Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2526315..2526859 Replicon chromosome
Accession NZ_AP025499
Organism Vibrio lentus strain LMG 21034

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OCV49_RS11715 Protein ID WP_192854322.1
Coordinates 2526554..2526859 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OCV49_RS11710 Protein ID WP_171342103.1
Coordinates 2526315..2526557 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV49_RS11685 2521749..2522114 + 366 WP_192854317.1 hypothetical protein -
OCV49_RS11690 2522230..2523414 + 1185 WP_192854318.1 FIST N-terminal domain-containing protein -
OCV49_RS11695 2523414..2525141 + 1728 WP_192854319.1 ATP-binding protein -
OCV49_RS11700 2525588..2526010 + 423 WP_192854320.1 phage protein -
OCV49_RS11705 2526025..2526201 + 177 WP_192854321.1 hypothetical protein -
OCV49_RS11710 2526315..2526557 + 243 WP_171342103.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
OCV49_RS11715 2526554..2526859 + 306 WP_192854322.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCV49_RS11720 2526943..2527902 - 960 WP_192854323.1 hypothetical protein -
OCV49_RS11725 2528056..2529096 - 1041 WP_192854324.1 AAA family ATPase -
OCV49_RS11730 2529093..2529461 - 369 WP_192854325.1 hypothetical protein -
OCV49_RS11735 2529654..2530145 - 492 WP_261890930.1 toll/interleukin-1 receptor domain-containing protein -
OCV49_RS11740 2530743..2531006 - 264 WP_192854327.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2526315..2551193 24878


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11880.77 Da        Isoelectric Point: 10.7649

>T40325 WP_192854322.1 NZ_AP025499:2526554-2526859 [Vibrio lentus]
MTPFQLTNKAKADLRDIALFTERRWGRKQRNVYIRQFDTTFGRLAENPELGKTCDEIRPGYRKFPQASHVIFYQKTNNQP
LLIIRILHKSMDVLPIFGAQT

Download         Length: 306 bp

>T40325 NZ_AP025499:2526554-2526859 [Vibrio lentus]
ATGACGCCTTTTCAGCTCACGAACAAGGCAAAGGCCGATCTTAGAGACATTGCCTTGTTTACTGAGCGTCGTTGGGGTCG
CAAGCAACGAAATGTCTATATCAGACAGTTCGATACCACATTTGGCCGCTTAGCGGAGAATCCGGAGCTTGGAAAAACCT
GTGATGAAATCAGGCCAGGTTACCGAAAATTCCCACAGGCCAGTCATGTCATTTTCTACCAGAAAACGAACAACCAACCT
CTCCTAATCATACGAATCTTACACAAAAGTATGGATGTACTTCCCATCTTTGGCGCACAAACTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8981.93 Da        Isoelectric Point: 4.3085

>AT40325 WP_171342103.1 NZ_AP025499:2526315-2526557 [Vibrio lentus]
MARNTSITLGEHFDGFIASQIQSGRYGSASEVIRSALRLLETQETKMNTLRQLLVEGENSGIADYDLDTFINELDSEERK

Download         Length: 243 bp

>AT40325 NZ_AP025499:2526315-2526557 [Vibrio lentus]
ATGGCGAGAAATACAAGCATTACCTTGGGTGAACACTTTGATGGGTTTATTGCGAGCCAGATCCAAAGCGGTCGTTATGG
CTCAGCCAGCGAGGTGATCCGATCGGCGCTGCGTTTACTCGAAACCCAAGAGACGAAAATGAATACGTTACGACAGCTGC
TCGTGGAAGGTGAAAACAGTGGGATCGCGGATTACGACCTCGATACTTTCATTAATGAACTCGACAGTGAAGAAAGAAAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References