Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 30137..30653 Replicon plasmid pATCC25916
Accession NZ_AP025505
Organism Vibrio pelagius strain ATCC 25916

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag vsple_RS20300 Protein ID WP_261884220.1
Coordinates 30384..30653 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag vsple_RS20295 Protein ID WP_255232963.1
Coordinates 30137..30391 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
vsple_RS20270 25205..26515 + 1311 WP_261884217.1 DUF1501 domain-containing protein -
vsple_RS20275 26662..27255 - 594 WP_261884218.1 NAD(P)H-dependent oxidoreductase -
vsple_RS20280 27252..28160 - 909 Protein_23 EamA family transporter -
vsple_RS20285 28291..28773 + 483 WP_150897498.1 MarR family transcriptional regulator -
vsple_RS20290 28974..29948 + 975 WP_261884219.1 DHH family phosphoesterase -
vsple_RS20295 30137..30391 + 255 WP_255232963.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
vsple_RS20300 30384..30653 + 270 WP_261884220.1 Txe/YoeB family addiction module toxin Toxin
vsple_RS20305 30804..32183 - 1380 WP_261884221.1 nucleobase:cation symporter-2 family protein -
vsple_RS20310 32827..33411 + 585 WP_261884222.1 NAD(P)H-dependent oxidoreductase -
vsple_RS20315 33422..33988 + 567 WP_261884223.1 carboxymuconolactone decarboxylase family protein -
vsple_RS20320 34205..35113 - 909 WP_261884224.1 EamA family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..395604 395604


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10601.92 Da        Isoelectric Point: 8.8578

>T40336 WP_261884220.1 NZ_AP025505:30384-30653 [Vibrio pelagius]
MSSSQRLLSWTDEAWNDYLYWQTQDKKTLKRVNKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDETNRLVYAVDDQAT
TVISCRYHY

Download         Length: 270 bp

>T40336 NZ_AP025505:30384-30653 [Vibrio pelagius]
ATGAGTAGTAGTCAGCGCCTGCTCTCATGGACTGATGAGGCGTGGAACGACTATTTATACTGGCAAACTCAAGATAAGAA
AACACTAAAACGAGTCAACAAACTCATCAATGATGTCAAGCGGTCACCTTTTGAAGGTATTGGAAAGCCAGAACCGTTAA
AAGAGAATCTTTCGGGGTTTTGGTCTAGGCGAATTGATGAAACTAATCGATTGGTGTATGCCGTAGATGATCAAGCGACC
ACAGTCATTTCATGTCGCTACCATTACTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9655.77 Da        Isoelectric Point: 4.8500

>AT40336 WP_255232963.1 NZ_AP025505:30137-30391 [Vibrio pelagius]
MRIVSFTEARNSLKSVLDGVVDDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLSRSIEQYRHGKTTERE
LIDE

Download         Length: 255 bp

>AT40336 NZ_AP025505:30137-30391 [Vibrio pelagius]
ATGCGAATCGTATCTTTTACTGAAGCAAGGAACAGTCTTAAATCTGTACTAGATGGGGTGGTGGACGATGCTGATACCAC
GGTGATCACTCGTCGCGATTCCGAAGATGCTGTCGTTATGTCTTTAGACTATTACAACAGTTTGATGGAAACGGTGCACT
TGCTGCGCTCACCCAAGAATGCGGAGCATTTGAGTCGTTCTATTGAGCAATACCGTCATGGTAAGACAACGGAGCGAGAA
TTAATCGATGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References