Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 3126029..3126795 Replicon chromosome
Accession NZ_AP025480
Organism Vibrio cyclitrophicus strain LMG 21359

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag OCW38_RS13725 Protein ID WP_261894498.1
Coordinates 3126029..3126538 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag OCW38_RS13730 Protein ID WP_261894500.1
Coordinates 3126529..3126795 (-) Length 89 a.a.

Genomic Context

OCW38_RS13705OCW38_RS13710OCW38_RS13735OCW38_RS13745OCW38_RS13750OCW38_RS13755OCW38_RS13715OCW38_RS13720OCW38_RS13725OCW38_RS13730OCW38_RS13740OCW38_RS13760
Location: 3122607..3122654 (48 bp)
Type: Others
Protein ID: Protein_2593
Location: 3122908..3123420 (513 bp)
Type: Others
Protein ID: WP_261894493.1
Location: 3127009..3128151 (1143 bp)
Type: Others
Protein ID: WP_261894502.1
Location: 3128977..3129810 (834 bp)
Type: Others
Protein ID: WP_102397595.1
Location: 3129791..3129967 (177 bp)
Type: Others
Protein ID: Protein_2602
Location: 3130221..3130685 (465 bp)
Type: Others
Protein ID: WP_261894507.1
Location: 3123536..3124891 (1356 bp)
Type: Others
Protein ID: WP_065100529.1
Location: 3125575..3125841 (267 bp)
Type: Others
Protein ID: WP_261894496.1
Location: 3126029..3126538 (510 bp)
Type: Toxin
Protein ID: WP_261894498.1
Location: 3126529..3126795 (267 bp)
Type: Antitoxin
Protein ID: WP_261894500.1
Location: 3128556..3128864 (309 bp)
Type: Others
Protein ID: WP_261894504.1
Location: 3130756..3131694 (939 bp)
Type: Others
Protein ID: WP_261894509.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OCW38_RS137053122607..3122654+48Protein_2593DNA-binding protein-
OCW38_RS137103122908..3123420+513WP_261894493.1DUF2442 domain-containing protein-
OCW38_RS137153123536..3124891-1356WP_065100529.1Fic family protein-
OCW38_RS137203125575..3125841-267WP_261894496.1hypothetical protein-
OCW38_RS137253126029..3126538-510WP_261894498.1GNAT family N-acetyltransferaseToxin
OCW38_RS137303126529..3126795-267WP_261894500.1DUF1778 domain-containing proteinAntitoxin
OCW38_RS137353127009..3128151+1143WP_261894502.1transposase-
OCW38_RS137403128556..3128864-309WP_261894504.1hypothetical protein-
OCW38_RS137453128977..3129810+834WP_102397595.1hypothetical protein-
OCW38_RS137503129791..3129967+177Protein_2602IS1634 family transposase-
OCW38_RS137553130221..3130685+465WP_261894507.1hypothetical protein-
OCW38_RS137603130756..3131694-939WP_261894509.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--3127009..31281511142


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 18367.34 Da        Isoelectric Point: 8.4684

>T40318 WP_261894498.1 NZ_AP025480:c3126538-3126029 [Vibrio cyclitrophicus]
MGLVKPRLLIGSDLTSSFHCGVESLDLWLKKQALKSQNRGNTKTYVVTDSDTNAVVGYYAIAMGSVSRDIAFSALKRNSP
DPIPMVVLARLAVDLKYQGKHVAIGLLKDCILRSMAAMEVVGGAGILIHALDDNAQSFYKRFGFKESSIDSLVLMARISD
LTESLTLET

Download         Length: 510 bp

>T40318 NZ_AP025480:c3126538-3126029 [Vibrio cyclitrophicus]
TTGGGATTAGTTAAACCTCGTTTATTAATAGGTAGTGATCTCACGAGTTCTTTTCACTGTGGTGTTGAGTCCTTAGATCT
GTGGCTTAAGAAACAAGCGCTAAAAAGTCAAAACCGTGGTAATACGAAAACTTATGTCGTCACTGATTCAGATACGAATG
CTGTAGTGGGATACTACGCTATCGCGATGGGGTCAGTATCAAGAGATATTGCTTTTAGTGCTTTAAAACGAAATAGCCCA
GACCCAATACCAATGGTGGTATTAGCAAGGCTGGCCGTTGATTTGAAATATCAGGGCAAACACGTTGCGATTGGTTTGCT
TAAAGACTGTATTTTGCGCTCCATGGCAGCAATGGAAGTGGTCGGTGGAGCAGGTATATTAATTCATGCTTTGGACGATA
ATGCACAGTCCTTCTATAAACGGTTTGGCTTTAAAGAATCGAGCATCGATAGTTTGGTGTTGATGGCGAGAATCAGTGAT
TTAACAGAATCACTTACGCTGGAAACGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9945.34 Da        Isoelectric Point: 4.5917

>AT40318 WP_261894500.1 NZ_AP025480:c3126795-3126529 [Vibrio cyclitrophicus]
MATKSAPINMRVFPSVRDVIDAAANLQKVDRTVFIQQAALNEAQKVLADQKDFKLEQDAFDAFEQALDEPPKVLKGIQDL
FERKAPWD

Download         Length: 267 bp

>AT40318 NZ_AP025480:c3126795-3126529 [Vibrio cyclitrophicus]
ATGGCTACTAAATCAGCCCCGATCAATATGCGCGTATTCCCCTCCGTCCGTGATGTTATTGACGCAGCAGCAAACCTACA
GAAAGTGGATAGAACCGTATTTATTCAGCAAGCCGCTTTGAATGAAGCTCAAAAAGTACTGGCAGATCAGAAAGACTTCA
AATTAGAACAAGACGCATTTGACGCATTTGAACAAGCGCTTGATGAGCCACCTAAAGTTCTTAAAGGTATTCAAGATTTA
TTCGAAAGGAAGGCACCTTGGGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References