU90_RS19910 587958..588215 - 258 WP_061022887.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU90_RS19915 588330..589040 - 711 WP_061022886.1 hypothetical protein -
OCU90_RS19920 589135..590070 - 936 Protein_494 DUF2806 domain-containing protein -
OCU90_RS19925 590179..590652 - 474 WP_061022881.1 hypothetical protein -
OCU90_RS19930 591020..591184 - 165 WP_155647277.1 hypothetical protein -
OCU90_RS19935 591181..591378 - 198 WP_061022880.1 hypothetical protein -
OCU90_RS19940 591770..593077 + 1308 WP_061022877.1 GGDEF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11682.49 Da        Isoelectric Point: 5.1862

>T40341 WP_017106966.1 NZ_AP025509:c587970-587668 [Vibrio splendidus]
MAEVIWSEPALSDLNDIAEYIALENLVAAKQLVRNIFDKVERLSDFPESGRLPPGLEHLNYREVVVNPCRVFYKQDGDKV
YILFVMRAERDLRRFLLSKQ

Download         Length: 303 bp

>T40341 NZ_AP025509:c587970-587668 [Vibrio splendidus]
ATGGCTGAAGTGATTTGGAGTGAGCCCGCGTTATCGGACCTTAACGATATCGCGGAATACATAGCCCTTGAAAACTTAGT
CGCGGCCAAACAGCTGGTTCGAAACATTTTCGACAAAGTTGAACGTCTCAGCGACTTTCCCGAGTCTGGGCGTCTGCCTC
CAGGGCTCGAGCACTTAAATTATCGCGAAGTCGTAGTGAATCCATGTCGAGTTTTCTACAAGCAAGACGGTGACAAAGTG
TACATCTTGTTTGTGATGCGCGCGGAGCGAGATTTACGTCGATTTTTGCTGAGCAAACAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9637.11 Da        Isoelectric Point: 7.3177

>AT40341 WP_061022887.1 NZ_AP025509:c588215-587958 [Vibrio splendidus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYQFMQNRLAILEGIARGERAISEGKSLSHDEAKDKM
SKWLK

Download         Length: 258 bp

>AT40341 NZ_AP025509:c588215-587958 [Vibrio splendidus]
ATGAAAGTCGAGCTCGTTACTTCCCTTAAGCGTCAAGCGACCAAAATCCTTGCCGACCTACACGACACCAAAGAGCCCGT
GTTGATCACCGAGCATGGCAAACCTTCAGCGTATCTCGTGGATGTTGACGACTATCAGTTTATGCAAAACCGCTTGGCTA
TCCTCGAAGGGATCGCACGCGGTGAGCGCGCCATTTCTGAAGGCAAGTCGCTGAGCCATGACGAAGCCAAAGACAAGATG
TCAAAATGGCTGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B9Q0U4

Antitoxin

Source ID Structure
AlphaFold DB A0A855IM10

References