Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 726597..728161 Replicon chromosome
Accession NZ_AP025476
Organism Vibrio crassostreae strain LMG 22240

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag OC193_RS03365 Protein ID WP_048658807.1
Coordinates 726597..727913 (-) Length 439 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag OC193_RS03370 Protein ID WP_017110259.1
Coordinates 727913..728161 (-) Length 83 a.a.

Genomic Context

OC193_RS03350OC193_RS03355OC193_RS03360OC193_RS03380OC193_RS03385OC193_RS03365OC193_RS03370OC193_RS03375
Location: 722667..723395 (729 bp)
Type: Others
Protein ID: WP_048663715.1
Location: 723477..724286 (810 bp)
Type: Others
Protein ID: WP_048663714.1
Location: 724592..726472 (1881 bp)
Type: Others
Protein ID: WP_048663713.1
Location: 729976..731544 (1569 bp)
Type: Others
Protein ID: WP_048666241.1
Location: 731741..732445 (705 bp)
Type: Others
Protein ID: WP_048666242.1
Location: 726597..727913 (1317 bp)
Type: Toxin
Protein ID: WP_048658807.1
Location: 727913..728161 (249 bp)
Type: Antitoxin
Protein ID: WP_017110259.1
Location: 728921..729769 (849 bp)
Type: Others
Protein ID: WP_048666240.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OC193_RS03350722667..723395+729WP_048663715.1DUF429 domain-containing protein-
OC193_RS03355723477..724286+810WP_048663714.1M15 family metallopeptidase-
OC193_RS03360724592..726472+1881WP_048663713.1RimK/LysX family protein-
OC193_RS03365726597..727913-1317WP_048658807.1type II toxin-antitoxin system HipA family toxinToxin
OC193_RS03370727913..728161-249WP_017110259.1type II toxin-antitoxin system antitoxin HipBAntitoxin
OC193_RS03375728921..729769-849WP_048666240.1hypothetical protein-
OC193_RS03380729976..731544+1569WP_048666241.1hypothetical protein-
OC193_RS03385731741..732445+705WP_048666242.1inovirus Gp2 family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-402)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-63)


Sequences

Toxin        


Download         Length: 439 a.a.        Molecular weight: 49398.65 Da        Isoelectric Point: 7.5312

>T40314 WP_048658807.1 NZ_AP025476:c727913-726597 [Vibrio crassostreae]
MQQLNAYMNGELVGTLTKQNNGSHEFKYNESWLSNDKSRPLSLSLKLQIPTITSDAVINYFDNLLPDNIAIRNRIVARYQ
TASNQPFDLLKEIGKDSVGAIALLPPSQPYIENKLSYELLDESRLEKILAAHHSNIPLGMIKEEDDFRISVAGAQEKTAL
LRLNGDWCLPKGNTPTSHIIKLPIGEIKQPTSILDLTESVENEFICIELARELGFDVPTVEIITTHNYKAIAVERFDRRW
IKDRTHLLRLPQEDICQAKGIPSSIKYESDGGPGIADIMKLLEGSSNALEDRYNFMKFQVFQWAIGAIDGHAKNYSIFIE
KQGSYRLTPFYDILSAYPITGKKGLNIRKLKLAMGLKASRGKKYQISKIYSRHFLDTAHSVGFNSDSMQSILDDMQTELP
KAIERLAARLPEGFPKHITEAIFDNSIAMLNKLNLSKN

Download         Length: 1317 bp

>T40314 NZ_AP025476:c727913-726597 [Vibrio crassostreae]
ATGCAACAACTTAATGCCTACATGAATGGTGAGTTGGTCGGTACTCTCACAAAGCAAAACAATGGCTCTCACGAATTTAA
ATATAATGAGTCTTGGCTCAGTAACGACAAATCTCGCCCATTATCTTTATCCCTTAAACTACAAATACCTACGATAACTT
CTGATGCCGTTATCAACTACTTTGACAACCTGCTACCAGACAATATTGCTATACGTAATAGGATTGTTGCACGCTATCAA
ACGGCTTCAAATCAACCTTTTGATCTTCTGAAAGAAATTGGCAAAGACAGCGTTGGTGCCATTGCTCTGCTCCCTCCAAG
TCAACCCTATATCGAGAACAAACTGTCATACGAACTTCTTGACGAATCTCGGCTTGAAAAAATCTTAGCAGCCCATCATT
CCAATATTCCATTAGGTATGATTAAGGAAGAAGATGATTTCCGAATATCGGTTGCTGGCGCTCAAGAAAAAACAGCATTG
CTAAGGTTGAACGGAGATTGGTGTTTGCCTAAAGGGAATACACCTACAAGCCATATCATTAAGCTACCTATTGGTGAGAT
TAAGCAGCCCACATCTATTCTAGATCTGACTGAAAGTGTCGAGAATGAGTTCATCTGTATTGAGTTAGCTAGAGAGTTGG
GGTTTGATGTTCCGACCGTCGAGATCATCACAACCCATAATTATAAAGCCATTGCTGTTGAGCGTTTTGATAGACGTTGG
ATTAAGGATCGTACACACCTACTGCGCCTTCCTCAGGAAGATATCTGTCAAGCCAAAGGAATCCCTTCATCGATAAAATA
CGAAAGTGATGGAGGCCCCGGAATCGCCGATATTATGAAGCTACTTGAAGGCTCATCCAATGCACTGGAAGACAGATATA
ACTTCATGAAGTTTCAAGTTTTCCAATGGGCTATAGGCGCTATTGATGGGCATGCAAAGAACTATTCAATATTTATTGAA
AAGCAAGGTAGTTATCGCTTAACACCATTTTATGACATTTTGTCTGCTTACCCTATCACGGGGAAAAAAGGACTAAACAT
AAGAAAATTAAAGTTAGCAATGGGATTAAAAGCAAGTCGTGGTAAGAAGTACCAAATAAGCAAGATCTACTCTCGCCACT
TTCTTGATACAGCCCATTCAGTTGGCTTTAATTCTGATAGCATGCAAAGCATATTGGATGACATGCAAACTGAATTACCC
AAAGCAATTGAGCGCCTCGCCGCACGCTTGCCTGAAGGTTTCCCAAAACACATAACCGAAGCTATCTTTGATAACTCTAT
TGCCATGCTTAACAAATTGAATTTGAGCAAGAACTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9416.80 Da        Isoelectric Point: 9.7278

>AT40314 WP_017110259.1 NZ_AP025476:c728161-727913 [Vibrio crassostreae]
VIYSPQQLANTLLLIRQKNRWTQSELAKKVGIKQATISNFENRPEKATISTMFKLIQALDLTLKIEPKDAKNSQSTVDEE
DW

Download         Length: 249 bp

>AT40314 NZ_AP025476:c728161-727913 [Vibrio crassostreae]
GTGATTTATAGCCCACAACAATTAGCCAATACTTTACTGCTAATACGCCAAAAGAATAGGTGGACTCAGTCTGAGCTGGC
AAAAAAAGTAGGGATAAAACAAGCAACCATTTCGAACTTTGAAAATAGACCAGAAAAGGCAACTATTTCAACAATGTTCA
AGCTTATCCAAGCATTAGATCTCACCCTTAAAATCGAACCCAAAGATGCAAAAAATAGTCAAAGCACTGTTGATGAGGAA
GATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References