40327

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 40365..41707 Replicon plasmid p1
Accession NZ_AP025501
Organism Vibrio lentus strain LMG 21034

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag OCV49_RS25410 Protein ID WP_192854504.1
Coordinates 40772..41707 (+) Length 312 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag OCV49_RS25405 Protein ID WP_192854500.1
Coordinates 40365..40769 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV49_RS25395 36375..39188 + 2814 WP_192854497.1 conjugal transfer mating-pair stabilization protein TraG -
OCV49_RS25400 39272..39808 + 537 WP_192854498.1 hypothetical protein -
OCV49_RS25405 40365..40769 + 405 WP_192854500.1 DUF6088 family protein Antitoxin
OCV49_RS25410 40772..41707 + 936 WP_192854504.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
OCV49_RS25415 42153..42296 + 144 WP_192854745.1 hypothetical protein -
OCV49_RS25420 42529..44001 + 1473 WP_192854744.1 group II intron reverse transcriptase/maturase -
OCV49_RS25425 44412..44615 - 204 WP_192854678.1 hypothetical protein -
OCV49_RS25430 44855..45292 + 438 WP_192854770.1 IS200/IS605 family transposase -
OCV49_RS25435 45741..46211 - 471 WP_192854756.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..251461 251461
- flank IS/Tn - - 44855..45292 437


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 312 a.a.        Molecular weight: 35971.16 Da        Isoelectric Point: 5.6457

>T40327 WP_192854504.1 NZ_AP025501:40772-41707 [Vibrio lentus]
IPKLKKQFLEVSDALDLGNPSITEKDYWVVSLLAMLENVKSEHHRLVFSGGTALAKSNIKILRMSEDVDIKLIPTQEFLD
KGTGAKKRARKALVEHLIARLVEHPYLNYSDKTVRDEYRYVEIEIEYPQQYHQAPCLRPYIKLEFIETIELQGVESRSIS
SLVAQSYKQPAEVSAMSCISIDSTLVEKVLSMLRRTMSVKRDPKRKDDETLVRHIYDVHCISVEHTIDMDVLKPMFDTVL
EEDKERYGNQHQEFIDDPRNELKLGLEELETNEEFRKRFGAFVAPMVYNSEPHNFDTCFASFKGISEQLIA

Download         Length: 936 bp

>T40327 NZ_AP025501:40772-41707 [Vibrio lentus]
ATACCAAAACTAAAAAAGCAGTTTCTTGAAGTCTCTGATGCCCTCGACTTAGGTAACCCATCGATCACGGAAAAGGACTA
TTGGGTGGTGTCACTGCTTGCCATGTTGGAAAACGTGAAAAGTGAGCACCACAGGCTCGTTTTTTCAGGTGGAACAGCTT
TGGCCAAGTCCAACATTAAGATCCTGCGTATGTCTGAAGACGTCGACATAAAATTGATTCCAACTCAGGAATTTCTCGAC
AAGGGCACAGGTGCGAAGAAAAGAGCTCGTAAGGCGTTAGTCGAACACCTCATAGCGAGGTTAGTTGAGCACCCTTATCT
GAATTACAGTGATAAAACGGTACGCGATGAGTATCGCTATGTCGAAATCGAAATAGAGTACCCGCAACAATACCATCAAG
CACCGTGTCTACGACCTTATATCAAACTTGAGTTCATCGAGACCATTGAACTTCAAGGCGTTGAATCTCGCTCTATTTCA
TCGCTGGTAGCACAGAGCTACAAGCAACCTGCCGAAGTAAGCGCTATGTCGTGTATTTCCATTGATTCGACGTTGGTTGA
AAAAGTGCTTTCCATGTTACGCCGCACCATGTCAGTCAAGCGTGATCCAAAGCGTAAGGATGACGAAACATTGGTTCGTC
ACATCTACGATGTTCATTGCATTAGCGTAGAGCATACGATTGATATGGACGTGTTAAAGCCGATGTTTGATACCGTGTTG
GAAGAAGACAAGGAGCGATATGGAAATCAACATCAGGAGTTTATCGACGATCCACGTAATGAGTTAAAGCTGGGATTAGA
AGAGCTAGAAACCAACGAGGAGTTTCGTAAACGTTTTGGGGCGTTTGTGGCTCCAATGGTGTACAACTCAGAGCCACATA
ACTTTGATACCTGTTTTGCTTCGTTTAAAGGGATTTCAGAGCAGCTTATCGCCTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15511.98 Da        Isoelectric Point: 10.7446

>AT40327 WP_192854500.1 NZ_AP025501:40365-40769 [Vibrio lentus]
MTATDRIYQKIKRSRRYVFERKDFDNYASYDQIGRVLKKLVDKGVLMKIGYGLYTKSTINSLTNKPMPMNPGGPDAIMRE
ILKLRGVDFEMDAMSLKSINGQSTQIPASIRYTWDSKHFNRSLKVGNRVLNNRQ

Download         Length: 405 bp

>AT40327 NZ_AP025501:40365-40769 [Vibrio lentus]
ATGACAGCAACTGACCGTATTTATCAAAAGATAAAACGCTCTCGCCGCTATGTGTTCGAACGTAAAGATTTCGACAACTA
TGCGAGCTATGACCAAATTGGTCGTGTCTTGAAAAAACTGGTGGATAAAGGTGTACTGATGAAAATAGGGTATGGCTTAT
ACACCAAGTCAACGATCAACAGCCTAACTAATAAACCAATGCCAATGAACCCCGGTGGTCCTGACGCAATCATGCGTGAG
ATCCTAAAATTGCGCGGTGTAGACTTTGAGATGGATGCCATGTCATTGAAGAGCATCAATGGACAGTCCACTCAAATACC
AGCGTCCATCAGATACACGTGGGATTCTAAGCATTTCAACCGCAGCCTTAAGGTTGGTAACAGAGTATTGAATAATCGAC
AATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References