Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 471138..471697 Replicon chromosome
Accession NZ_AP025507
Organism Vibrio pomeroyi strain LMG 20537

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCV12_RS18280 Protein ID WP_102445494.1
Coordinates 471138..471416 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCV12_RS18285 Protein ID WP_261886810.1
Coordinates 471413..471697 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV12_RS18255 466441..467946 - 1506 WP_261886806.1 SgrR family transcriptional regulator -
OCV12_RS18260 467956..468966 - 1011 WP_261886807.1 Gfo/Idh/MocA family oxidoreductase -
OCV12_RS18265 469084..469983 - 900 WP_261886808.1 homocysteine S-methyltransferase family protein -
OCV12_RS18270 470120..470317 - 198 Protein_410 IS110 family transposase -
OCV12_RS18275 470416..471099 + 684 WP_261886809.1 hypothetical protein -
OCV12_RS18280 471138..471416 - 279 WP_102445494.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCV12_RS18285 471413..471697 - 285 WP_261886810.1 DUF1778 domain-containing protein Antitoxin
OCV12_RS18290 471882..472583 + 702 WP_261886811.1 lipoate--protein ligase -
OCV12_RS18295 472827..473702 - 876 WP_261886812.1 radical SAM protein -
OCV12_RS18300 473922..474758 - 837 WP_261886813.1 SDR family NAD(P)-dependent oxidoreductase -
OCV12_RS18305 474931..475776 - 846 WP_261886814.1 enoyl-CoA hydratase/isomerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 470117..470317 200


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10949.63 Da        Isoelectric Point: 4.2290

>T40338 WP_102445494.1 NZ_AP025507:c471416-471138 [Vibrio pomeroyi]
MILWEEESLNDRERIFEFIYDFNPDAAENADNLIETKVENLLDQPLMGVQRDGIRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPMD

Download         Length: 279 bp

>T40338 NZ_AP025507:c471416-471138 [Vibrio pomeroyi]
ATGATTTTATGGGAAGAAGAATCACTCAATGATCGTGAAAGGATCTTTGAGTTTATCTATGACTTCAACCCTGATGCGGC
AGAGAACGCAGACAACCTCATTGAAACAAAAGTAGAAAACTTGCTTGATCAGCCTCTGATGGGTGTACAGAGAGACGGTA
TTCGTGGACGATTACTGATAATTCCTGAGATTTCGATGATCGTCTCCTATTGGATCGAAGGCGACATTATCCGAATTATG
CGCGTGCTCCACCAGAAACAAAAGTTCCCTATGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11011.32 Da        Isoelectric Point: 9.2520

>AT40338 WP_261886810.1 NZ_AP025507:c471697-471413 [Vibrio pomeroyi]
MDTRIQFRVDEETKRLAQQMAESQGRTLSGACRELTEQLAEQQRQTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT40338 NZ_AP025507:c471697-471413 [Vibrio pomeroyi]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAGATGGCTGAGAGCCAAGGTCGTAC
ACTGAGTGGTGCTTGCCGTGAGCTTACTGAGCAACTCGCAGAGCAGCAAAGACAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAACACCAAACGGCTAAATCTCGA
ATGGAAGAACGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References