Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 3309914..3310473 Replicon chromosome
Accession NZ_AP025483
Organism Vibrio echinoideorum strain DSM 107264

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCV36_RS14995 Protein ID WP_135455628.1
Coordinates 3309914..3310192 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCV36_RS15000 Protein ID WP_167853018.1
Coordinates 3310189..3310473 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCV36_RS14965 3305276..3305764 + 489 WP_135455618.1 helix-turn-helix transcriptional regulator -
OCV36_RS14970 3306186..3307349 + 1164 WP_135455620.1 DUF3596 domain-containing protein -
OCV36_RS14975 3307346..3308056 + 711 WP_245300914.1 hypothetical protein -
OCV36_RS14980 3308160..3308405 + 246 WP_135455622.1 type II toxin-antitoxin system CcdA family antitoxin -
OCV36_RS14985 3308405..3308722 + 318 WP_135455624.1 CcdB family protein -
OCV36_RS14990 3309072..3309626 - 555 WP_135455626.1 GTP pyrophosphokinase -
OCV36_RS14995 3309914..3310192 - 279 WP_135455628.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCV36_RS15000 3310189..3310473 - 285 WP_167853018.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OCV36_RS15005 3311265..3312797 - 1533 WP_135455632.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase -
OCV36_RS15010 3313151..3314215 + 1065 WP_135455633.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10867.51 Da        Isoelectric Point: 4.4508

>T40322 WP_135455628.1 NZ_AP025483:c3310192-3309914 [Vibrio echinoideorum]
MILWEEESLNDREKIFEFLYDFNPEVAERTDNIIEAKVENLLEQPLMGAQREGARGRLLIISEVSMIVSYWVEGSIIRIM
RVLHQKQKFPTD

Download         Length: 279 bp

>T40322 NZ_AP025483:c3310192-3309914 [Vibrio echinoideorum]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGAGAGAAGATCTTTGAATTCCTCTACGACTTTAATCCAGAGGTAGC
TGAAAGAACCGATAATATTATTGAAGCCAAAGTCGAAAACTTGCTTGAGCAACCTTTAATGGGAGCGCAACGTGAAGGCG
CTCGAGGCAGACTACTCATTATTTCTGAAGTTTCGATGATTGTTTCATATTGGGTTGAAGGTTCAATTATCCGTATTATG
CGAGTTCTACATCAGAAGCAAAAATTCCCTACAGACTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10913.21 Da        Isoelectric Point: 9.0980

>AT40322 WP_167853018.1 NZ_AP025483:c3310473-3310189 [Vibrio echinoideorum]
MDARIQFRVDDETKRLAQQLAESQGRTLSDACRELTEQMAEHQRKTLSHDAWLTEQVKLAFEKYDSGKAVFIDNDSAKSR
MEARKARIRSRGQQ

Download         Length: 285 bp

>AT40322 NZ_AP025483:c3310473-3310189 [Vibrio echinoideorum]
ATGGATGCTAGAATCCAATTTCGTGTTGATGACGAAACAAAACGCCTAGCTCAGCAATTGGCTGAGAGCCAAGGTCGCAC
TCTTAGTGATGCTTGCCGTGAACTGACAGAACAAATGGCAGAGCATCAAAGAAAGACACTATCTCATGATGCTTGGTTAA
CAGAACAAGTAAAACTTGCTTTTGAAAAGTATGACTCTGGCAAAGCGGTGTTTATTGACAATGATTCAGCCAAATCTCGA
ATGGAAGCCCGTAAAGCGAGGATTCGTAGCCGAGGTCAACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References