Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 124076..124638 Replicon plasmid p1
Accession NZ_AP025478
Organism Vibrio crassostreae strain LMG 22240

Toxin (Protein)


Gene name parE Uniprot ID A0A1B1C333
Locus tag OC193_RS24830 Protein ID WP_017061973.1
Coordinates 124076..124378 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A1B1C393
Locus tag OC193_RS24835 Protein ID WP_017061972.1
Coordinates 124378..124638 (-) Length 87 a.a.

Genomic Context

OC193_RS24815OC193_RS24820OC193_RS24825OC193_RS24840OC193_RS24845OC193_RS24850OC193_RS24855OC193_RS24870OC193_RS24875OC193_RS24810OC193_RS24830OC193_RS24835OC193_RS24860OC193_RS24865
Location: 121481..122506 (1026 bp)
Type: Others
Protein ID: WP_048660681.1
Location: 122503..123417 (915 bp)
Type: Others
Protein ID: WP_048660680.1
Location: 123599..124072 (474 bp)
Type: Others
Protein ID: WP_230690977.1
Location: 124854..125411 (558 bp)
Type: Others
Protein ID: WP_048659321.1
Location: 125583..125903 (321 bp)
Type: Others
Protein ID: WP_080967496.1
Location: 125993..126292 (300 bp)
Type: Others
Protein ID: WP_048659322.1
Location: 126461..127147 (687 bp)
Type: Others
Protein ID: WP_048659323.1
Location: 128374..128610 (237 bp)
Type: Others
Protein ID: WP_048659326.1
Location: 128621..128794 (174 bp)
Type: Others
Protein ID: WP_162200897.1
Location: 119650..119772 (123 bp)
Type: Others
Protein ID: WP_259739813.1
Location: 124076..124378 (303 bp)
Type: Toxin
Protein ID: WP_017061973.1
Location: 124378..124638 (261 bp)
Type: Antitoxin
Protein ID: WP_017061972.1
Location: 127722..128069 (348 bp)
Type: Others
Protein ID: WP_230682258.1
Location: 128069..128257 (189 bp)
Type: Others
Protein ID: WP_048659324.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OC193_RS24810119650..119772-123WP_259739813.1hypothetical protein-
OC193_RS24815121481..122506+1026WP_048660681.1hypothetical protein-
OC193_RS24820122503..123417+915WP_048660680.1AAA family ATPase-
OC193_RS24825123599..124072+474WP_230690977.1recombinase family protein-
OC193_RS24830124076..124378-303WP_017061973.1type II toxin-antitoxin system RelE/ParE family toxinToxin
OC193_RS24835124378..124638-261WP_017061972.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
OC193_RS24840124854..125411+558WP_048659321.1recombinase family protein-
OC193_RS24845125583..125903+321WP_080967496.1type II toxin-antitoxin system RelE/ParE family toxin-
OC193_RS24850125993..126292+300WP_048659322.1HigA family addiction module antitoxin-
OC193_RS24855126461..127147+687WP_048659323.1IS6 family transposase-
OC193_RS24860127722..128069-348WP_230682258.1hypothetical protein-
OC193_RS24865128069..128257-189WP_048659324.1hypothetical protein-
OC193_RS24870128374..128610+237WP_048659326.1hypothetical protein-
OC193_RS24875128621..128794+174WP_162200897.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..237546237546


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-57)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11782.63 Da        Isoelectric Point: 9.8778

>T40316 WP_017061973.1 NZ_AP025478:c124378-124076 [Vibrio crassostreae]
MMHYKLSSAAQSDLIEIRRYTLERWGQTQWTTYFSELKQSMELLANNQLLGIEVSELGKNYFRFPLKHHVIYYIQKQNHI
VIAAVLGKHMSPAKHFSQLS

Download         Length: 303 bp

>T40316 NZ_AP025478:c124378-124076 [Vibrio crassostreae]
ATGATGCACTACAAGCTTTCTTCTGCAGCGCAATCTGATCTCATTGAGATTCGTCGCTATACATTAGAGCGATGGGGGCA
AACACAATGGACGACTTACTTTTCAGAGCTCAAGCAATCAATGGAATTACTGGCGAACAACCAGCTGCTTGGCATAGAAG
TTTCTGAACTGGGAAAAAACTACTTCCGGTTTCCTTTAAAGCACCATGTGATTTATTACATCCAAAAGCAAAATCACATT
GTGATTGCAGCCGTTCTTGGTAAGCACATGTCACCTGCCAAGCACTTTTCACAACTCTCTTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9586.94 Da        Isoelectric Point: 4.3867

>AT40316 WP_017061972.1 NZ_AP025478:c124638-124378 [Vibrio crassostreae]
MQSLTANTAKTKFGDLLMKVQREPVQINKNGSPVAVMMSCEEYEQLEALKLMVVKSRFEQAEADALSDNLVDGNDFMNAL
NQGKFD

Download         Length: 261 bp

>AT40316 NZ_AP025478:c124638-124378 [Vibrio crassostreae]
ATGCAATCACTTACTGCTAATACAGCTAAAACCAAATTTGGTGACTTACTGATGAAGGTTCAACGTGAACCTGTACAAAT
TAATAAGAACGGTTCACCCGTTGCGGTGATGATGTCTTGTGAAGAATATGAACAACTTGAAGCACTCAAATTGATGGTGG
TGAAATCACGCTTCGAACAAGCAGAGGCCGATGCTCTATCAGATAACCTGGTCGACGGTAACGACTTCATGAACGCACTT
AACCAAGGTAAATTTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1B1C333

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1B1C393

References