Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) sdenTA/AbiEii(toxin)
Location 3317131..3318560 Replicon chromosome
Accession NZ_AP025483
Organism Vibrio echinoideorum strain DSM 107264

Toxin (Protein)


Gene name sdenT Uniprot ID -
Locus tag OCV36_RS15040 Protein ID WP_135455639.1
Coordinates 3317670..3318560 (+) Length 297 a.a.

Antitoxin (Protein)


Gene name sdenA Uniprot ID -
Locus tag OCV36_RS15035 Protein ID WP_135455637.1
Coordinates 3317131..3317655 (+) Length 175 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV36_RS15010 3313151..3314215 + 1065 WP_135455633.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
OCV36_RS15015 3314474..3315553 - 1080 WP_135455635.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
OCV36_RS15020 3315894..3316172 + 279 WP_050652034.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
OCV36_RS15025 3316222..3316432 + 211 Protein_2850 type II toxin-antitoxin system YafQ family toxin -
OCV36_RS15030 3316519..3316944 - 426 Protein_2851 Rpn family recombination-promoting nuclease/putative transposase -
OCV36_RS15035 3317131..3317655 + 525 WP_135455637.1 hypothetical protein Antitoxin
OCV36_RS15040 3317670..3318560 + 891 WP_135455639.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
OCV36_RS15045 3318856..3320265 - 1410 WP_135455641.1 sulfate adenylyltransferase subunit CysN -
OCV36_RS15050 3320410..3321372 - 963 WP_135455643.1 DHH family phosphoesterase -
OCV36_RS15055 3321372..3322019 - 648 WP_135455644.1 adenylyl-sulfate kinase -
OCV36_RS15060 3322026..3322934 - 909 WP_210114716.1 sulfate adenylyltransferase subunit CysD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - wbtL 3317131..3346644 29513


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(42-265)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 297 a.a.        Molecular weight: 34245.15 Da        Isoelectric Point: 6.6127

>T40323 WP_135455639.1 NZ_AP025483:3317670-3318560 [Vibrio echinoideorum]
MLKQKIDEILKRNPELAPVVEVIEKEILHHDILHVMTEHGALQRLTFIGGTSLRLCYNSSRLSEDLDFNGGHDFKPSMFD
GLEDKIQSFLQKKYEIPVYVNKPSPDKQGNTSSWKISIEKEPNRADLPRQKMHIDVCALPSFDLTNRVPINHYGIDTPTE
GMLIRCQTMDEILADKFIALAYRARRIKPRDVWDIVWLNQRGIEVNNQLINNKLEARDKERDDFLIALGRQMKNLTENDA
VKADFNSEMSRFVPQTLQAKTLDVPEYWDYVRETISNMGKRVSQPSSPTNKFDMSL

Download         Length: 891 bp

>T40323 NZ_AP025483:3317670-3318560 [Vibrio echinoideorum]
ATGCTAAAACAAAAAATAGACGAAATTCTAAAACGTAACCCTGAGTTAGCACCCGTTGTTGAAGTGATCGAAAAAGAGAT
ACTTCATCATGATATTTTGCATGTCATGACAGAACACGGGGCACTACAAAGACTCACCTTCATTGGCGGTACCTCACTAC
GCCTTTGCTACAACAGTTCTCGGTTATCTGAAGACTTAGACTTTAATGGTGGTCATGATTTTAAGCCATCGATGTTTGAT
GGGCTTGAGGATAAAATACAGAGCTTTTTGCAAAAGAAATATGAAATACCTGTATACGTCAATAAACCTAGCCCAGACAA
GCAAGGGAATACATCATCGTGGAAAATCAGCATCGAGAAAGAACCAAACCGTGCTGATCTGCCCAGACAGAAAATGCACA
TTGATGTTTGTGCTTTACCCTCTTTCGATTTGACAAATCGAGTGCCTATAAATCACTACGGAATTGACACACCAACAGAA
GGTATGCTGATCCGTTGCCAAACAATGGACGAGATTTTAGCTGATAAATTCATTGCTTTAGCATACAGGGCAAGGCGAAT
TAAGCCCCGTGATGTGTGGGATATTGTGTGGCTAAATCAAAGAGGCATTGAGGTCAATAACCAGTTAATCAACAACAAAC
TAGAGGCCCGTGACAAAGAACGTGATGACTTTTTGATTGCGCTGGGCAGGCAAATGAAAAACCTAACTGAAAATGATGCA
GTTAAGGCTGACTTCAACAGCGAGATGAGTCGATTTGTACCTCAAACATTGCAAGCAAAAACGCTTGATGTACCTGAGTA
TTGGGACTATGTGAGAGAAACAATCAGTAACATGGGTAAGAGAGTTTCACAACCAAGCTCACCAACAAATAAATTTGATA
TGAGCCTTTAG

Antitoxin


Download         Length: 175 a.a.        Molecular weight: 19986.17 Da        Isoelectric Point: 10.2066

>AT40323 WP_135455637.1 NZ_AP025483:3317131-3317655 [Vibrio echinoideorum]
VTKVEKLISAMAESSKFGKGVFSKAELAYLLNVEQTPRFNKFLYDCVKKGTINRIANGLFESTITPPNPRTAIYEVARKL
RPGYLNYISLESELSRTGEISQIIMDRLTLMTRGRSGTFKTRYGVVEFTHTKHKVSQLENDLFFDEEVKMYRAMPHRALA
DLKSCKRNLQMINH

Download         Length: 525 bp

>AT40323 NZ_AP025483:3317131-3317655 [Vibrio echinoideorum]
GTGACTAAGGTAGAAAAACTAATTTCAGCTATGGCTGAATCAAGTAAATTTGGCAAAGGCGTATTCAGTAAGGCTGAACT
TGCCTACCTTCTCAATGTCGAACAAACACCCCGTTTTAACAAATTTCTGTACGACTGTGTTAAAAAAGGCACCATTAATC
GAATCGCTAATGGTCTTTTTGAAAGCACAATCACCCCTCCAAATCCCCGAACTGCAATATATGAAGTCGCCCGTAAATTA
AGGCCTGGCTACCTAAATTATATAAGTTTAGAGAGTGAATTATCACGTACTGGAGAGATATCTCAAATCATTATGGATCG
CCTGACTCTAATGACTCGGGGGCGAAGTGGGACATTTAAAACTCGCTACGGAGTGGTTGAGTTTACACATACTAAGCACA
AAGTATCACAGCTTGAAAATGACCTATTCTTCGACGAAGAGGTGAAAATGTATCGAGCTATGCCTCATCGAGCATTAGCC
GATTTAAAAAGCTGTAAACGAAACCTACAAATGATAAATCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References