Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 253325..253833 Replicon plasmid pATCC25916
Accession NZ_AP025505
Organism Vibrio pelagius strain ATCC 25916

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag vsple_RS21295 Protein ID WP_261884088.1
Coordinates 253325..253585 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag vsple_RS21300 Protein ID WP_261884089.1
Coordinates 253582..253833 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
vsple_RS21275 249631..250956 - 1326 WP_261884084.1 IS4 family transposase -
vsple_RS21280 251024..251293 - 270 WP_261884085.1 IS66 family insertion sequence element accessory protein TnpB -
vsple_RS21285 251290..251601 - 312 WP_261884086.1 IS66 family insertion sequence element accessory protein TnpB -
vsple_RS21290 252007..253128 + 1122 WP_261884087.1 ISAs1 family transposase -
vsple_RS21295 253325..253585 - 261 WP_261884088.1 Txe/YoeB family addiction module toxin Toxin
vsple_RS21300 253582..253833 - 252 WP_261884089.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
vsple_RS21305 254173..254538 - 366 WP_261884090.1 hypothetical protein -
vsple_RS21310 254887..255867 + 981 WP_261884091.1 helix-turn-helix domain-containing protein -
vsple_RS21315 256024..257241 + 1218 WP_261884092.1 serine hydrolase domain-containing protein -
vsple_RS21320 257357..258100 + 744 WP_261884093.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..395604 395604


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10483.99 Da        Isoelectric Point: 9.7860

>T40337 WP_261884088.1 NZ_AP025505:c253585-253325 [Vibrio pelagius]
MKLTFSTNAWEDYLYWQKTDKKILKRINTLIKDIQREPYDGIGKPEPLKHGLSGYWSRRINDEHRIVYRYHDETILIAQL
RFHYGT

Download         Length: 261 bp

>T40337 NZ_AP025505:c253585-253325 [Vibrio pelagius]
ATGAAATTGACCTTCTCAACTAATGCTTGGGAAGACTATTTGTATTGGCAAAAAACTGACAAAAAAATTCTCAAGCGCAT
CAACACCCTTATAAAAGATATACAGCGTGAGCCATATGACGGCATAGGTAAACCTGAACCACTCAAACATGGATTATCTG
GATATTGGTCCCGTCGTATAAATGATGAACACCGTATTGTTTATCGCTATCACGATGAAACGATTTTGATTGCTCAGTTG
AGATTTCACTACGGCACATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9254.55 Da        Isoelectric Point: 4.5959

>AT40337 WP_261884089.1 NZ_AP025505:c253833-253582 [Vibrio pelagius]
MDAISYTAARANLATTMQKVCNDHAPVIITRKSEAPVVMISLEDYEAMQETTYLLRAPTNARRLLESVAELESGKGQERE
LLE

Download         Length: 252 bp

>AT40337 NZ_AP025505:c253833-253582 [Vibrio pelagius]
ATGGACGCTATTAGTTACACTGCCGCTAGAGCAAACCTCGCAACTACAATGCAAAAAGTCTGCAATGACCATGCTCCGGT
AATCATTACACGTAAGAGCGAAGCACCTGTTGTGATGATATCACTCGAGGACTATGAAGCAATGCAAGAAACCACATATC
TTTTGCGTGCCCCGACTAATGCTCGTCGGTTGCTTGAGTCTGTCGCGGAATTAGAATCAGGTAAGGGACAAGAGAGAGAG
TTGCTGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References